by admin | Dec 14, 2023 | Parkinson's Disease, Mesenchymal Stem Cells, Regenerative Medicine, Stem Cell Research, Stem Cell Therapy
Parkinson’s disease (PD) is the second most predominant neurodegenerative disorder worldwide, affecting over 10 million people. Characterized by a slow and progressive loss of control of the neurological system as a result of dopamine depletion, symptoms of PD often include tremors, slowed movement, impaired posture and balance, and gradual loss of automatic movements.
While PD cannot be cured, current treatment is focused on alleviating symptoms and slowing the progression of the disease. Specifically, deep brain stimulation or therapies to increase DA levels by administering a DA precursor are the available therapy options for PD.
However, research has found that DA precursor therapy has little effect on the progression of PD and its efficacy decreases as the disease progresses.
Recent progress in the clinical understanding of regenerative medicine and its properties associated with stem cell therapy has provided the opportunity to evaluate new and potentially effective methods for treating a wide range of neurodegenerative illnesses, including PD. Specifically, mesenchymal stem cells (MSCs) have been found to be the most promising form of stem cell and have demonstrated the ability to differentiate into dopaminergic neurons and produce neurotrophic substances.
In this review, Heris et al. discuss the application of MSCs and MSC-derived exosomes in PD treatment.
Research has identified dysregulation of the autophagy system in the brains of PD patients, suggesting a potential role for autophagy in PD. In PD models, MSCs may activate autophagy signals and exhibit immunomodulatory effects that alleviate inflammation and improve tissue healing; this type of treatment had previously been used in treating various forms of neuroinflammatory and neurodegenerative illnesses.
The authors indicate that MSCs can be administered either systemically or locally. While systemic transplantation allows MSC-based treatment of pathologies affecting the entire body, local transplantation aims to alleviate symptoms associated with illnesses that originate from certain organs and is performed through intramuscular or direct tissue injection.
Research has also demonstrated that stem cell-derived dopaminergic transplants could be a suitable method for the long-term survival and function of transplants; in the case of MSC therapy, the average dose in animal models is usually 50 million cells for each kg of weight.
MSC-derived exosomes demonstrate therapeutic characteristics similar to their parents, have the ability to avoid whole-cell post-transplant adverse events, have a high safety profile, cannot turn into pre-malignant cells, and no cases of immune response and rejection have been reported.
While the use of MSCs in the treatment of PD continues to show potential, Heris et al. point out that many of the clinical trials have had few participants and can be costly. Considering these limiting factors, the results from these studies are not able to be generalized to everyday medical care without further clinical studies to address these concerns.
Source: “The potential use of mesenchymal stem cells and their exosomes in ….” 28 Jul. 2022, https://stemcellres.biomedcentral.com/articles/10.1186/s13287-022-03050-4.
by Stemedix | Dec 11, 2023 | Stem Cell Therapy, Alzheimer’s Disease, Autoimmune, Health Awareness, Osteoarthritis, Parkinson's Disease
Treatment of injuries and damage to organs and other tissues as a result of the aging process or conditions has often relied on managing symptoms. By offering painkillers and steroids, healthcare providers can keep you more comfortable, but they are not targeting the cause of the problem. This means you have to keep relying on medications. One option more people are exploring is regenerative medicine, also known as stem cell therapy. This type of regenerative medicine offers the chance to treat the underlying cause of the issue so that you can achieve lasting relief. In this article we will discuss how does stem cell therapy work?
What Is Stem Cell Therapy?
Stem cell therapy utilizes stem cells, which are those that create specialized cells. They can regenerate damaged or dying cells. Although you retain stem cells throughout your life, the aging process can make them less effective. This aging can lead to injuries that don’t heal completely, causing chronic pain and many other problems.
The goal of stem cell therapy is to amplify your body’s natural healing processes. To do this, it relies on stem cells.
In stem cell therapy, these cells are often harvested from the patient’s own body or from donors, and then administered to the affected area or systemically. The goal is to encourage tissue regeneration, repair damaged cells, and promote healing. Stem cells can differentiate into the specific cell types needed to replace or repair damaged tissues, making them a promising treatment for a wide range of conditions.
Stem cell therapy has shown potential in treating conditions such as heart disease, neurological disorders (e.g., Parkinson’s and Alzheimer’s disease), autoimmune conditions, and orthopedic injuries.
