by admin | Mar 25, 2022 | Mesenchymal Stem Cells, Neurodegenerative Diseases, Stem Cell Research, Stem Cell Therapy
Neurodegenerative conditions such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) occur when neuron populations begin to diminish. There is currently no cure for these types of diseases, though clinical trials to explore various treatment options are ongoing. In particular, regenerative medicine, also known as stem cell therapy, is being heavily researched and has shown remarkable progress in controlling these conditions.
Types of Stem Cells
Stem cells serve as the foundation for every tissue and organ throughout the body. They are unspecialized but have the incredible ability to differentiate into virtually any cell type, as well as the power to self-renew.
Neurodegenerative conditions are characterized by neurons that progressively lose their function and structure, and eventually die off. Because stem cells are able to differentiate into multiple cell types, researchers have begun exploring whether they could replace or repair damaged neurons to control the progression of, or potentially even reverse the damage done by, these illnesses. Existing treatment options are limited, but many researchers are optimistic about stem cells’ potential.
Not all stem cells are the same. Here are the various types, some of which show more efficacy as a treatment for neurodegenerative disease than others:
- Tissue-specific stem cells: These somewhat specialized stem cells can generate multiple organ-specific cells and are typically located in areas of the body that can self-replenish, such as the skin and blood.
- Embryonic stem cells (ESCs): Located in blastocysts, ESCs are especially promising in neurodegenerative applications. Yet, they do pose some risks, including the risk of rejection. Due to their ability to differentiate into neurons, however, they continue to be studied as a potential therapy.
- Induced Pluripotent Stem Cells (iPSCs): iPSCs are artificially derived from adult cells and programmed back to pluripotency, thereby allowing for an unlimited source of any cell type. While they are widely used for developing medications and disease modeling, further research must be done to refine the reprogramming process.
- Mesenchymal Stem Cells (MSCs): MSCs can differentiate into several types of cells. Their self-renewal capabilities are far-reaching, making them an ideal candidate for therapies involving tissue repair. They may also be leveraged for cell transplantation in the treatment of neurodegenerative diseases.
- Neural Stem Cells (NSCs): NSCs are derived from specific areas of the brain and are therefore specialized cells. They, too, are self-renewing and multipotent.
Types of Neurodegenerative Conditions Regenerative Medicine can Help Manage:
While researchers are uncovering new findings on how stem cells can treat neurodegenerative conditions nearly every day, there has already been progress. Here are some of the conditions stem cell therapy has been used to manage:
- Parkinson’s Disease (PD): One hallmark characteristic of PD is the decline of dopamine, caused by the destruction of dopamine-producing brain cells. As dopamine decreases, symptoms such as muscle tremors, challenges with movement, and difficulty thinking arise. Now, researchers have found that stem-cell-derived dopaminergic neurons — in particular, those created through ESCs and iPSCs — could hold success in replacing the destroyed brain cells in individuals with PD.
- Alzheimer’s Disease: Through the use of stem cell therapy, researchers at Columbia University have refined the protocol for a unique process of converting skin cells into brain cells. This option streamlines the process of creating neurons to replace those which have become damaged by Alzheimer’s disease. In their research, the cells were able to receive signals just as normal neurons would.
- ALS: ALS has proven remarkably challenging to study, as there are many potential causes and therapies may therefore only be effective on specific patient populations. Moreover, the motor neurons, which are directly impacted by the condition, couldn’t be acquired in large enough numbers to study. Now, however, Harvard researchers have been able to derive mature cells that can be manipulated back into stem cells from ALS patients, opening up new doors for studying potential therapies to treat the condition.
While there is more ground to cover before stem cell therapy for neurodegenerative conditions can become mainstream, promising research is consistently being published. Moving forward, it’s likely that stem cells will hold the answer to viable management options for these and other challenging conditions.
by admin | Mar 23, 2022 | Health Awareness, Multiple Sclerosis
The neurodegenerative condition known as multiple sclerosis (MS) causes chronic inflammation within the central nervous system. For decades, clinicians and researchers have tirelessly studied MS to understand the condition better and develop more effective treatments.
Recently, researchers from the Harvard T.H. Chan School of Public Health concluded a study that examined the link between the Epstein-Barr virus (EBV) and multiple sclerosis. They found “compelling evidence of causality” between EBV and MS.
Researchers analyzed data from over 10 million active-duty U.S. military personnel during the study. Of these participants, 955 received an MS diagnosis while serving.
Researchers reviewed serum samples that were collected biennially in order to check for the presence of EBV. As a result of the study, researchers discovered that soldiers were 32 times more likely to develop MS after experiencing an EBV infection.
