Pain Management for Cervical Degenerative Disc Disease

Pain Management for Cervical Degenerative Disc Disease

If you suffer from neck pain or pain that radiates down the arm, you may have cervical degenerative disc disease (CDDD). CDDD develops with the cushioning in the discs of the cervical spine (the neck) begin to break down. This breakdown can happen due to injury, genetics, or normal wear and tear. Without the natural cushioning for protection, discs may become herniated, or the patient may develop spinal stenosis or osteoarthritis. Here we will talk about Pain Management for Cervical Degenerative Disc Disease.

Can I Avoid Cervical Degenerative Disc Disease?

Nearly everyone develops CDDD as they age. However, there are lifestyle changes you can make to help improve the health of your spine and cervical discs. In addition to protecting spine health, the following tips may help decrease pain for those who are already experiencing the degenerative process:

Eat a Healthy Diet

Moderating your intake of salt, alcohol, and caffeine may help keep your spine healthy, as can eating a balanced diet full of fresh food and lean protein.

Stay Hydrated

Discs lose water as they age, so proper hydration plays an important role in maintaining disc health. Water also helps to deliver nutrients to the spine and carry away wastes.

Exercise

Daily walking, light stretching, strength training, and other low-impact exercise helps maintain flexibility in the cervical joints and reduce pain associated with cervical degenerative disease.

Quit Smoking

Nicotine inhibits bone growth and decreases the amount of oxygen that gets delivered to the discs as well as the rest of the body’s systems.

Practice Good Posture

Proper alignment when you walk and sit helps to reduce pressure on the spine. This practice not only decreases the amount of wear on spinal joints but also decreases pain. This is great for pain management for cervical degenerative disc disease.

Treatments for Cervical Degenerative Disc Disease

Surgical treatments can often be avoided if non-invasive treatments are applied. Traditional pain management techniques include:

  • Prescription or OTC pain medications
  • Hot/cold therapy
  • Rest
  • Physical therapy
  • Massage, acupuncture, acupressure

Regenerative Medicine, also known as stem cell therapy, is a cutting-edge treatment offering potential to relieve pain from cervical degenerative disc disease.  

Patients who have recently developed CDDD symptoms, as well as those who’ve been living with the painful condition for many years, may benefit from safe, non-invasive stem cell treatment. Studies have shown that patients receiving stem cell therapy reported:

  • Fewer muscle spasms
  • Improved strength and mobility
  • A decrease in chronic pain levels
  • Less tingling, weakness, and numbness in extremities

Regenerative medicine may also help improve other orthopedic conditions such as sport’s injuries, osteoarthritis, and musculoskeletal injuries

Stem cell therapy is still considered experimental, and results are not guaranteed. However, it is a safe and minimally invasive treatment that could help CDDD patients manage their symptoms to help live a fuller, more active life free from chronic pain. If you are interested in learning more, contact us today and speak with a care coordinator.

Results for Stem Cell Treatment of Degenerative Disc Disease

Results for Stem Cell Treatment of Degenerative Disc Disease

Degenerative disc disease is one of the leading causes of neck and low back pain in adults. This medical condition results in many symptoms. It is caused by wear and tear on the spinal discs. In this article, we are going to talk about Stem Cell treatment of Degenerative Disc Disease.

Aside from back and neck aches, degenerative disc disease can result in: 

  • Numbness
  • Hot or shooting pains
  • Weakness 
  • A “giving out” sensation
  • Muscle spasms and tension
  • And more

The most common symptom of this condition is constant and low-level pain. Chronic pain can make it difficult to live a normal life. Because of the discomfort that comes from degenerative disc disease, researchers are looking for innovative treatments to help patients live more comfortably.  

Recent Phase III Trial Results for Stem Cell Therapies 

A recent randomized Phase III trial has shown that stem cell injections can help patients with degenerative disc disease. According to the study, a single injection provided long-term relief of back pain. The study was conducted using stem cell products from Mesoblast Limited, an Australian regenerative medicine provider.

Representatives from the company hope to meet with the Food and Drug Administration (FDA) to speed up the approval of their product. The product in question is known as “remestemcel-L.” The company has been developing this stem cell product for several years.