Benefits of Stem Cell Therapy
Stem cell therapy is a less invasive option than many other therapies. It requires the removal of stem cells from fat or bone marrow and then the injection of the prepared stem cells at the site of the damage. This not only makes it a viable option for those who can’t undergo surgery, but it also means the recovery process is shorter.
Another benefit of stem cell therapy is that it helps reduce inflammation. When you get injured, your body responds by causing inflammation to prevent the spread of damaging agents while also helping remove pathogens and cell debris. Inflammation also helps prepare the area for the repair process.
In some instances, however, inflammation doesn’t go away, leading to chronic pain. Inflammation also makes it more difficult for the wound to heal because the area is not receiving enough blood.
Stem cell therapy helps reduce this inflammation, allowing oxygen and nutrients to make their way to the damaged area. Less inflammation results in less pain.
Stem cell therapy is also a quick procedure. It can be done as an outpatient option, and it doesn’t require general anesthesia. Because most people benefit from adult stem cells, the procedure also avoids the need to worry about rejections or allergic reactions.
What to Expect from the Stem Cell Therapy Procedure
The first thing you will need to do is reach out to your healthcare provider to see if you are a good candidate for stem cell therapy. Your provider will go through your medical history to see which types of stem cells you can benefit the most from. The kind of condition or injury you have will impact this choice.
If you’re using your own stem cells, your healthcare provider will collect a sample from your bone marrow or fat. They then process them in a laboratory to isolate and concentrate them. In some cases, the process can involve centrifugation, filtering, and other options to help collect the highest number of stem cells.
The next step is receiving the stem cells, which can take place intravenously, with an injection, as well as other administration techniques.
After you receive the stem cells, your healthcare provider will monitor you to ensure there are no complications. They will also schedule follow-up phone calls to monitor how you are doing post-treatment.
Most people can get right back to their daily activities with some minimal post-treatment guidelines without having to worry about long recovery times.
Available Stem Cell Treatments
How does stem cell therapy work & what are the available treatments? Stem cells can help treat a variety of conditions. It’s helpful in treating cartilage regeneration and osteoarthritis because the stem cells can differentiate into chondrocytes, which are cells that maintain cartilage.
It’s also an option that can help with scar reduction and wound healing. For this procedure, stem cells derived from fat cells are a good option. They can help with tissue regeneration, potentially leading to healing chronic wounds and even the prevention of scarring.
Stem cell therapy is also a good choice for neurodegenerative issues. It can help replace neurons and provide neuroprotective benefits, potentially leading to slowing down the disease’s progression.
Stem cell therapy may also target ligament and tendon injuries, which are common in people who are very active. This type of therapy can help speed up the recovery process and might even be able to prevent the development of chronic pain issues that can affect mobility.
Another way stem cell therapy is able to help is by treating autoimmune diseases. Most autoimmune diseases are impacted by inflammation, so an option like stem cell therapy, which helps reduce swelling, can be helpful.
Choosing Stem Cell Therapy for Lasting Results
Stem cell therapy offers hope for the treatment of many types of conditions. By targeting the cause of pain and chronic injuries, like inflammation, you can avoid relying solely on pain medications, which only mask symptoms. Stem cell therapy makes it possible to have available options to help manage orthopedic injuries, neurodegenerative conditions, and much more.
If you want to learn more about how does stem cell therapy work and not sure whether stem cell therapy is a good option for your needs, speak with a regenerative medicine specialist. They can let you know if you are a good candidate.
by Stemedix | Nov 13, 2023 | Stem Cell Research, Alzheimer’s Disease, COPD, Parkinson's Disease, Regenerative Medicine, Stem Cell Therapy
Regenerative medicine using stem cell therapy has grown in popularity in the past years because of the promising results it has shown for the management of conditions, injuries, and other issues.
By understanding the power of stem cells, the options available, and the reasons why some people are hesitant while others urge research forward, you can decide for yourself whether they are the appropriate treatment option for you.
What Are Stem Cells, and How Do They Help?
Stem cells are undifferentiated cells with the potential to become and create specialized cells. They function as a repair system for the body, contributing to the process of tissue regeneration while also supporting normal growth and development.
