Regenerative medicine options like stem cell treatments are growing in popularity both because of their potential effectiveness and because they can help you avoid invasive procedures like surgeries. Stem cell therapies focus on helping your body improve what it already does naturally — heal injuries.
Stem cells are the cells from which all differentiated cells form. They can come from your bone marrow or fat, with some people also turning to umbilical cord stem cells for treatment. But how do you know if you could benefit from stem cell therapy?
Those With Sports Injuries
If you play sports, you know that injuries can occur at any moment. You can twist your body in an unnatural way or suffer an impact that damages joints or ligaments. Minor injuries usually benefit from ice packs and rest, but healing can take time.
Healing is also a delicate process that can be disrupted. If that occurs, the injury might not heal completely and could lead to chronic issues that impact your mobility and even cause lasting pain.
When you turn to stem cell therapies, you can speed up the healing process. This type of regenerative medicine helps reduce inflammation, making it easier for nutrients and oxygen to get to the site of the injury.
Increased oxygen and nutrients are particularly important when dealing with ligaments and cartilage, which naturally don’t receive much blood flow.
Those With Arthritis
Arthritis is a debilitating condition in which your joints’ cartilage starts to deteriorate. The cartilage is what cushions your joints, preventing the bones from rubbing against one another. Once the cartilage breaks down, you can experience pain, stiffness, and mobility issues. In some cases, it can even cause joint deformity.
Stem cells, especially mesenchymal stem cells, release anti-inflammatory factors that help with pain and encourage your body to heal the damaged areas. Stem cells injected into the affected joint can reduce swelling, helping reduce pain and also restoring some mobility to stiff joints.
One of the best things about stem cell therapies for arthritis is that this kind of treatment is minimally invasive.
Those With Spinal Cord Injuries
Spinal cord injuries may severely impact your quality of life. You may struggle to perform everyday tasks and could face mobility issues that leave you dependent on others.
Spinal cord injuries are particularly difficult to treat because healing tends to plateau as a result of microenvironmental changes like inflammation, glial scar formation, and more. Stem cells can help because of their power to reduce inflammation, allowing the healing process to continue.
Ongoing treatment with stem cells could offer an improvement in mobility and a reduction in pain levels.
Those With Traumatic Injuries
After a major injury, like one that results from a car accident, healing can seem impossible. You may experience significant pain and could be dealing with mobility concerns that require physical therapy and even surgery.
Stem cell therapy works well in conjunction with physical therapy and other treatments because it utilizes cells from your body gathered in a minimally invasive way. You can continue other therapeutic programs while giving your body the chance to reduce inflammation so that blood can reach the injury site.
A better level of blood flow to the area not only brings nutrients and oxygen but also helps flush out toxins at the injury site that could make the symptoms worse.
Those Who’ve Gone Through Surgery
Going through surgery can put a lot of strain on your body. That is one of the reasons why the recovery process is often so long. If you’ve been through a surgical procedure, consider stem cell therapy.
Stem cell therapy can help reduce the recovery time so that you can start feeling more like yourself again. Inflammation is a huge concern. Think of the kinds of bruising you may have after a surgical procedure. Although stem cell therapy can’t prevent all inflammation and bruising, its use after surgery can reduce how much you experience.
If there’s less inflammation, the area can receive more nutrients and experience faster healing.
Those Who Need Joint Replacements
Replacing a joint is a surgical procedure that requires the implantation of an artificial joint and the removal of the damaged one. The recovery process for this type of procedure tends to be difficult, with many people experiencing mobility issues even as they heal because the artificial part hasn’t really integrated into the rest of the tissue.
If this type of surgery is something that you have to go through, adding stem cell therapy to the recovery process makes a difference. Stem cell therapies encourage the growth of new tissues around the artificial replacement that can make mobility easier and decrease pain, helping you get back to your life more rapidly.
Those With Degenerative Diseases
Degenerative diseases are chronic conditions that progressively get worse. They include diseases like:
For these conditions, a combination of treatments is usually most effective. They can include medications, physical therapy, and even surgery. By also turning to stem cell therapy, you have the chance to tackle the underlying cause of the problem so that you can get relief from symptoms.
Stem cell therapy for Parkinson’s disease, for example, focuses on helping restore the failing neurons that are in charge of producing dopamine. This could help with the management of dopamine levels and could even restore some function. In many instances, stem cell therapy for Parkinson’s can even slow down the disease.
