Do you suffer from aches and pains due to rheumatoid arthritis (RA)? The stiffness caused by RA is a nuisance for many patients and it is especially prevalent in the morning. When you awake from even the most comfortable of sleep, your joints may feel painful and stiff for several hours. How can this be avoided?
4 Ways to Reduce Morning Stiffness for RA Patients
Most patients turn to over-the-counter pain medications to ease their RA morning stiffness, but there may be some other alternatives. The following are four ways to reduce rheumatoid arthritis stiffness and start your day off right.
1. Turn Up the Heat
Experts suggest turning your heat up about 30 minutes before you plan to start your day. This will allow time for your joints to warm up and feel less stiff while you take it easy and relax in bed or have your morning coffee. By the time you need to get ready and head out the door, your body will feel more relaxed, and stiffness may be decreased.
2. Take Medication as Soon as You Wake Up
While you’re turning up the heat, go ahead and take any of your rheumatoid arthritis medications. You want to give your medication time to kick in and take effect before you begin your morning routine. This will help ease most of the aches and pains that you may feel in your joints during morning activities.
3. Practice Gentle Movements
Once you are ready to get out of bed, practice gentle movements rather than jumping to your feet and rushing around the house. Simple range-of-motion exercises can help stretch your muscles and loosen joints in the hands, wrists, and feet.
4. Take A Hot Shower
While many people opt for nighttime showers, RA patients may benefit from taking a hot morning shower. Taking a warm shower upon waking in the morning will help loosen and relax the joints, decreasing any stiffness or aching.
If you suffer from chronic pain from your rheumatoid arthritis, you may want to explore how regenerative medicine, also known as stem cell therapy, may help manage symptoms. In addition, some patients are discovering help from peptides. These are chains of amino acids, and some may have the potential for those with chronic pain. Alternative medicine does not offer a cure, but for some, it may help improve quality of life.
There are a number of things that can cause arthritis, a painful condition that causes stiffness in joints. In Rheumatoid Arthritis (RA), the body’s immune system attacks the musculoskeletal system, causing inflammation that leads to arthritis pain. Over time, RA can cause a number of problems, including cartilage deterioration, swelling, and excess synovial fluid at the joint. In this article, we talk about how Stem Cell Therapy can help to treat Rheumatoid Arthritis.
Using Stem Cell Therapy to Treat Rheumatoid Arthritis
Because RA is a chronic condition, there is no cure. This means that treatment focuses on preventing attacks and easing symptoms. While there are medications that can help to tamp down the autoimmune response that causes RA pain, symptom management tends to rely on medication to relieve pain, which can be difficult to moderate.
Instead, some patients are seeking out stem cell therapy. Stem cells have the ability to differentiate into other cell types. By administering mesenchymal stem cells (MSCs) systemically and directly to problematic joints, it may potentially help to regrow cartilage tissue and ease pain from rheumatoid arthritis.
How Stem Cell Therapy Can Benefit RA Patients
By taking a different approach to the treatment of RA, stem cell therapy offers potential relief that traditional treatments have not been able to provide to patients, including:
Because stem cells are able to differentiate into other cell types, they can be particularly useful for patients suffering from RA. When these stem cells are injected into a joint, they can help to rebuild the cartilage that cushions joints, counteracting the damage from RA.
Stem cells also have the potential to help regenerate other damaged tissues as well, including the synovium tissues, which help lubricate joints to keep them from becoming inflamed.
Regulating the Autoimmune Response
Stem cells have shown to be safe and promising in helping reduce the inflammatory response that results from the autoimmune attacks behind RA. Stem cell therapy has been used in the treatment of other autoimmune diseases, including Crohn’s disease and multiple sclerosis, and it shows promise for RA, as well. So yes, Stem Cell Therapy can help to treat Rheumatoid Arthritis.
Reducing Further RA Damage
Stem cell therapy offers the possibility of reducing further RA attacks on joints that may not yet be affected by the disease. With the potential to limit the autoimmune responses that cause RA damage and to instead encourage healing and tissue growth, stem cells may be able to slow the impact of rheumatoid arthritis. This may allow patients to experience less pain and preserve their quality of life. If you would like to schedule an appointment to treat your RA, contact a care coordinator today!
Arthritis is characterized by inflammation in the joints, which often causes pain, stiffness, and swelling. The levels of inflammation in your body are influenced by a number of factors, including diet. Some foods in particular have been shown to increase inflammation, thus exacerbating arthritis symptoms. To help control your arthritis, here are some foods to limit or avoid.
The oil used for frying often contains omega-6 fatty acids, which have been linked to increased inflammation. Because they’re associated with a number of other health issues, including heart problems, they’re best avoided altogether.
Salt is found in many different foods, but it’s important for people with arthritis to control their consumption. The mineral can increase the body’s inflammatory response, and it’s also been associated with an elevated risk of rheumatoid arthritis (RA). Flavor your food with joint-healthy seasonings, such as cumin, ground pepper, or garlic powder, instead.