Stem cells have two crucial and unique abilities: pluripotency and self-renewal. Pluripotency is the ability to become any kind of cell needed, and self-renewal refers to the way they can replicate themselves indefinitely, providing a never-ending supply of undifferentiated cells.
Different Types of Stem Cells
There are three broad categories of stem cells: embryonic stem cells, adult stem cells, and induced pluripotent stem cells. Each option has diverse applications and unique characteristics.
Embryonic cells come from blastocyst-stage embryos, which are embryos that are from three to five days old. They usually derive from in vitro fertilization clinics. At this stage, the embryo contains an inner cell mass capable of creating all of the tissues that make up the human body. Embryonic cells are fertilized in a lab and donated with full consent. But due to ethical controversy, it is widely used in research only.
Adult stem cells are found in various tissues and organs throughout the adult human body. These stem cells are multipotent, so they can transform into a limited number of stem cells. Adult stem cells help maintain tissue homeostasis and repair and replace damaged cells.
Adult stem cells include:
- Mesenchymal stem cells
- Blood stem cells
- Skin stem cells
- Neural stem cells
- Epithelial stem cells
Induced pluripotent stem cells are made by reprogramming certain adult stem cells into a pluripotent state with the use of genetic factors. These cells are similar to embryonic stem cells in the way they function.
Stem Cell Research: Why There’s Controversy
Using stem cells and performing stem cell research still poses challenges in ethics for some people, especially when turning to embryonic stem cells.
Concerns over when personhood begins make the use of embryonic stem cells more complex because there’s a worry about the moral status of embryos and whether they can be used or discarded.
It’s crucial to understand that the embryos that are used have never been in a woman’s body. They are embryos that fertility clinics would otherwise discard. Although the discarding of the embryos is not usually a controversy, the use of those same embryos for research creates controversy for some.
In this regard, induced pluripotent stem cells are more readily accepted because they don’t rely on embryos. Other issues can arise, however, when it comes to the actual process of researching stem cells. This includes oversight concerns as well as consent issues.
Arguments for Stem Cell Research
Because of the benefits that stem cell therapy offers, many scientists encourage research to improve treatments and learn more about how human bodies function.
Scientific Advancements
Stem cell research contributes to the understanding of cellular processes. This allows for the development of better treatment options, as well as a better comprehension of how some conditions form. Stem cells hold promise for the treatment of degenerative conditions like Parkinson’s disease, COPD, and Alzheimer’s.
Additionally, stem cell research offers the chance for scientists to understand how stem cells replace or repair damaged cells. This information would make it easier to provide targeted treatments that are more efficient and longer lasting.
Economic Boost
Using stem cells to create new therapies and medical technologies opens the door to the creation of new jobs and specializations. These advanced treatments can also help decrease medical costs, helping the economy in the long run.
Ethical Use of Discarded Embryos
Embryos that have been made via in vitro fertilization processes and have gone unused can serve a purpose instead of being discarded. Many argue that this is a better option than treating the embryos like medical waste.
Arguments Against Stem Cell Research
Those against stem cell research generally cite safety and ethical concerns centering on consent and exploitation problems.
Safety and Efficacy
Because stem cell therapies are still relatively new, there are worries about how effective they can be. The issue with this argument against stem cell research is that it fights against the very thing that would provide a definite answer as to whether stem cells are effective and safe: ongoing research.
Ethical Concerns
The ethical concerns mainly focus on the use of embryonic stem cells, including the worry about obtaining consent. In many instances, detractors suggest turning to induced pluripotent stem cells for research and avoiding embryonic cell use because of the ethical barriers that would slow the research down.
In other instances, the worry of consent focuses on the risk of the potential exploitation of vulnerable populations. Those against the research note concern about the possibility of future coercion and other similar activities.
However, as with any other form of research, the scientific community imposes strict guidelines designed to protect against these concerns.
Focusing on the Potential of Regenerative Medicine
Living with chronic conditions that affect quality of life usually means relying on medications, invasive procedures, and therapies that might manage some symptoms but don’t get to the root of the problem.
On the other hand, stem cell research offers the potential to not only understand the causes of some of the most debilitating conditions and injuries, but also to provide therapy solutions to help manage symptoms.