Like many stem cell treatments, the product is made using bone marrow to harvest mesenchymal stem cells. Those cells are then injected into patients’ bodies to reduce inflammation. The product inhibits the development of certain inflammatory substances. Decreased inflammation reduces the patient’s pain.

According to the trial report, sixty percent of the injected patients reported little to no pain after a year. After two years, 54% reported minimal or no discomfort. The injections provided the most pain relief for patients who were in the early stages of the disease.  

Reduced Use of Opioids  

Studies like the one discussed above have given many patients and medical professionals confidence in the potential of stem cells. In the study by Mesoblast Limited, more than 400 volunteers participated. Many of the patients who experienced pain relief decreased their use of opioids. Across the study group, opioid use declined by 40%.

Patients in the control group who received a saline injection actually increased their use of opioids. Because of this, the company hopes that the FDA will fast-track the approval of remestemcel-L as a standard treatment for degenerative disc disease.

Future studies will be necessary to determine the full potential of stem cell therapies. Still, many patients have experienced significant improvements in their health and wellbeing by using stem cell therapies. If you are interested in using stem cell treatment for Degenerative Disc Disease contact a care coordinator today to learn more!

Can You Live a Normal Life with Degenerative Disc Disease?

Can You Live a Normal Life with Degenerative Disc Disease?

Degenerative disc disease is an age-related condition that occurs when the discs of the vertebrae, located in the spine, deteriorate. Symptoms may include weakness, numbness, and radiating pain. The discs are responsible for absorbing shock, allowing the back to move freely. As they wear out, their ability to protect the vertebrae becomes limited. 

For people with the condition, symptoms like nerve and muscle pain, spinal instability, tingling and weakness in the muscles, and neurological symptoms may make it challenging to perform tasks. If your symptoms prevent you from being able to perform your work, having degenerative disc disease could qualify you for unemployment benefits. This is usually decided based on the degree of degeneration experienced.

While degenerative disc disease could require some modifications to your normal routine, however, it is possible to live a normal life with the condition. 

Ways to Lead a Normal Life with Degenerative Disc Disease

Finding a supportive team of healthcare professionals is one important pillar of maintaining your quality of life with degenerative disc disease. These experts may recommend the following tactics for controlling symptoms, or a combination thereof:

  • Optimizing your posture through physical therapy and ergonomic furniture to reduce pain
  • Using heat and cold therapies to control pain levels as needed
  • Seeking alternative treatments, such as regenerative medicine.
  • Taking over-the-counter pain relievers, such as ibuprofen or acetaminophen 
  • Staying physically active with low-impact exercise to maintain strength, stamina, and flexibility
  • Using physical therapy to maintain strength and range of motion in the back and neck

Thus, even if you have to be out of work for some time or indefinitely, there are many lifestyle tactics and therapies you can explore to feel your best while living with this disease. If you would like to learn more then contact us today and one of our care coordinators will be happy to help!

What’s the Best Treatment for Degenerative Disc Disease?

What’s the Best Treatment for Degenerative Disc Disease?

One of the most common causes of lower back pain, degenerative disc disease is an umbrella term for the symptoms that result from general wear and tear on a spinal disc. In addition to back pain, it can also cause shooting pains in the extremities, weakness, and numbness. In this article, we will talk about the best treatment for Degenerative Disc Disease.

While the condition can be frustrating, there are many ways to manage its symptoms. In fact, most cases involve periodic flare-ups, but the pain typically doesn’t intensify over time. For this reason, many people can avoid surgery for degenerative disc disease. 

Instead of going directly to surgical interventions, the goals of treating the condition usually entail:

  • Relieving pain to the point that patients can participate in rehabilitation programs or perform exercises at home without discomfort.
  • Preventing added stress to the back using ergonomics and improved posture.
  • Managing discomfort so individuals can go about their normal routine uninterrupted.

