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Stem Cell Research

Rheumatologist discussing lupus research with an adult patient

Mesenchymal Stem Cells for Lupus: Understanding Their Potential and Limitations

A peer-reviewed review of research on mesenchymal stem cells in systemic lupus erythematosus, including potential uses, evidence, and limitations.

Expanded Umbilical Cord Blood Stem Cells: Helping Patients Recover Faster After Transplant

Expanded Umbilical Cord Blood Stem Cells: Helping Patients Recover Faster After Transplant

Making More From Umbilical Cord Blood Umbilical cord blood has been used as a source of blood-forming stem cells for decades. These cells can rebuild the blood and immune system after intensive treatment, making cord blood an important transplant option for people with serious blood disorders and cancers. One challenge, however, is that a single…

Umbilical Cord-Derived MSCs for Knee Osteoarthritis: A Closer Look at Pain and Joint Inflammation

Umbilical Cord-Derived MSCs for Knee Osteoarthritis: A Closer Look at Pain and Joint Inflammation

Looking Beyond Everyday Knee Pain Knee osteoarthritis can turn simple activities like walking, climbing stairs, or getting out of a chair into uncomfortable tasks. While cartilage changes are part of the condition, inflammation inside the joint can also play an important role in pain and stiffness. A recent randomized clinical trial explored whether umbilical cord-derived…

Physician discussing lung and immune-system research with an adult patient

Literature Review: Do Mesenchymal Stem Cells Suppress Systemic Cytokines in Lupus and COPD?

A peer-reviewed review of studies examining mesenchymal stem cells, systemic cytokines, lupus, and COPD.

Stem Cell-Derived Islets and Type 1 Diabetes: Restoring the Body’s Ability to Make Insulin

Stem Cell-Derived Islets and Type 1 Diabetes: Restoring the Body’s Ability to Make Insulin

Can the Body Make Insulin Again? For people with type 1 diabetes, daily insulin is essential because the immune system damages the pancreatic cells responsible for producing it. Researchers have been exploring whether regenerative medicine could someday replace some of those lost insulin-producing cells. A first-in-human Phase I study published in Cell took an exciting…

Umbilical Cord-Derived MSCs and Knee Osteoarthritis: A Closer Look at the Research

Umbilical Cord-Derived MSCs and Knee Osteoarthritis: A Closer Look at the Research

When Knee Pain Starts Getting in the Way Knee osteoarthritis can make simple things feel a lot harder than they should. Walking upstairs, exercising, standing for long periods, or even getting up from a chair can become uncomfortable as the joint gets stiffer and more painful over time. That’s why researchers continue to look for…

Neurologist discussing brain health research with an adult patient

Mesenchymal Stem Cells and Neuroinflammation: Understanding the Role of the Secretome

A peer-reviewed review of research on mesenchymal stem cells, their secretome, and neuroinflammation in neurological disorders.

Illustration of mesenchymal stromal cell signaling around neural connections

Can Regenerative Medicine Actually Repair Damaged Nerves?

Research suggests stem cell therapy may support nerve repair by calming inflammation, releasing growth factors, and encouraging Schwann cells to rebuild the protective myelin coating around damaged nerve fibers. Most of this evidence comes from lab and animal studies, with human research still developing. At Stemedix, we view stem cell treatment as one part of…

Umbilical Cord-Derived MSCs and Multiple Sclerosis: Exploring the Impact of Treatment Dose

Umbilical Cord-Derived MSCs and Multiple Sclerosis: Exploring the Impact of Treatment Dose

Exploring a Different Approach to Multiple Sclerosis Multiple sclerosis, or MS, is a condition in which inflammation and abnormal immune activity damage the brain, spinal cord, and nerves over time. Current treatments can help control relapses and slow progression, but researchers continue to explore new approaches that may also support the body's natural repair processes.…

Doctor discussing a brain scan with an adult patient

Literature Review: Mesenchymal Stem Cell Paracrine Signaling in Neuroinflammation

A peer-reviewed review of research on mesenchymal stem cell paracrine signaling, exosomes, and neuroinflammation.

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