The path to learning more about conditions like COPD or Parkinson’s is not easy, but embracing new and promising treatment options can open a way forward. By tackling some of the ethical concerns people have about stem cells head-on, lives may be able to improve for many people around the world.
by Stemedix | Oct 16, 2023 | Parkinson's Disease
Parkinson’s disease is a complex neurological disorder. It can affect many aspects of your life and wear down your mental health. Fortunately, there are now modern treatment options that help you manage your Parkinson’s symptoms.
If you’ve just received a Parkinson’s diagnosis, don’t give up hope. Learn more about your treatment options so you can live your life to the fullest, regardless of your diagnosis.
How Parkinson’s Symptoms Affect Daily Living
You’ve probably heard of the most common symptoms of Parkinson’s. They can make daily tasks feel more challenging and inaccessible. As Parkinson’s disease progresses, if there is no medical intervention, symptoms tend to worsen.
Motor Symptoms: Trouble with Normal Movements
Parkinson’s disease is related to the amount of dopamine in your brain. When your brain cells stop producing the correct amount of dopamine, your movements change. You no longer have smooth, controlled movements. You may experience shaking, tremors, and slowed motor skills.
Someone with Parkinson’s may have trouble lifting, bending, twisting, or even walking. In the later stages of this disease, Parkinson’s can cause complete immobility, necessitating wheelchair assistance.
If you can’t move around properly, you can’t carry out many normal daily tasks. Cooking, cleaning, and self-care have become nearly impossible.
Digestive Health and Gastrointestinal Problems
Changes in your brain from Parkinson’s disease can lead to problems with digestion. You may experience constipation, bloating and indigestion, and urinary incontinence. Gastrointestinal changes can make eating a less positive experience for Parkinson’s patients.
Mood and Personality Changes
As with any neurodegenerative disorder, Parkinson’s disease can cause mood changes. You may not recognize what’s happening to your mental state. Unfortunately, this is an expected symptom of this neurodegenerative disease.
Parkinson’s patients may experience increased irritability, suspicion, confusion, and depression. These mood changes make it harder to get along with other people. You may start to feel like a different person altogether.
Personality changes can impact your social relationships, which are essential for human health and connection. With the rise in stem cell therapy treatments for Parkinson’s, however, there is hope for getting back to your former self.
Why Early Treatment Is So Important
Getting Parkinson’s disease treated early is essential to slowing the progression of this disorder. The earlier you catch Parkinson’s, the better your outcome will be. Since this is a neurodegenerative disorder, time spent untreated can worsen your symptoms.
If you have just received a diagnosis, now is the time to start looking into your treatment options. What’s out there for you? Is there hope? The answer is yes.
What Are Your Treatment Options?
Modern science and research have allowed medical providers to help slow the progression of Parkinson’s disease. Treatment options include various therapies to help you regain your speech and motor skills. Other innovative treatments, like regenerative medicine, help manage the condition by repairing tissues to improve your health.
Changing Your Lifestyle
Lifestyle changes can have surprising effects on your overall health. Certain parts of your lifestyle may be contributing to worsening health. These can include smoking, under exercising, and overeating.
When you receive a Parkinson’s diagnosis, it’s important to take your health seriously. Getting plenty of sleep and nutrition will help you feel your best each day. You should also quit smoking and give up other harmful habits, like excessive snacking on junk food.
You can protect your health by including healthier habits in your daily routine. Lifestyle changes alone may not cure Parkinson’s, but they can improve your quality of life.
Occupational, Speech, and Motor Therapy
You can opt for speech, motor, or occupational therapy to improve your skills in daily life. These therapies are designed to restore daily functioning in ways that promote independence. If you struggle with your current tasks, this may be a good option for you.
Certified therapists will help you gain new skills that assist with movement, speech, and performing tasks. A Parkinson’s diagnosis doesn’t mean you’re doomed. With the right types of therapy in your life, you can achieve a higher level of function.
Regenerative Medicine with Regenerative Properties
Regenerative medicine, also known as stem cell therapy, utilizes mesenchymal stem cells (MSCs). MSCs are multipotent stem cells that can be isolated from various tissues, such as bone marrow, adipose tissue, and umbilical cord, and they possess several beneficial properties.
MSCs hold promise as a potential therapeutic approach for Parkinson’s disease. This condition is characterized by the loss of dopaminergic neurons in the brain. MSCs have been studied for their ability to modulate inflammation, promote neuroprotection, and stimulate endogenous repair mechanisms in the brain.