Added sugars have a broad range of health risks, ranging from their association with obesity and type 2 diabetes to elevated inflammation. Even low to moderate intake of sugary drinks such as sodas, juices, and sweet teas has been linked to heightened inflammation. If plain water seems too bland, considering adding a fresh wedge of lemon or cucumber slices to give it some flavor.
Moderate alcohol intake can reduce inflammation in certain types of arthritis. For instance, the antioxidants in red wine help to promote joint health in RA with a daily five-ounce serving. Yet, alcohol can also trigger symptoms in other types of arthritis, including gout. If you’re unsure about how drinking could affect your arthritis, it’s best to talk to your rheumatologist.
Red meat is notoriously high in saturated fat, which has been linked to inflammation that leads to joint swelling. Other types of protein, including plant-based sources and poultry, are lower in saturated fats, and thus better for joint health.
High-Fat Dairy Products
Like red meat, full-fat dairy products, including cheese, yogurt, and milk, have high levels of fat. They also typically contain more added sugars than low-fat varieties. Some people with arthritis eliminate dairy from their diets altogether to reduce its inflammatory effects, while others enjoy low-fat options. Low-fat yogurt, in particular, may be worth keeping in your diet, as it contains probiotics which can actually help control inflammation.
Heavily Processed Foods
Heavily processed foods such as refined carbohydrates, candy, lunch meat, and baked goods often have additives that contribute to inflammation. Many are loaded with added sugars or excess salt, and can therefore aggravate arthritis symptoms. Whenever possible, choosing primarily whole foods such as fruit, vegetables, healthy fats, and lean protein, will be best for controlling inflammation and arthritis symptoms.
Rheumatoid arthritis (RA) is a chronic inflammatory condition in which the immune system attacks healthy joint tissue. This abnormal immune response leads to inflammation, fluid buildup, swelling, and discomfort in the joints. RA is a chronic condition for which there is no cure, and due to the progressive nature of the disease, symptoms often worsen over time.
Current treatments for RA involve controlling the immune response to prevent further damage and alleviating joint pain. Yet, oftentimes, existing therapies fail to mitigate the damage joints have already sustained. Some research has been finding that there may be potential therapeutic effects with regenerative medicine, also known as stem cell therapy for Rheumatoid Arthritis.
Stem Cell Therapy for Rheumatoid Arthritis
Stem cells are the building blocks of virtually all specialized cells and tissue in the body. They can transform into many different cell types, and have regenerative and anti-inflammatory properties. Medical researchers have been exploring ways to leverage these powerful cells to help manage symptoms for autoimmune conditions, including Rheumatoid Arthritis.
As the cartilage between bones becomes inflamed and wears away, the joint and surrounding bone can become damaged, too. Mesenchymal stem cells (MSCs) can develop into bone and cartilage tissue, and when isolated and injected into affected joints, could help repair damage caused by RA.
Since RA is an inflammatory disease, it can lead to health issues beyond joint damage. Systemic inflammation, fever, weight loss, muscle weakness, and diseases of the heart and lungs can also occur over time. For this reason, combatting the widespread inflammation that occurs with the disease is critically important. According to research, MSCs can control inflammation by increasing regulatory T cells (RTCs), which help to prevent the immune system from attacking healthy tissue.
Additional study results have shown significantly lower levels of blood markers which indicate RA at one- and three-year intervals after stem cell therapy. In these trials, patients received intravenous infusions of MSCs to treat the systemic inflammation associated with RA. In addition to reduced body-wide inflammation, patients also experienced a reduction in symptoms and improvements in physical function.
Although there still has yet to be a definitive cure for RA, stem cell therapy has been researched as a potential option to:
Reduce joint inflammation and stiffness
Increase range of motion
Improve energy levels and reduce fatigue
Minimize joint pain and swelling
For patients interested in exploring new treatment options, MSCs may enhance a patient’s quality of life and alleviate some of the condition’s most debilitating symptoms. Contact a Care Coordinator today for a free assessment!
Rheumatoid arthritis causes chronic inflammation of multiple joints throughout the body. This joint inflammation eventually causes the cartilage and bone to break down, and the tendons and ligaments surrounding the joints stretch and become deformed. Consequently, people with rheumatoid arthritis experience pain and loss of function in affected joints.
Unfortunately, rheumatoid arthritis is not just a disease of joints. Rheumatoid arthritis also causes systemic inflammation. People with rheumatoid arthritis commonly experienced fevers, weight loss, and chronic fatigue. Many patients report being achy or stiff apart from joints directly affected by arthritis. Rheumatoid arthritis can cause bone loss, muscle weakness, skin lesions, and kidney disease. Patients may also experience lung, heart, and vascular diseases.
