A recent publication in BioMed Research International has reviewed the study on the potential benefits of Wharton’s jelly derived mesenchymal stem cells in treating a variety of diseases. According to the authors of the review, these stem cells can be collected during millions of births each year at the time of delivery. A huge advantage of this…
Ease of Use and Therapeutic Applicability of Wharton’s Jelly-Derived Mesenchymal Stem Cells Posted August 21, 2018 and filed under Stem Cell Therapy, Wharton's Jelly. Mesenchymal stem cells have been showing promise in the treatment of a variety of diseases and injuries. These cells are derived from different tissue types, and it appears that where the…
Wharton’s jelly is a rather unique body fluid. It is the connective tissue found within the umbilical cord. While Wharton’s jelly is connective tissue, it more closely resembles gelatin. Historically this material was discarded as medical waste; however, Wharton’s jelly has been shown to contain a number of therapeutic substances. Among these healing substances found…
Understanding the Condition Duchenne muscular dystrophy, often called DMD, is a genetic muscle disorder that mostly affects boys. It is caused by changes in the gene responsible for producing dystrophin, a protein that helps keep muscles strong and stable. When the body doesn’t make enough functional dystrophin, muscles become more fragile over time. This can…
Understanding Diabetic Foot Ulcers Diabetic foot ulcers are one of the most serious complications of diabetes. These chronic wounds can be difficult to heal because diabetes may affect circulation, nerve function, immune response, and the body’s natural repair process. When wounds remain open for long periods of time, they can increase the risk of infection,…
Mesenchymal stem/stromal cells (MSCs) continue to be viewed as a source of cell therapy applications due to their immunomodulatory and anti-inflammatory effects and because of their ability to stimulate angiogenesis. In MSCs, these benefits are mainly attributed to the secretion of factors. Despite MSCs’ known and favorable proliferation levels, multipotency, and immune response regulation, there…
Human umbilical cord Wharton’s Jelly derived mesenchymal stem cells (WJ-MSCs) are reported as the most potent cell source of MSCs, however, they remain understudied in comparison to other autologous sources of MSCs. Mehling et al.’s study aimed to evaluate the safety of WJ-MSC therapy for a range of conditions and administration routines, including intravenous, intrathecal,…
Mesenchymal stem cells (MSCs) are multipotent fibroblast-like cells found throughout the body and have been found to have self-renewing and multilinear therapeutic potential by providing new cells for tissue repair by replacing damaged cells. Thought to stimulate repair and control the immune response through an expression of growth factors and other cytokines, MSCs are at…
Articular cartilage, found on the surface of most regenerative medicine for musculoskeletal injuries joints, distributes and transfers forces between bones and joints, provides a smooth surface for joint mobility, and plays an important role in human mobility. However, articular cartilage is also easily susceptible to damage, but difficult to repair itself on its own (primarily…
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