MSCs have shown the potential to improve motor function, reduce neuroinflammation, and promote the survival and differentiation of existing neurons. Additionally, MSCs can secrete neurotrophic factors and anti-inflammatory molecules, which may contribute to their therapeutic effects.
When it comes to Parkinson’s disease treatment options, stem cell therapy may be one to explore as a potential therapy in conjunction to others. Some patients experience improvements in their speech, cognition, and motor skills after stem cell treatments.
What to Expect from Stem Cell Therapy for Parkinson’s
Scientists have not yet found a cure for Parkinson’s disease. However, with appropriate stem cell therapy, we may be able to slow the progression of this disorder. Here are some results you can expect from consistent stem cell treatments for Parkinson’s.
More Energy
Stem cell treatments have given our patients more energy and less fatigue. You want to enjoy your life to the fullest. Why not enjoy an extra energy boost from the regenerative powers of stem cell therapy?
Reduced Tremors and Shaking
Tremors are an inconvenient symptom of Parkinson’s disease. Certain stem cell treatments may reduce the frequency of your tremors and shaking. Arm and leg movements would then be easier and less stressful. You may find that your coordination also improves.
Better Cognition and Memory
Parkinson’s unfortunately affects the way you think and how much you can remember. Some patients have seen marked cognitive improvement after stem cell treatments. This is likely because stem cells have the power to regenerate damaged brain cells and improve overall mental functioning.
More Fluid Movements
Stiffness and inflexibility come with Parkinson’s disease. Through stem cell therapy, you may be able to achieve more fluid movements.
Managing Your Parkinson’s Diagnosis with Hope
With a Parkinson’s diagnosis, you do have options to explore. Through traditional and innovative treatments like stem cell therapy, science may be able to help you reverse or slow the progression of this disease. Patients can have the potential to manage their condition and possibly help improve their daily life and activities.
by Stemedix | Jul 31, 2023 | Mesenchymal Stem Cells, Parkinson's Disease, Regenerative Medicine, Stem Cell Therapy
What is Post Stroke and How is it Diagnosed?
“Post-stroke” or “post-stroke period” refers to the period of time following a stroke. A stroke occurs when there is a sudden disruption of blood flow to a part of the brain, leading to brain cell damage and, potentially, the death of brain tissue. The severity and specific consequences of a stroke depend on various factors, such as the type of stroke (ischemic or hemorrhagic) and the location and size of the affected brain area.
The post-stroke period is a critical time for stroke survivors as they begin their recovery and rehabilitation journey. During this period, individuals may experience a range of physical, cognitive, emotional, and social challenges. The post-stroke phase can vary in duration and intensity depending on the extent of brain damage and the effectiveness of treatment and rehabilitation.
Some common aspects and challenges of the post-stroke period include:
Medical stabilization: In the immediate aftermath of a stroke, medical professionals focus on stabilizing the patient, preventing further damage, and addressing any potential complications.
Acute care and rehabilitation: Once the individual’s condition is stable, they may undergo rehabilitation, which may involve physical therapy, occupational therapy, speech therapy, and other specialized treatments to help restore lost functions and improve independence.
Physical recovery: Many stroke survivors experience weakness, paralysis, or difficulty with mobility. Physical therapy aims to help them regain strength, balance, and coordination.
Cognitive recovery: Depending on the area of the brain affected, stroke survivors may experience difficulties with memory, attention, language, and problem-solving. Cognitive rehabilitation can assist in addressing these issues.
Emotional and psychological support: Stroke can have significant emotional and psychological impacts. Depression, anxiety, and frustration are not uncommon during the post-stroke period.
Social reintegration: Stroke survivors may face challenges in reintegrating into their communities and resuming their daily activities. Support from family, friends, and support groups can be essential during this phase.
Long-term management: For some individuals, the effects of a stroke may be permanent, necessitating ongoing care and management of any residual disabilities or health issues.
The post-stroke period is highly individual, and recovery outcomes can vary widely from person to person. Early intervention, rehabilitation, and ongoing support play vital roles in improving the quality of life for stroke survivors.
Diagnosing a stroke typically involves a combination of clinical evaluation, medical history assessment, and imaging tests. Rapid and accurate diagnosis is crucial because time is of the essence when it comes to stroke treatment.
The faster a stroke is diagnosed and treated, the better the chances of minimizing brain damage and improving outcomes.