The cause of rheumatoid arthritis is unknown; however, since it is an inflammatory disease, the main treatment for rheumatoid arthritis is an anti-inflammatory medication. Some lifestyle changes may help to ease some of the symptoms but most physicians initially recommend using a disease-modifying antirheumatic drug or DMARD soon after rheumatoid arthritis is diagnosed. DMARDs can modestly reduce symptoms of rheumatoid arthritis and help reduce the risk of patients developing debilitating joint abnormalities. DMARDs include drugs such as methotrexate or biologics such as infliximab or tofacitinib. Patients with rheumatoid arthritis usually also must take glucocorticoids, i.e. steroids to acutely control inflammation. Unfortunately, these agents have considerable side effects, especially when taken for long periods of time. Moreover, the treatments are not curative. As such, researchers are still looking for better treatments for rheumatoid arthritis.
Scientists recently conducted a prospective Phase 1/2 study of umbilical cord mesenchymal stem cells in patients with rheumatoid arthritis. They selected 64 patients with rheumatoid arthritis between the ages of 18 and 64. Volunteers received an intravenous infusion of mesenchymal stem cells and were followed for three years. At both the 1 and 3 years follow up appointments, the rheumatoid arthritis patients treated with mesenchymal stem cells had substantially lower levels of the blood markers that indicate rheumatoid arthritis (namely C-reactive protein, elevated erythrocyte sedimentation rate, rheumatoid factor, and anti-CCP antibody). The test of physical function also significantly improved at 1 and 3 years after stem cell treatment [Health Index (HAQ) and Joint Function Index (DAS28)]. The treatment was also safe, and no serious adverse effects were reported.
The results of this stem cell clinical trial are particularly remarkable because patients received only one intravenous treatment and enjoyed at least three years of improvement in their disease both in the blood markers but also in symptoms and physical functioning. Although not a cure, this study shows the apparent safety of mesenchymal stem cell treatment and the impressive benefits to allow patients to consider researching stem cell therapy as an alternative option for their rheumatoid arthritis symptom management. Indeed, if additional larger studies confirm these impressive results, umbilical cord mesenchymal stem cell treatment may become a possible standard of care in the treatment of rheumatoid arthritis in the future.
Reference: Wang L, Huang S, Li S, et al. Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy for Rheumatoid Arthritis Patients: A Prospective Phase I/II Study. Drug Des Devel Ther. 2019;13:4331-4340. Published 2019 Dec 19. doi:10.2147/DDDT.S225613
Rheumatoid arthritis (RA) is a chronic inflammatory condition that can affect the joints, as well as several body systems. As an autoimmune disease, RA is characterized by the body’s immune system mistakenly attacking its own healthy tissue. While other forms of arthritis, such as osteoarthritis, are caused by general wear and tear, RA targets the joint lining, resulting in swelling that will eventually erode the joints and bones.
In some cases, the inflammation can cause widespread damage throughout bodily systems such as the eyes, skin, lungs, heart, and blood vessels. Although there have been treatments available to control the symptoms of RA, in some severe cases, physical disabilities may still occur.
Can Stem Cell Therapy Help Treat Rheumatoid Arthritis?
Typically, RA is treated with immune suppressive medications such as steroids. While they may offer temporary relief, long-term use isn’t advised, as it can suppress the body’s immune response. Thus, such medications leave patients more vulnerable to infections and other illnesses. Disease-modifying anti-rheumatic drugs (DMARDs) may be prescribed as well, or biologics if needed. Nonetheless, these medications fail to address joint damage which has already occurred. Moreover, many patients fail to see significant results.
Recently, stem cell therapy has emerged as a studied and researched option to target inflamed tissue and trigger the development and anti-inflammatory agents. Mesenchymal stem cells (MSCs), in particular, have been shown to produce T regulatory cells, which help to safeguard against the self-attacking immune response seen in RA. One study on MSCs for RA demonstrated a significant decrease in pro-inflammatory agents, absent of the long-term side effects caused by traditional RA therapies.
Which Type of Stem Cells Are Used to Treat Rheumatoid Arthritis?
MSCs are a commonly used stem cell therapy option for managing symptoms of Rheumatoid Arthritis. These cells are derived from either adipose (fat) tissue from the patient or the umbilical cord (Wharton’s Jelly) following healthy births. The mothers undergo rigorous screening to ensure the safety of the cells. Because umbilical cord-derived stem cells are some of the youngest, they have longer cell lives than those derived from adults.
What Are the Benefits of Mesenchymal Stem Cells?
Since they are do not come from the blood, MSCs are considered safe and do not require phenotypic or Hyman Leukocyte Antigen (HLA) matching. Cell rejection is therefore not a concern. Mesenchymal stem cells exert a number of beneficial effects on the cells of the immune system. Mesenchymal stem cells can help fine-tune the immune system by inducing the action of regulatory T-cells potentially shifting the balance from harmful to helpful immune system function.
The benefits of MSCs leave researchers optimistic about the future of stem cells as an option for those with autoimmune conditions such as Rheumatoid Arthritis. The therapy is a worthwhile option to explore for patients seeking potential improvements for their day to day quality of life. Contact a Care Coordinator today for a free assessment!
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