Is Stem Cell Therapy Right for You?
Stem cell therapy might be able to offer the help you need with managing degenerative conditions, healing injuries, and providing pain relief that doesn’t rely on narcotics. You don’t have to worry about suffering allergic reactions or rejections because stem cell therapies usually rely on cells from your body.
If you’re considering stem cell treatments or want to know more about what the process involves and what you can expect, talk with a regenerative medicine specialist about the options available.
According to the World Health Organization, lower back pain affects 619 million people around the world. Lower back pain is an issue that people of all ages suffer from, and it can be debilitating. Many conditions, injuries, and damage can lead to this kind of back pain.
If you’re struggling, understanding the causes of the problem can help when deciding on the right treatment. Let’s take a closer look at the causes of lower back pain.
Muscle Strain or Sprain
Perhaps the most common reasons people experience lower back pain are muscle strains and sprains. These issues can occur gradually from overuse, or they can occur suddenly after an injury.
A low back strain occurs if you stretch the muscles that hold your spinal column in place. Tiny tears can form, leading to weaker muscles that have a harder time holding the bones of your spinal column correctly. That leads to the spine being less stable, which causes lower back pain.
A sprain occurs when the ligaments, which are the bands of tissue that hold bones together, tear away from their attachments. This, too, can happen from overuse or from an injury. The most common symptoms of muscle strains or sprains are muscle spasms, stiffness, and pain.
Degenerative Disc Disease
Degenerative disc disease is a condition in which the cushioning in your spine wears away. Your spinal discs are cushions between the bones (vertebrae) in your spinal column. They help you move and act as shock absorbers.
However, as you age, these discs begin to wear away, leading the bones to start rubbing together. Injuries and diseases can also wear away the discs.
Some of the symptoms of degenerative disc disease are:
Pain that worsens when bending, lifting, or sitting
Numbness and tingling in your legs or arms
Pain that radiates down to your lower back and buttocks
The symptoms can come and go, and they can last for weeks or months at a time. The pain can range from mild to severe.
Herniated Discs
Herniated discs are injuries to the spine. Between the vertebrae in your spine are cushions called discs. The discs function as buffers, letting you move around with ease. If one of these discs tears or leaks, you have a herniated disc.
It’s a condition that affects men more than women, and it’s more likely to occur in people who sit for long periods, lift heavy objects, perform repetitive twisting or bending motions, or smoke.
Discs have gel-like centers and a firm outer layer, which can crack over time. When the inner gel-like substance pushes through the crack, you have a herniated disc. That leaked material can press on spinal nerves.
Sciatica
Sciatica is nerve pain that occurs because of an injury or irritation to the sciatic nerve. You have two sciatic nerves, one on each side of the body, that run down your legs until they reach below your knee, where they then split into other nerves. Pain that occurs anywhere along that nerve is considered sciatica pain.
Herniated discs can cause sciatica as can arthritis, degenerative disc disease, and injuries. You are more at risk if you are obese, don’t have a strong core, or have a job that requires lots of lifting.
Osteoarthritis
This is the most common type of arthritis, and it occurs when the cartilage that covers your joints wears down over time, allowing your bones to rub together. Cartilage functions like a shock absorber as well as a lubricant, letting the bones that make up your joints move smoothly. With arthritis, this movement is more difficult and painful.
One of the most commonly affected areas is the lower back. Although it’s not entirely clear what causes osteoarthritis, scientists believe it occurs as a result of aging, health conditions that affect your joints, falls, and other accidents.
Spinal Stenosis
Spinal stenosis is a condition in which the space around your spinal cord becomes too narrow, leading to irritation of the cord or the nerves that branch off from it. You can think of your spinal canal as a tunnel that runs through each of the vertebrae that make up your spine. Your spinal cord is contained within this tunnel.
If the space narrows, your nerves can become compressed or pinched, causing back pain. Symptoms can depend on the type of spinal stenosis you have and can include:
Heavy feeling in your legs
Tingling or numbness in the foot, leg, or buttocks
Pain that gets worse when you stand or walk for a long time
Pain in your lower back
You can have acquired spinal stenosis, meaning it develops over time, or congenital spinal stenosis, which you have from birth. Herniated discs, osteoarthritis, spinal injuries, and many other conditions can cause it.