What Are The Different Types of Stroke?
There are two main types of strokes: ischemic stroke and hemorrhagic stroke. Each type has different underlying causes:
Ischemic Stroke:
Ischemic strokes account for about 85% of all strokes and occur when there is a blockage or narrowing of a blood vessel supplying blood to the brain. This blockage can be due to a blood clot (thrombus) that forms within a blood vessel in the brain (cerebral thrombosis) or elsewhere in the body and travels to the brain (cerebral embolism).
Common risk factors for ischemic stroke include atherosclerosis (the buildup of fatty deposits in the blood vessels), high blood pressure (hypertension), diabetes, high cholesterol levels, smoking, and certain heart conditions such as atrial fibrillation.
Hemorrhagic Stroke:
Hemorrhagic strokes occur when a blood vessel in the brain ruptures, causing bleeding into or around the brain tissue. The bleeding puts pressure on brain cells and can damage them.
The two main types of hemorrhagic stroke are intracerebral hemorrhage (bleeding within the brain) and subarachnoid hemorrhage (bleeding into the space between the brain and the thin tissues that cover it).
Hypertension is a significant risk factor for hemorrhagic stroke, as it can weaken blood vessel walls over time. Other risk factors include brain aneurysms, arteriovenous malformations (AVMs), and certain blood-thinning medications.
How Can I Avoid a Potential Stroke?
It’s important to note that certain lifestyle factors and medical conditions can increase the risk of stroke. These include:
- Sedentary lifestyle
- Poor diet (high in saturated fats, salt, and processed foods)
- Obesity
- Excessive alcohol consumption
- Illicit drug use, especially cocaine and amphetamines
- Heart disease
- Family history of stroke or cardiovascular disease
- Age (stroke risk increases with age)
- Gender (men have a slightly higher risk)
- Race and ethnicity (some groups, such as African Americans and Hispanics, have higher stroke risk)
Managing risk factors through lifestyle changes and medical treatment can significantly reduce the likelihood of experiencing a stroke.
How Do You Know If You Are Having or Have Had a Stroke?
If you suspect someone is having a stroke or experience symptoms yourself, it’s crucial to seek immediate medical attention as prompt treatment can minimize brain damage and improve outcomes. Remember, “FAST” is a simple way to remember the most common symptoms of a stroke:
F – Face drooping
A – Arm weakness
S – Speech difficulty
T – Time to call emergency services.
Recognizing the symptoms of a stroke is crucial because immediate medical attention can greatly improve the chances of minimizing brain damage and improving outcomes. The symptoms of a stroke can vary depending on the type of stroke (ischemic or hemorrhagic) and the part of the brain affected.
Here are some common signs and symptoms of a stroke:
Sudden numbness or weakness: You may experience sudden numbness or weakness in the face, arm, or leg, typically affecting one side of the body. A common indicator is drooping on one side of the face when trying to smile.
Trouble speaking or understanding speech: You might have difficulty speaking coherently or understanding what others are saying. Your speech may become slurred or difficult to comprehend.
Confusion or trouble with comprehension: You may feel confused, disoriented, or have difficulty understanding simple instructions or questions.
Sudden severe headache: A sudden, severe headache that is different from any previous headaches you’ve experienced may be a warning sign of a stroke, especially if it’s accompanied by other symptoms.
Trouble with vision: You may experience sudden blurred or double vision or have trouble seeing out of one or both eyes.
Dizziness or loss of balance: You may feel dizzy, lightheaded, or have trouble maintaining your balance, leading to difficulty walking or coordination problems.
hemorrhagic strokes) to prevent further damage to the brain. Rehabilitation and support following a stroke are also essential for recovery and regaining function.
What Treatments Are There for Post Stroke Care?
Post-stroke care focuses on the rehabilitation and management of stroke survivors to improve their physical, cognitive, emotional, and social functioning. The specific treatments for post-stroke care depend on the individual’s needs and the extent of the stroke’s impact. Here are some common components of post-stroke care and treatments:
- Physical therapy
- Occupational therapy
- Speech therapy
- Cognitive rehabilitation
- Emotional support and counseling
- Medications
- Pain management
- Assistive devices
- Nutritional support
- Social and vocational support
Post-stroke care is often a multidisciplinary approach, involving a team of healthcare professionals working together to develop a personalized treatment plan. The goal is to maximize the individual’s functional recovery, promote independence, and enhance their overall quality of life after a stroke. As each stroke survivor’s situation is unique, the treatment plan will be tailored to their specific needs and abilities. Regular follow-up appointments and ongoing support are essential components of post-stroke care to monitor progress and adjust treatment as necessary.
