How Long Does Stem Cell Therapy Last for Hips?

How Long Does Stem Cell Therapy Last for Hips?

Hips are some of the strongest and largest joints in the body. They support the body’s weight and provide a wide range of motion. Despite their power, hips are susceptible to disease, trauma, and gradual degradation. Over time, hip joints can succumb to many different pathologies.  For example, osteoarthritis is one of the leading causes of pain in the hip. This can result from chronic overuse. Hip pain can result in many serious consequences. For instance, hip pain can limit a patient’s mobility and affect their ability to sleep. Pinched nerves, certain types of cancers, and infections can all lead to hip discomfort. Here we answer the question, How long does stem cell therapy last for hips?

Treatments for Hip Pain

There are many traditional medical treatments for hip joint discomfort. They include:

  • Pain medication
  • Rest
  • Arthroscopic surgeries
  • Physical Therapy
  • And more

In severe cases, hip replacement surgery may be necessary. Hip surgeries can be very difficult for patients. In many cases, they may result in significant pain and long recovery periods. Thankfully, there are options beyond traditional treatments for hip pain.  

Research over the past several decades has indicated that regenerative medicine, also known as stem cell therapy, may be useful for treating hip pain. 

Understanding Stem Cell Treatments

Stem cells are one type of simple cell that the human body produces. They can stimulate the growth of new tissue in many areas and systems in the body. Beyond that, stem cells encourage the body’s natural healing processes. These simple cells can be used to differentiate and potentially regenerate tissues.

In some cases, healing can be difficult when not enough stem cells are produced in a certain area. This sometimes contributes to hip pain and discomfort. The introduction of stem cells into a problem area can help motivate the growth and renewal of tissue in the hip joint. Stem cell therapies also have the potential to reduce painful inflammation in the hips and other joints.

Stem cell treatments are minimally invasive and have been shown to be safe. Some patients have used stem cell therapies to prevent the need for painful surgeries.

How Long Do Stem Cell Treatments Last?

sp, how long does Stem Cell Therapy last for hips? In most cases, patients treated with stem cell therapies can return to their normal activities within six weeks. 

The length of improvement in the patient’s hip pain may vary, depending on their condition. However, many patients have experienced years of hip pain relief from stem cell therapies.

Also, the minimally-invasive nature of stem cell therapies allows patients to receive further treatments, if necessary. This innovative approach to hip pain relief provides an exciting opportunity for patients everywhere. If you are interested in booking a consultation with a care coordinator contact us today!

Mesenchymal Stem Cells Injection Improves Hip Osteoarthritis

Mesenchymal Stem Cells Injection Improves Hip Osteoarthritis

Osteoarthritis of the hip is a painful condition that can interfere with leg movement and diminish the quality of life. In some, the symptoms are mild, but in others, osteoarthritis can be severe and can even lead to joint failure. Pain is often intermittent in early stages, but in later stages, the pain can be constant with periods of sharp, intense pain. The hip joint becomes stiff and unstable, making it difficult to move around and greatly increasing the risk of falls.

Unfortunately, there are few effective treatments for osteoarthritis of the hip. Management includes pain control with non-steroidal anti-inflammatory drugs and physical therapy. Steroid injections into the hip are not as effective as they are for knee osteoarthritis, so many doctors hesitate to perform them. Joint supplements such as glucosamine and chondroitin are unlikely to be very effective—clinical trials have not provided evidence that they actually work. The definitive treatment for hip osteoarthritis is hip replacement surgery, which is expensive and associated with a long period of recovery.

The main problem in osteoarthritis is that the joint breaks down over time from wear and tear (i.e. microtraumas). At the same time, the joint has a very limited capacity to heal itself. In other words, once the joint breaks down, it pretty much stays that way. Since life is a series of joint microtraumas, the hip gets progressively worse. Indeed, one in four people will have painful osteoarthritis of the hip by age 85, and hundreds of thousands will have it earlier in life.

Scientists have long wanted to find ways to help the body regenerate the joint substances, particularly joint cartilage. Unfortunately, the joint does not receive good blood supply and no known drug or supplement can actually rebuild joint cartilage. That is the main reason researchers are aggressively testing stem cells as a treatment for hip osteoarthritis.

Mesenchymal stem cells have the potential to become many different types of cells, including chondrocytes (cartilage cells). Mesenchymal stem cells sense the environment they are in and then become the cell consistent with that environment. So, the theory goes, injecting mesenchymal stem cells into the hip joint can prompt them to become hip joint cells (chondrocytes).

Researchers tested this hypothesis in a clinical study. They injected mesenchymal stem cells taken from fat tissue (i.e. adipose) and injected them into the hip joints of people with difficult-to-treat hip osteoarthritis. They compared the patients’ Harris Hip scores (HHS) before and 6 months after treatment. HHS is a reliable way to assess the severity of osteoarthritis symptoms. An HHS score of less than 70 is “poor” and a score of 80 to 90 is “good.” Before stem cell treatment, patients had an average HHS score of 67.2±3.4 and 84.6±6.3 afterward. Scores also improved in other tests including WOMAC and Visual Analogue Scale. In other words, mesenchymal stem cell treatment reduced pain and improved joint function in these patients compared to levels prior to treatment.