Spondylolisthesis
Spondylolisthesis is a condition that causes lower back pain, and it occurs when one of the bones in your spine slips out of place and onto the bone below it. This can put pressure on a nerve, resulting in back or leg pain.
Common symptoms of spondylolisthesis include:
Difficulty walking or standing for long periods
Back stiffness
Hamstring muscle spasms
Pain when bending
Foot tingling, weakness, or numbness
Young athletes, especially gymnasts and football players, are at risk. Some people are born with spondylolisthesis.
Fractures
If you have a fracture in a bone in the lower back, this can also cause lower back pain. Fractures can occur from traumatic injuries like falls or conditions like osteoporosis.
Regenerative Medicine for Lower Back Pain
No matter what is causing your lower back pain, you can get relief from symptoms. Most people turn to pain medications and anti-inflammatories to treat back pain, but all that those drugs do is hide the symptoms. They don’t get to the underlying cause of the problem. Regenerative medicine offers something different.
Regenerative medicine, also known as stem cell therapy, stimulates the natural healing process that you need to start feeling better. Turn to your healthcare provider to see if it’s the right choice for you.
Treatment of injuries and damage to organs and other tissues as a result of the aging process or conditions has often relied on managing symptoms. By offering painkillers and steroids, healthcare providers can keep you more comfortable, but they are not targeting the cause of the problem. This means you have to keep relying on medications. One option more people are exploring is regenerative medicine, also known as stem cell therapy. This type of regenerative medicine offers the chance to treat the underlying cause of the issue so that you can achieve lasting relief. In this article we will discuss how does stem cell therapy work?
What Is Stem Cell Therapy?
Stem cell therapy utilizes stem cells, which are those that create specialized cells. They can regenerate damaged or dying cells. Although you retain stem cells throughout your life, the aging process can make them less effective. This aging can lead to injuries that don’t heal completely, causing chronic pain and many other problems.
The goal of stem cell therapy is to amplify your body’s natural healing processes. To do this, it relies on stem cells.
In stem cell therapy, these cells are often harvested from the patient’s own body or from donors, and then administered to the affected area or systemically. The goal is to encourage tissue regeneration, repair damaged cells, and promote healing. Stem cells can differentiate into the specific cell types needed to replace or repair damaged tissues, making them a promising treatment for a wide range of conditions.
Stem cell therapy is a less invasive option than many other therapies. It requires the removal of stem cells from fat or bone marrow and then the injection of the prepared stem cells at the site of the damage. This not only makes it a viable option for those who can’t undergo surgery, but it also means the recovery process is shorter.
Another benefit of stem cell therapy is that it helps reduce inflammation. When you get injured, your body responds by causing inflammation to prevent the spread of damaging agents while also helping remove pathogens and cell debris. Inflammation also helps prepare the area for the repair process.
In some instances, however, inflammation doesn’t go away, leading to chronic pain. Inflammation also makes it more difficult for the wound to heal because the area is not receiving enough blood.
Stem cell therapy helps reduce this inflammation, allowing oxygen and nutrients to make their way to the damaged area. Less inflammation results in less pain.
Stem cell therapy is also a quick procedure. It can be done as an outpatient option, and it doesn’t require general anesthesia. Because most people benefit from adult stem cells, the procedure also avoids the need to worry about rejections or allergic reactions.
What to Expect from the Stem Cell Therapy Procedure
The first thing you will need to do is reach out to your healthcare provider to see if you are a good candidate for stem cell therapy. Your provider will go through your medical history to see which types of stem cells you can benefit the most from. The kind of condition or injury you have will impact this choice.
If you’re using your own stem cells, your healthcare provider will collect a sample from your bone marrow or fat. They then process them in a laboratory to isolate and concentrate them. In some cases, the process can involve centrifugation, filtering, and other options to help collect the highest number of stem cells.
The next step is receiving the stem cells, which can take place intravenously, with an injection, as well as other administration techniques.
After you receive the stem cells, your healthcare provider will monitor you to ensure there are no complications. They will also schedule follow-up phone calls to monitor how you are doing post-treatment.
Most people can get right back to their daily activities with some minimal post-treatment guidelines without having to worry about long recovery times.