Regenerative Medicine for Post Stroke Management
Regenerative medicine, also known as stem cell therapy, is a cutting-edge field of medicine that focuses on harnessing the regenerative capabilities of stem cells to treat various medical conditions and injuries, including post-stroke care.
Mesenchymal stem cells (MSCs) are unique cells that have the ability to differentiate into different cell types and self-renew, meaning they can produce more stem cells. MSCs are a type of adult stem cell found in various tissues, such as bone marrow and adipose (fat) tissue. They have the unique ability to differentiate into different cell types and secrete bioactive molecules that can promote tissue repair and modulate the immune response.
In the context of post-stroke care, MSC therapy aims to harness the regenerative and immunomodulatory properties of these stem cells to potentially enhance neurological recovery and reduce post-stroke complications.
Several preclinical studies and early-phase clinical trials have investigated the safety and potential benefits of MSC therapy for stroke. Here are some potential ways MSCs might exert beneficial effects in post-stroke patients:
- Neuroprotection: MSCs have been shown to secrete factors that protect neurons from further damage and promote cell survival in animal models of stroke.
- Anti-inflammatory effects: After a stroke, inflammation in the brain can exacerbate damage. MSCs can modulate the immune response, reducing harmful inflammation and promoting a more favorable environment for recovery.
- Angiogenesis: MSCs can support the formation of new blood vessels (angiogenesis) in damaged brain tissue, improving blood flow and oxygen supply to the affected areas.
- Neuroplasticity: MSCs may help enhance brain plasticity, which is the brain’s ability to reorganize and form new neural connections, potentially aiding recovery and functional improvements.
If you or someone you know is interested in exploring this alternative medicine, work with a regenerative medicine specialist who can help provide detailed information about the options available to them.
by admin | May 12, 2023 | Health Awareness, Parkinson's Disease
Exercise and a healthy diet are two of the most potent treatments for Parkinson’s disease. Many people who live with Parkinson’s find that positive lifestyle changes slow the condition’s progression and give them better control over their symptoms.
Exercise and Parkinson’s Disease
Exercise is universally beneficial and can improve anyone’s overall health. However, those with Parkinson’s might discover these specific benefits:
- Preventing or slowing the disease’s progression
- Improving brain health
- Reducing symptoms like loss of balance or constipation
- Avoiding isolation
Nobody should have to slog through a workout they hate. Fortunately, all forms of exercise can benefit those with Parkinson’s. The best physical activities are the ones you enjoy — as long as your healthcare provider approves.
Diet and Parkinson’s Disease
Patients can manage some symptoms of Parkinson’s through targeted nutrition. In general, consuming a plant-based diet that includes whole foods offers significant benefits in reducing some of the challenges of the disease.
Although there isn’t a specific diet for Parkinson’s disease, patients should prioritize eating whole grains, fruits and vegetables, protein, and healthy fats to boost their overall health.
Water and Fiber for Constipation
Parkinson’s can lead to digestive concerns, including constipation. However, drinking six to eight glasses of water daily and eating high-fiber foods can support regular digestion.
Limit Sugar and Caffeine for Better Sleep
Researchers estimate that two-thirds of Parkinson’s patients struggle to get adequate sleep. Limiting your intake of sugar, caffeine, and alcohol can promote better sleep quality.
Eat Nuts and Berries for Brain Health
Healthy fats found in nuts and beneficial antioxidants from berries can promote brain health and provide anti-inflammatory benefits. Other foods to fortify your brain include fish like salmon and green leafy vegetables like spinach and kale.
More Water for Medication Absorption
Many Parkinson’s medications can cause dehydration. Over time, dehydration can exacerbate symptoms like confusion, kidney problems, and balance issues. Get into the habit of drinking a full glass of water with your medications so that your body breaks them down more efficiently.
Changing your diet and exercise routine can be difficult. Ask your physician for advice, and start with small changes instead of a complete overhaul of your habits for lasting results.
St. Petersburg, Florida