The authors of the clinical study state that “preliminary results are positive and promising.” Further research and studies will help to learn more about this regenerative medicine potential.

Reference: Dall’Oca, C. et al. (2019). Mesenchymal Stem Cells injection in hip osteoarthritis: preliminary results. ACTA Biomedica. 2019, 90(Suppl 1): 75-80.

Stem Cell Therapy for Newly Diagnosed Conditions

Stem Cell Therapy for Newly Diagnosed Conditions

Whether you’re suffering from a neurodegenerative condition like ALS or are recovering from a sports or athletic injury, regenerative medicine, also known as stem cell therapy, offers a host of potential benefits for treating your condition.  However, one of the most common questions we hear is when patients should seek to start stem cell therapy treatments. Of course, there’s no single, simple answer, since each patient’s case is unique. However, in general, results may be most optimal soon after newly diagnosed conditions. This does not mean results may not be beneficial if the condition or injury has been endured for a longer period. 

Is There a Time Consideration When to Have?

Stem cell treatments have a greater potential to help provide relief if the injury is relatively minor or if the condition is a newer diagnosis. For many conditions, that means seeking treatment early in the progression stage. If it is later, more subsequent therapies may be a potential need to help manage symptoms or the condition further.

Still, no matter how long you’ve been dealing with your condition, stem cells hold a potential alternative option to provide a management tool for some degree of improvement or stabilization. When it comes to stem cell therapy, it helps to think less in terms of shortening the problem and more in terms of how there is potential to help reduce the severity.

Treating Orthopedic Conditions

One of the most common reasons patients seek stem cell therapy is to help recover from a musculoskeletal injury. These injuries often cause pain in joints like the knee and the hip. By introducing stem cells into the affected area, it has the ability to stimulate regenerative and healing properties, which can help to lessen the severity of the injury.

When dealing with newly diagnosed conditions, it is important to allow time for the treatment to have its course of healing potential on the injury and body. It is important to also follow post-management care for the most optimal outcomes.

Considerations for Post-Treatment

Depending on your condition, you may need to avoid strenuous exercise or overuse of a joint or muscle for a period of time. However, many times you can simply return to everyday life, as long as you take care not to aggravate the area. 

It’s a good idea to block out a day for your treatment and plan for a short recovery period if an active lifestyle is a normal part of your day-to-day. You may experience some mild soreness, but in many cases, you will be able to resume your everyday life with careful healing instructions. If you would like to schedule a consultation contact a care coordinator today!

A Review of Mesenchymal Stem Cell Therapy in the Treatment of Osteoarthritis

A Review of Mesenchymal Stem Cell Therapy in the Treatment of Osteoarthritis

With nearly 30 million people in the US affected by osteoarthritis (OA), the condition continues to be among the leading causes of chronic pain and disability. Considering that advances in medical technology have increased overall life expectancy, the number of people living longer and dealing with the effects of OA is expected to increase for the foreseeable future.

Although modern medicine has improved the way most diseases and chronic conditions are diagnosed and treated, OA treatment has not benefited from these advances.  As a result, treatment and prevention of OA continue to focus primarily on controlling and minimizing symptoms associated with the condition, not treating or preventing the condition itself. Unfortunately, for many, when symptoms of OA progress to a point where the pain is no longer able to be managed, their options look to surgical replacement of the affected joint.

While there are many contributing factors related to the onset and progression of OA, including obesity, history of trauma, genetics, and heritable and acquired disorders, there also appears to be an association between the onset of OA and a depleted local population of mesenchymal stem cells (MSCs).

Considering the apparent relationship between OA and MSCs, Freitag et al. reviewed the reparative pathways, safety, and efficacy of MSC therapy in the treatment of osteoarthritis.

With their ease of harvest and ability to expand into chondrocytes, MSCs have continued to gain interest when exploring various stem cell therapies for the active management of pain and symptoms associated with OA.

Freitag et al. found that preclinical and clinical results of studies of cartilage repair techniques that utilize MSCs, including MSC scaffold transplantation techniques, MSC injectable techniques, MSC as a vehicle for platelet-rich plasma (PRP), and hyaluronic acid (HA) as an active carrier of MSCs, have all shown favorable results in supporting the benefits of MSC for the improvement of function and regeneration of new tissue in those afflicted with OA.

With over 400 active trials currently examining the efficacy of MSCs in the treatment of a variety of conditions, including OA, the safety of utilizing MSC therapy continues to draw interest from the medical community. 

Although some early studies appeared to raise the question of abnormal cell growth, and ultimately the safety, associated with MSC therapy, the authors’ systematic review of clinical trials found that, while caution needs to be undertaken when culturing MSCs, the evidence demonstrates MSCs are generally safe for therapeutic use for the treatment of OA.

Freitag et al. conclude that the rapid progression of OA and related conditions demonstrate the need for therapies that repair and prevent these diseases, not just manage pain and related symptoms. As such, the authors feel MSC therapy offers a safe and viable option for the eventual treatment and prevention of OA and calls for further randomized controlled trials to evaluate the most effective applications of MSCs for managing osteoarthritis.

Source:   (2016, May 26). Mesenchymal stem cell therapy in the treatment of osteoarthritis. Retrieved from https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-016-1085-9

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