There are many lifestyle modifications, self-care options, and clinical therapies that can be tried before resorting to more invasive procedures. Here are a few common approaches:

  • Pain relievers: Over-the-counter pain medications such as NSAIDs and acetaminophen may help control pain levels during particularly intense flare-ups.
  • Chiropractic care: Some individuals find that manual manipulation performed by a chiropractor can reduce the pressure on sensitive areas of the back. 
  • Epidural injections: Spinal injections deliver steroids directly to the compromised area of the back to reduce inflammation and thus relieve pain.
  • Ultrasound: Ultrasound technology brings warmth to affected areas through sound waves, increases blood flow, and could potentially stimulate healing in some back injuries.
  • Massage therapy: Massage increases blood flow, alleviates tension in the muscles, and triggers the release of endorphins, all of which can help reduce pain levels.
  • TENS units: Using electrical stimulation, these units override pain signals in affected areas.

Some patients also use acupuncture and home therapies such as cool or warm compresses to reduce back pain caused by degenerative disc disease. Beyond these treatments, here are a few lifestyle modifications that may also help:

  • Smoking cessation: Smoking depletes oxygen, which your body needs to perform its best. Tobacco use and chronic pain often go hand-in-hand, so quitting could help you find relief.
  • Exercise: Working out may seem counterintuitive when you’re in pain, but many patients can achieve long-term healing through exercise. Aim for a combination of strengthening, stretching, and low-impact cardio moves.
  • Weight loss: Added weight puts stress on your spine, potentially intensifying your degenerative disc disease. Weight loss could reduce the stress on vertebrae and discs, alleviating back pain. 
  • Ergonomics: Ergonomics is the application of physiological principles to products such as furniture and footwear to help support healthy posture and minimize back pain. If you suspect your work environment could be contributing to your back soreness, it’s worth looking into supportive shoes, ergonomic furniture, and modifications to your posture. 

In addition to these treatments and lifestyle changes, patients seeking a nonsurgical treatment for degenerative disc disease may consider stem cell therapy. This form of regenerative medicine works at the site of injury and uses the body’s natural healing properties delivered through stem cells to repair and regenerate tissue. This treatment has been well-tolerated in studies and presents minimal risk and downtime, offering a convenient alternative to invasive procedures. If you want to learn more then contact a care coordinator today!

Exosomes Help Regenerate Intervertebral Disc Tissue: Implications For Degenerative Disc Disease

Exosomes Help Regenerate Intervertebral Disc Tissue: Implications For Degenerative Disc Disease

The spinal column is made up of more than a dozen vertebral bones stacked on top of each other. Since the spine is not a single bone, it is capable of pivoting and bending, which gives the torso a degree of flexibility. A key part of this structure relies on the substance between the vertebral bones called the intravertebral disc.

The intravertebral disc is made up of the annulus fibrosis (the tough outer ring) and the nucleus pulposus (the jelly-like inner core). Each intervertebral disc acts as a shock absorber between the vertebral bones. Over time and with age, however, the intervertebral disc tends to breakdown. This can cause called degenerative disc disease, which includes herniated discs (“slipped discs”), pinched nerves, neck and back pain, and nerve problems.  Obviously, finding ways to reverse or prevent intravertebral discs from breaking down is of great medical and scientific interest and for the countless patients with degenerative disc disease.

As with other groups interested in regenerative medicine, researchers have turned to stem cells in an effort to regenerate tissue within the intravertebral disc. One research group reported their recent success using bone marrow-derived mesenchymal stem cells. The scientists collected exosomes—very small packets filled with highly concentrated molecules such as proteins, microRNA, transcription factors and lipids—from these stem cells. In this study, researchers also collected exosomes from nucleus pulposus cells and tested the exosomes in various ways.

The researchers found that exosomes could send out signals to bone marrow mesenchymal cells and call them to the intervertebral disc. The exosomes also prompted the stem cells to become new nucleus pulposus-like cells. Conversely, exosomes from bone marrow mesenchymal cells caused nucleus pulposus cells to grow and multiply (i.e. proliferate). Finally, exosomes helped the tissue in degenerating vertebral discs to express the same genes as healthy discs.

While these results are complex, they suggest that exosomes from bone marrow mesenchymal cells and nucleus pulposus cells work together to recruit and make more healthy cells in degenerating vertebral discs. This could have profound implications for the millions of people with degenerative disc disease. If these results are confirmed in clinical trials, it would mean that exosomes could be used to prevent or reverse degenerative disc disease. We anxiously await further work in this exciting field.

Reference: Kang L. et al. (2017). Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells. Stem Cell Research Therapy. 2017; 8: 108.

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