Available Stem Cell Treatments
How does stem cell therapy work & what are the available treatments? Stem cells can help treat a variety of conditions. It’s helpful in treating cartilage regeneration and osteoarthritis because the stem cells can differentiate into chondrocytes, which are cells that maintain cartilage.
It’s also an option that can help with scar reduction and wound healing. For this procedure, stem cells derived from fat cells are a good option. They can help with tissue regeneration, potentially leading to healing chronic wounds and even the prevention of scarring.
Stem cell therapy is also a good choice for neurodegenerative issues. It can help replace neurons and provide neuroprotective benefits, potentially leading to slowing down the disease’s progression.
Stem cell therapy may also target ligament and tendon injuries, which are common in people who are very active. This type of therapy can help speed up the recovery process and might even be able to prevent the development of chronic pain issues that can affect mobility.
Another way stem cell therapy is able to help is by treating autoimmune diseases. Most autoimmune diseases are impacted by inflammation, so an option like stem cell therapy, which helps reduce swelling, can be helpful.
Choosing Stem Cell Therapy for Lasting Results
Stem cell therapy offers hope for the treatment of many types of conditions. By targeting the cause of pain and chronic injuries, like inflammation, you can avoid relying solely on pain medications, which only mask symptoms. Stem cell therapy makes it possible to have available options to help manage orthopedic injuries, neurodegenerative conditions, and much more.
If you want to learn more about how does stem cell therapy work and not sure whether stem cell therapy is a good option for your needs, speak with a regenerative medicine specialist. They can let you know if you are a good candidate.
After suffering an injury or experiencing any kind of damage to your body, it’s common to worry about how long the recovery process will take and wonder how soon you’ll be back to your normal self. The answer greatly depends on your physical health, the type of injury you face, and the treatments you’re receiving.
By understanding the drawbacks some traditional treatment options offer, especially when speaking about orthopedic injuries, and knowing more about options like stem cell therapy, you’ll be better able to make informed decisions about your treatment. Learn more about how regenerative medicine options, such as stem cell therapy, can impact the recovery process.
Why Traditional Treatments Aren’t Always Right
In orthopedics, healing takes significant time. It’s important to note, however, that one of the most common treatment options — surgery — only extends the time necessary to fully heal.
The typical healing period for someone who has undergone orthopedic surgery, even minimally invasive options, is several weeks. And that time refers only to the healing needed so that you can be up and walking around again — it does not mean being back to your full strength or regaining your flexibility.
This is why it’s common to see professional athletes take several months to recover after an injury that required surgery. As you recover, you also have to take pain medications and other drugs.
If you don’t choose the surgery route, another traditional option is steroids. These relieve pain and reduce inflammation, but they cause more damage to the injured area. They can cause a decrease in blood supply to the bones in the joints, leading to them weakening. Also, they can potentially accelerate cartilage damage.
Turning to pain medications alone does help reduce pain, but because they don’t do anything to fix the problem causing the pain in the first place, all painkillers do is prolong the issue. Long-term use of pain medications has its own health risks, which you will want to weigh against the benefits the medications provide.
Taking steroids and turning to painkillers will generally only delay the need for surgery. They don’t stop the progression of the problem that causes pain, allowing it to worsen while masking the symptoms. And while surgery is often successful at treating the injury, its cost and invasiveness mean it is not a viable option for everyone.
Understanding Stem Cell Therapy
Stem cells are your body’s building blocks. They are the cells that divide to form daughter cells that become other stem or specialized cells.
Stem cells can generate healthy cells to replace those damaged or affected by disease. They can be guided to become specialized cells, helping repair and regenerate tissues throughout the body.
There are three types of stem cells — embryonic, perinatal, or adult stem cells. Embryonic stem cells come from donated embryos that are three to five days old and contain an inner cell mass. These are pluripotent cells, meaning they can become any type of cell in the body or more stem cells. Due to the controversy of using these stem cells, they are primarily used in research only.
Perinatal stem cells come from amniotic fluid or umbilical cord blood. These stem cells can transform into specialized cells.
Adult stem cells are present in most tissues in the adult body, including fat tissues, bone marrow, or umbilical cord tissue. Although their abilities are slightly more limited than those found in embryonic stem cells, they are still potent and can create all kinds of human cells. Adult stem cells break down into many different types, including:
Mesenchymal stem cells
Hematopoietic stem cells
Skin stem cells
Neural stem cells
Epithelial stem cells
Stem cell therapy refers to the use of stem cells to promote the repair response of injured, diseased, or dysfunctional tissues. Stem cell therapy requires the preparation of the cells, which are usually obtained from your body and then injected into the treatment area.
