Stem Cell Research

Neurologist discussing brain health research with an adult patient

Mesenchymal Stem Cells and Neuroinflammation: Understanding the Role of the Secretome

SCIENTIFIC STUDY REVIEW Featured Article: Mesenchymal stem cells and secretome as modulators of neuroinflammation in neurological disorders Original article: https://link.springer.com/article/10.1186/s12967-026-08052-x Neuroinflammation is the immune response that occurs within the brain and nervous system. In the short term, inflammation can help protect injured tissue and support repair. When it becomes prolonged or poorly regulated, however, it…

Doctor discussing a brain scan with an adult patient

Literature Review: Mesenchymal Stem Cell Paracrine Signaling in Neuroinflammation

Reviewed Evidence Reviewed Study 1: Exosomes Derived From Bone Marrow Mesenchymal Stromal Cells Promote Remyelination and Reduce Neuroinflammation in the Demyelinating Central Nervous System Authors: Zhang J, Buller BA, Zhang ZG, et al. Publication & Date: Experimental Neurology. 2022;347:113895. DOI / Link: https://doi.org/10.1016/j.expneurol.2021.113895 | PubMed Reviewed Study 2: Intranasal Delivery of Mesenchymal Stem Cell-Derived Exosomes…

Mature woman sitting on a living room sofa holding her painful foot in discomfort, accompanied by a circular anatomical inset showing inflamed nerve pathways in a foot.

What Types of Neuropathic Pain Can Regenerative Medicine Address?

Stem cell therapy is being explored for several types of neuropathic pain, including diabetic peripheral neuropathy, chemotherapy-induced nerve damage, sciatica from nerve compression, and post-surgical nerve injury. Diabetic peripheral neuropathy alone affects nearly half of people with diabetes, making it one of the most common nerve pain conditions we see. At Stemedix, we build personalized…

Umbilical Cord-Derived MSCs and Immune Thrombocytopenia: Exploring a New Approach to Immune Balance

Umbilical Cord-Derived MSCs and Immune Thrombocytopenia: Exploring a New Approach to Immune Balance

When the Immune System Targets Platelets Platelets may be tiny, but they play an essential role in helping the blood clot and preventing excessive bleeding. In people with immune thrombocytopenia, or ITP, the immune system mistakenly attacks and destroys platelets faster than the body can replace them. When platelet levels become very low, patients may…

Can Combining Umbilical Cord MSCs Make Regenerative Therapies More Consistent?

Can Combining Umbilical Cord MSCs Make Regenerative Therapies More Consistent?

Not All Stem Cells Behave Exactly the Same When we talk about umbilical cord-derived mesenchymal stromal cells, or UC-MSCs, it can be easy to think of them as one uniform type of cell. In reality, cells collected from different umbilical cords can behave differently in the laboratory. Some may grow faster, while others may be…

iPSC-Derived Corneal Cells: A New Way to Help Restore the Eye’s Surface

iPSC-Derived Corneal Cells: A New Way to Help Restore the Eye’s Surface

When the Eye Loses Its Ability to Repair Itself The cornea is the clear outer surface at the front of the eye, and it plays a major role in vision. To stay healthy, it relies on a steady supply of cells that help repair and renew its surface. When those regenerative cells are badly damaged,…

Biomedical illustration of neurological research involving mesenchymal stem cells

Mesenchymal Stem Cells and Neurological Disorders: Understanding Their Potential for Brain and Nerve Repair

Scientific Study Review Featured Article: Mesenchymal Stem Cells for Neurological Disorders Original article: Read the original study review on PubMed Central Neurological disorders such as stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's disease, and spinal cord injury can damage cells and connections within the brain and spinal cord. Because the central nervous system…

Umbilical Cord MSC Extracellular Vesicles: Exploring New Possibilities for Skin Regeneration

Umbilical Cord MSC Extracellular Vesicles: Exploring New Possibilities for Skin Regeneration

Tiny Messengers With Big Potential Healthy skin is constantly repairing, renewing, and adapting. Behind the scenes, skin cells communicate through biological signals that help coordinate many of these processes. One area gaining attention in regenerative medicine involves small extracellular vesicles, or sEVs. These tiny particles are released by cells and carry proteins and other biological…

Stem Cell Treatment Helps Patients with Difficult-to-Treat Autoimmune Diseases

Humans cannot practically live without an immune system. The immune system helps us prevent and fight off infections and detect and destroy cancer cells. For some, however, experience conditions that affect the immune system. Autoimmune diseases such as multiple sclerosis, polymyositis, atopic dermatitis, and rheumatoid arthritis can make day to day activities challenging. Patients who…

IV Therapy St Petersburg FL

Regenerative Medicine in St Petersburg Florida Welcome to St. Petersburg, the home to Stemedix headquarters and main campus facility in the Bayfront Medical Plaza. The facility’s location is within the Bayfront Hospital District which includes John Hopkins All Children Hospital and Bayfront Health St. Petersburg Hospital, a level II trauma, and tertiary care center. Stemedix…

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