Neurological disorders can affect the brain, spinal cord, and nerves, often leading to symptoms such as muscle weakness, pain, reduced mobility, memory changes, and loss of function. Conditions involving nerve injury or neurodegeneration are especially challenging because the nervous system has a limited ability to repair itself after damage. Because of this, researchers continue to…
Low back pain is a widespread issue that affects millions of people worldwide, significantly impacting their daily lives and placing a substantial financial strain on the healthcare system. Existing treatment options for low back pain often provide only temporary relief and come with various limitations. With the increasing interest in regenerative medicine, newer treatments like…
Respiratory diseases are a major global health concern, responsible for millions of deaths each year. Conditions like chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), pulmonary fibrosis, and pneumonia claim many lives annually, and despite advancements in medical research, there is still no cure for many of these diseases. Current treatments typically focus…
Osteoarthritis (OA) is the most common form of arthritis and is estimated to affect nearly 365 million people worldwide. Characterized as an inflammatory disease, OA slowly progresses over time and results in the gradual loss of the protective cartilage found on the ends of the bones. While the specific cause of OA has yet to…
According to the World Health Organization, at least 2.2 billion people worldwide have near or distant vision impairment. In at least 1 billion of these cases, vision impairment could have been prevented or has yet to be addressed. Glaucoma, corneal disease, and retinal disorders are among the leading contributors to these vision impairments. Since the…
Repairing the structure and functionality associated with subcutaneous cartilage defects continues to be a challenge in the fields of plastic and reconstructive surgery. While current methods, including autologous chondrocyte implantation and matrix-assisted chondrocyte implantation, have been successful in some regard, they continue to present a number of limitations, including donor limitation, donor morbidity, and degradation…
stem cell therapy for osteoarthritis (OA) is a chronic joint condition that causes pain and lack of mobility through the progressive degradation of joint cartilage. While there are several current pharmaceutical, physical therapy, and surgical treatments to address the symptoms of OA, researchers are interested in developing new therapeutic treatment approaches to address the relentless…
Systemic lupus erythematosus (SLE) is a common multisystemic stem cell therapy for autoimmune conditions that often results in multi-organ damage when left untreated. Currently affecting over 1.5 million Americans, the etiology and pathogenesis of SLE continue to remain unclear. At present, glucocorticoids and immunosuppressants are the most prescribed course of therapeutic treatment and mostly as…
Cardiovascular diseases continue to be the leading cause of death globally, accounting for nearly 18 million deaths each year with heart attack and stroke accounting for 80% of deaths. Recently, stem-cell-based therapy has demonstrated the potential to regenerate damaged myocardium and to treat a wide range of cardiovascular diseases (CVDs). Specifically, the ability of mesenchymal…
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