However, it is essential to note that MS symptoms typically do not manifest until approximately ten years after patients acquire an EBV infection. Researchers theorized that this delayed onset might be partially attributed to ineffective MS diagnosis protocols, as early symptoms are difficult to detect.
What This Means for MS Patients
Currently, no effective EBV infection treatments or preventatives exist. However, researchers are optimistic that the development of an EBV vaccine or antivirals could pave the way for a multiple sclerosis cure.
In the meantime, patients suffering from MS should continue to work with their primary care providers to mitigate the impact of symptoms and slow the progression of the condition.
For those seeking an alternative treatment option, stem cell therapy has shown some promise for treating neurodegenerative conditions like MS. Stem cell therapy may yield several positive benefits such as a reduction in muscle spasticity, improved balance, increased energy, and reduced muscle pain.
by Stemedix | Mar 21, 2022 | Stem Cell Therapy, Autoimmune, Mesenchymal Stem Cells
For decades, autoimmune diseases such as Lupus, Rheumatoid Arthritis, and chronic obstructive pulmonary disease (COPD) have posed a major challenge to researchers and healthcare providers. While medical interventions have evolved tremendously in the last few decades, these serious conditions remain notoriously difficult to treat. Here we talk about Stem Cell for Autoimmune Diseases, Specifically Mesenchymal stem cells!
Fortunately, mesenchymal stem cells may be a potentially effective treatment option for many patients suffering from various autoimmune conditions. While the efficacy of this intervention varies depending on unique patient factors, individuals who have had little to no success with traditional interventions may find it useful to consider MSC therapy.
What Are MSCs?
Mesenchymal stem cells are a special type of cell that can transform into other types of cells. MSCs can become specialized cells such as those that form muscular tissue, cartilage, and many others. MSCs can be harvested from many different locations, including bone marrow, adipose (fat) tissue, and the Wharton’s Jelly within umbilical cords.
Once harvested, MSCs can be administered to help manage various conditions and their symptoms. MSCs are typically administered through a systemic application into the blood system. However, they can also be directly administered to have a more targeted impact on a specific area depending on the patient’s case.
Can MSCs Be Used to Treat Autoimmune Diseases?
While MSCs are still being studied, research has indicated that MSCs can be an effective intervention for many different autoimmune conditions, including COPD.
Specifically, mesenchymal stem cells have been effective at treating chronic inflammation, which is a common symptom in many autoimmune patients.
However, every case and patient is unique. Therefore, treatment decisions should be made with the guidance of a licensed medical professional. An experienced care provider can thoroughly review your medical history and condition to help you select the best treatment plan for your needs.
Potential Benefits of Stem Cell for Autoimmune Diseases MSCs
Mesenchymal stem cells have the unique potential to reduce inflammation in individuals suffering from an autoimmune disease, such as Lupus or Rheumatoid Arthritis. There is a correlation between a reduction in inflammation and improvements in other disease symptoms. However, the strength of this correlation is still being researched.
With that being said, MSCs may reduce the severity of many common autoimmune symptoms, including pain and fatigue.
Although research is still in progress, mesenchymal stem cell therapy has shown promise for patients looking for an alternative option. With new advancements in medical tools and therapeutic methodologies, patients who suffer from autoimmune disorders may soon have more options for relief than ever before. If you are interested in learning more about Stem Cell for Autoimmune Diseases, contact us today and speak with a care coordinator!
by Stemedix | Mar 14, 2022 | Stem Cell Therapy, Degenerative Disc Disease
Degenerative disc disease is one of the most common and misunderstood causes of lower back pain and neck pain. Instead of referring to a specific ailment, degenerative disc disease is a catch-all term covering many conditions that arise due to general wear and tear on a spinal disc. Here we will talk about Degenerative Disc Disease: Steroids Vs Stem Cell Therapy.
The word “degenerative” implies that the symptoms occur in older people and worsen with age. However, it refers to the disc degenerating over time. While most patients with degenerative disc disease are in their 30s or 40s, it’s not uncommon to present in patients in their 20s.
Symptoms of Degenerative Disc Disease
Patients with degenerative disc disease are generally active and otherwise healthy. Symptoms that many patients experience include:
- Pain that is worse when sitting
- Pain that worsens when bending, lifting, or twisting
- Feeling better when walking or running than standing
- Periods of severe pain that come and go
- Numbness or tingling in extremities
- Weakness in arms or legs
- Hot, shooting pain in the arms or legs
Most patients with degenerative disc disease experience chronic low-level pain with episodes of severe pain.
