MSC - Page 20

Mesenchymal Stem Cells for Traumatic Brain Injury

Worldwide, an estimated 10 million people suffer some form of traumatic brain injury (TBI) severe enough to result in either death or hospitalization each year. Nearly 20% of these TBIs occur in the United States and over 50,000 of those affected die as a result of their injury.  Characterized by a wide range of physical,…

Regenerative Medicine for Osteoporosis

Developing weak and brittle bones from osteoporosis can lead to mild bone stress — like that from bending over — causing a fracture. Most bone fractures from osteoporosis occur in the wrist, hip, or spine. While there is no cure for osteoporosis, there are treatments and medications that can help strengthen and protect your bones. Here we…

Evaluating The Immunomodulatory Effects of High Dose Intravenous Administration of Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are multipotent fibroblast-like cells found throughout the body and have been found to have self-renewing and multilinear therapeutic potential by providing new cells for tissue repair by replacing damaged cells.  Thought to stimulate repair and control the immune response through an expression of growth factors and other cytokines, MSCs are at…

Mesenchymal Stem Cells and Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and affects an estimated 25% of adults in the United States. Characterized by pain, stiffness, and inflammation in the joints of the body, OA is most frequently observed in the knees, hands, hips, and spine. OA is one of the leading causes of disability with an annual…

A Review of Circulating Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) have been widely used in a number of applications designed to aid in the regeneration and healing of human tissue. Prized for their multipotent capacity to differentiate into a variety of other specific cell types, MSCs have consistently demonstrated the ability to seek out damaged tissue while also reducing inflammation and promoting…

Regenerative Medicine for COPD

Those afflicted with chronic obstructive pulmonary disease (COPD) struggle with persistent respiratory concerns stemming from airflow blockage and lung inflammation. Here we will discuss regenerative Medicine for COPD. The conditions that contribute to COPD, such as emphysema and chronic bronchitis, can cause excess mucus production, frequent coughing, wheezing, or shortness of breath. While treatments including lifestyle…

Mesenchymal Stem Cell-Based Therapy for Type 1 Diabetes

Currently, it’s estimated that nearly 1.5 million Americans are living with type 1 diabetes (T1D), a number that is expected to increase to over 2 million by the year 2040[1].  In the U.S. alone, healthcare costs and lost wages directly related to T1D currently exceed $16 billion per year.   While the most common treatment…

Mesenchymal Stem Cell-Based Therapy For Rheumatoid Arthritis

Mesenchymal stem cells (MSCs) have demonstrated the ability to differentiate into a number of different cells; they also demonstrate immunomodulatory properties that have great potential for use as a stem cell-based therapeutic treatment option and for the treatment of autoimmune diseases - including rheumatoid arthritis (RA). RA is a chronic and debilitating inflammatory disorder that…

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Non-Coding RNA Therapeutic Vehicles in Autoimmune Diseases

The number of people experiencing autoimmune diseases (ADs) continues to increase worldwide. Currently, it's estimated that between 2 and 5% of the global population is afflicted with the most severe forms of these diseases, including type 1 diabetes (T1DM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA).  An autoimmune disease can occur nearly anywhere in…

What Are Adult Stem Cells?

Stem cells are essential in understanding human development, disease, injury, and potential treatments and cures. However, since the initial research on these critical cells began with embryonic stem cells, many people dismiss the benefits of stem cell research and treatment as controversial. Unfortunately, that dismissal ignores what may be of adult stem cells, which are more…

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