How Stem Cell Therapy Helps
Stem cell therapy stimulates your body’s natural healing response. When a part of your body has inflammation, which is a natural response to an injury, it receives less blood.
The stem cell therapy reduces inflammation, which helps decrease pain while also improving blood circulation. More blood means the injured area receives the nutrients and oxygen it needs to heal itself.
Stem cell therapy allows for the management and healing of the problem. It doesn’t just mask the symptoms or delay the need for surgery; instead, it helps the formation of healthier tissues in the areas where they are needed.
Another benefit of stem cell therapy is that it doesn’t require any invasive procedures. All that is necessary is to extract stem cells from your body and enhance them before injecting them at the treatment site.
Unlike surgery, you don’t have to worry about a long recovery time or having to rely on help from others to manage everyday life as you heal. If you are someone who can’t go under general anesthesia, this is an option to consider. It is an outpatient procedure, allowing you to go home right after.
With stem cell therapy, you also don’t have to stress about participating in physical therapy for months, as you would have to do after surgery. It is an option that allows you to get back to your life as quickly as possible.
Relying on Regenerative Medicine
As one of the branches of medicine that holds promising potential, people are exploring regenerative medicine options like stem cell therapy. From autoimmune diseases to sports injuries and more, stem cell therapy, platelet-rich plasma, and other regenerative medicine options can help.
Not everyone can have surgery, and not everyone wants to depend on steroids and pain medications to feel relief.
By turning to an option that focuses on getting to the underlying problem causing the pain, you have an opportunity to see faster results without worrying about a long recovery process or dealing with general anesthesia. Give your body the chance to heal itself by considering stem cell therapy.
Currently, 1 in every 4 adults suffer from chronic knee pain; this represents a 65% increase over the last 20 years. While knee pain can be caused by several causes, including meniscus tears, tendinosis, sprains, rheumatoid arthritis, and lupus, osteoarthritis (OA) remains the most common contributor to this condition.
In this study, Lee and Padgett evaluate the use of the peptides BPC157 and thymosin-beta-4 (TB4) for the treatment of knee pain. Specifically, as part of this study, 17 patients received peptide therapy consisting of BPC157 or a combination of BPC157 and TB4 injections for their knee pain.
It is estimated that the human body has nearly 300,000 peptides. These peptides consist of chains of amino acids that range from 2 to 100 amino acids in length. One specific peptide, BPC157, when isolated, has demonstrated restorative properties that have helped in the repair of tendons, ligaments, muscles, nerves, and bone fractures. BPC157 has also been found to promote recovery from traumatic brain injury (TBI), reduce blood clots, and protect the liver.
Because of its reported acceleration of recovery from ruptured tendons, BPC157 has also become a favored therapeutic option by athletes looking to speed up the healing of their injuries. Prior to this study, no study using BPC157 in humans has been published, nor has this peptide received US Food and Drug Administration (FDA) approval in the United States.
TB4 is FDA-approved and a naturally occurring peptide that originates in the thymus gland. TB4 possesses a range of healing and regenerative properties, including accelerating recovery from skin wounds, TBI, stroke, and multiple sclerosis. TB4 has also been shown to reduce inflammatory markers and pain.
The patients involved in this study either received only an intra-articular injection of BPC157 or a combination of both BPC157 and TB4 injections.
As a follow-up, and as part of this retrospective study, the author followed up with patients between 6 months and 1 year after receiving peptide injections in their knee. Of those receiving only the intra-articular injection of BPC157, 91.6% reported significant improvements in knee pain while 75% of patients who received both peptides showed significant improvement.
While treating knee pain with BPC157 and TB4 has demonstrated potential for future therapeutic options, the author calls for additional larger studies to better understand improvements in structural changes and increased collagen production in patients with OA-induced knee pain.
Lee concludes that this retrospective study demonstrates that BPC157 has been shown to help reduce knee pain and have prolonged effects lasting over six months, a significant benefit when compared to the documented short-lived results of steroid treatment. Source: “Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.” https://pubmed.ncbi.nlm.nih.gov/34324435/.
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