Treatment Options for Degenerative Disc Disease
Many patients with degenerative disc disease experience relief from natural treatments or lifestyle changes that alleviate pressure and strengthen the muscles around the affected disc. These include:
- Physical therapy
- Occupational therapy
- Weight loss
- Personalized exercises
When these options don’t provide relief, medical interventions may be necessary. Medical practitioners’ standard treatments for degenerative disc disease are surgical intervention or epidural steroid injections. However, the emergence of regenerative medicine, also known as stem cell therapy, adds a new, viable option for degenerative disc disease.
Surgical Intervention
Surgical options for those suffering from degenerative disc disease may alleviate pain but don’t always address the root cause. The least intrusive surgical option is a microdiscectomy, removing the intervertebral disc fragments that cause pain by compressing the spinal nerve root.
Another surgical option to treat degenerative disc disease is spinal fusion surgery. In this procedure, patients find relief through fusing the vertebrae around the injured disc, limiting the movement of the affected disc.
Unfortunately, the fused vertebrae divert the pressure over time to other spine areas, and new problems often arise, such as herniation, stenosis, or spondylosis.
Lastly, some patients opt for a total disc replacement surgery, where an artificial disc replaces the affected disc. Total disc replacement surgery often sees the same outcomes as spinal fusion surgery.
Epidural Steroid Injections
Many patients who want to avoid surgery find pain relief through steroid injections. Steroids provide powerful anti-inflammatory medications to the herniated disc, reducing the sensitivity of nerve endings and triggering the body’s natural healing process.
While steroid injections are an effective tool for treating disc herniation, they are less effective in treating deeper disc issues.
Stem Cell Therapy
New research reveals that adult stem cells may effectively treat back pain caused by degenerative disc disease. Since the spine’s discs have a minimal blood supply, their ability to heal themselves is limited.
However, stem cells’ uniqueness lies in their ability to repair damage. When injected into a damaged disc, they have the potential to regenerate the ligaments, repair soft tissue damage and promote healing. In some cases, stem cell injections restore disc heights to normal levels, and alleviate pain in. Relief and improvements have been reported to be felt within six months of therapy.
Treatments for degenerative disc disease have long fallen short of providing a long-term solution to ongoing pain. However, the emergence of stem cell therapy as a treatment offers new hope for those suffering from chronic back pain. If you are interested in learning more about steroids vs stem cell therapy contact a care coordinator today and schedule a free consultation. If you would like to take a look at some of reviews you can do so here!
by admin | Mar 9, 2022 | Health Awareness, Chelation Therapy
Chelation therapy is an effective treatment for heavy metal poisoning. First used in the 1950s to treat lead poisoning, healthcare providers now use chelation therapy regularly to remove several heavy metals from the body, including lead, mercury, iron, copper, arsenic, aluminum, and calcium.
How Does Chelation Therapy Work?
Chelation therapy removes metals from the bloodstream using ethylenediaminetetraacetic acid (EDTA). A healthcare provider injects EDTA into the bloodstream. ETDA travels throughout the body, collecting metals and forming a compound. The kidneys eliminate the compound through urination.
What Are the Symptoms of Heavy Metal Toxicity?
Environmental metals in the body can cause short and long-term health consequences. Metal toxicity affects the central nervous system, the skeletal and muscular systems, and the immune system. Symptoms of heavy metal toxicity include:
- Forgetfulness
- Chronic fatigue
- Joint or muscle pain
- Autoimmune disease
- Mood changes
Heavy metal toxicity can also cause long-term damage to vital organs if left untreated.
What Are Potential Benefits of Chelation Therapy?
While research into the benefits of chelation therapy is still ongoing, promising studies show that the treatment can potentially reduce inflammation, improve heart health, and reduce infections.
Heart Health
Atherosclerosis, also referred to as the hardening of the arteries results from the buildup of cholesterol and calcium deposits. Injecting EDTA into the bloodstream may collect and remove the calcium in the arteries, loosening blockages and aiding in blood flow.
Antioxidants
Chelation agents, like EDTA, may work similarly to antioxidants in the body, reducing inflammation and removing metals that serve as the foundation of disease development.
Cognitive Health
Research shows that increased copper, iron, and zinc may be associated with various neurodegenerative diseases, including Parkinson’s disease and dementia. Using chelation therapy to remove metals throughout the body can potentially relieve these cognitive disorders.
The potential of chelation therapy for treating various conditions continues to emerge. New studies and research suggest that this alternative treatment may soon become more mainstream.
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