Mesenchymal Stem Cells

Symptoms of Kidney Disease

What is Kidney Disease? Kidney disease, also known as renal disease or nephropathy, refers to a condition in which the kidneys are damaged or unable to function properly. The kidneys play a crucial role in filtering waste products, excess fluid, and toxins from the blood, while also maintaining the body's electrolyte balance and producing important…

Cartilage Repair with Mesenchymal Stem Cells in Osteoarthritis

Osteoarthritis (OA) is the most common and widespread form of arthritis, affecting an estimated 655 million people worldwide. Occurring as a result of cartilage degeneration, OA is a progressive degenerative disorder that most commonly affects the joints of the hands, hips, knees, and spine.   Although OA can affect anyone, it is most commonly observed in…

Adipose Tissue-Derived Mesenchymal Stem Cells and Their Contribution to Tissue Regeneration

Mesenchymal stem cells (MSCs) isolated from a wide variety of tissues and organs have demonstrated immunomodulatory, anti-inflammatory, and regenerative properties that contribute to a host of regenerative and immunomodulatory activities, including tissue homeostasis and tissue repair. The most frequently studied and reported sources of MSCs are those collected from bone marrow and adipose tissue.  In this…

The Effect Of Cigarette Smoke On Mesenchymal Stem Cells And Dental Stem Cells – A Comparison Review

Cigarette smoking continues to be the leading contributor to preventable disease and death in the United States, including cancer, heart disease, stroke, lung diseases, diabetes, and chronic obstructive pulmonary disease (COPD). Smoking cigarettes also increases the risk of tuberculosis, certain eye diseases, and problems of the immune system, including rheumatoid arthritis.   An abundance of clinical…

How Long Does Regenerative Medicine Last for Knees?

A very common question we get is " How long does Regenerative Medicine last for Knees? " for those seeking this alternative treatment for the management of their knee pain. But first, we will discuss what can be behind the knee pain as a cause, who to seek a medical diagnosis, and what options a…

Role of Mesenchymal Stem Cells in Osteoarthritis Treatment

Osteoarthritis (OA) is the most common form of arthritis and is estimated to affect over 500 million people worldwide.  A result of the progressive deterioration of the protective cartilage that cushions the ends of the bones, OA most commonly affects the hands, knees, hips, and spine and is characterized by pain, stiffness, and loss of…

Regenerative Medicine Therapy for Stroke Using Mesenchymal Stem Cells

With nearly 15 million people affected worldwide each year, stroke continues to be the most prevalent cerebrovascular disease. Responsible for over 5 million deaths and another 5 million individuals suffering long-term disabilities, stroke also is the leading cause of mortality and morbidity worldwide.  Although there have been significant advances in both pharmacological and surgical therapies designed…

Mesenchymal Stem Cell Treatment for Ischemic Kidney Disease

Ischemic kidney diseases are serious health issues that lead to irreversible loss of kidney function and are commonly associated with high rates of mortality and morbidity. Many of the conditions captured under the term ischemic kidney disease occur as a result of decreased glomerular filtration rate (GFR) caused by vasoconstriction or loss of autoregulation. Ischemic…

Mesenchymal Regenerative Medicine: A Review of Clinical Trials for Multiple Sclerosis

Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that occurs as a result of the body’s immune system attacking the protective sheath, or myelin, responsible for covering nerve fibers. Characterized by progressive nerve deterioration and damage of the nerve fibers, MS is currently estimated to affect nearly 600,000 adults in…

Exploring the Use of Human Umbilical Cord Mesenchymal Stem Cell-derived Extracellular Vesicles to Improve Airway Inflammation in Cases of COPD

Chronic obstructive pulmonary disease (COPD) is an incurable and debilitating disease characterized by chronic and progressive inflammation that leads to small airway obstruction and emphysema.   According to the World Health Organization, COPD is the third leading cause of death and is responsible for an estimated 3.2 million deaths each year. Between 80 and 90% of…

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