Developing weak and brittle bones from osteoporosis can lead to mild bone stress — like that from bending over — causing a fracture. Most bone fractures from osteoporosis occur in the wrist, hip, or spine. While there is no cure for osteoporosis, there are treatments and medications that can help strengthen and protect your bones. Here we will discuss the benefits of Regenerative Medicine for Osteoporosis.
What Causes Osteoporosis?
Bones are living tissue. Your body constantly breaks down old bone cells and replaces them with new cells. Young bodies form new bone faster than old bone breaks down, increasing bone mass. That process slows in your early 20s, and bone mass typically peaks by the age of 30.
After your bone mass peaks, the formation process slows, and you begin losing bone faster than you create it, causing a loss of bone mass.
Many factors contribute to developing osteoporosis. Your bone mass development is partially inherited, but it’s also affected by hormone levels, diet, exercise, medical conditions, and lifestyle choices.
How Does Regenerative Medicine Work?
Regenerative medicine, also known as stem cell therapy, involves stem cells that are often called the building blocks of all cells. They contain unique healing capabilities, as they’re the only cells in the body that can divide to create two more stem cells or differentiate to form two new specialized cells.
Stem cells lie dormant in tissue like bone marrow or adipose tissue (fat) until they’re needed to restore damaged or dead cells. Stem cell therapy extracts those dormant stem cells, then injects them into damaged areas to foster healing.
How Can Stem Cells Treat Osteoporosis?
From the beginning, researchers sought out mesenchymal stem cells (MSCs) to help manage osteoporosis. They believed that MSCs would increase bone mass by producing new bone cells faster than they age, similar to the process that happens in your youth.
They were pleased to find that MSCs have even more capabilities in treating osteoporosis than expected, as they secrete bioactive molecules and growth factors fostering bone tissue repair and remodeling.
Combining MSCs’ growth factor secretion and differentiation capabilities allows them to repair and restore bone cells efficiently. As a result, stem cell therapy has the potential to help manage the effects of osteoporosis and potentially restore bone strength and mass.
While research continues around specific protocols for using stem cells to manage osteoporosis, early studies show promise for this groundbreaking therapy. To learn more about regenerative Medicine for Osteoporosis contact a care coordinator today at Stemedix!
Once you recover from an initial pain from an injury, dealing with the lengthy recovery time required before you can fully resume your regular activities can become challenging. Regenerative medicine may be able to offer faster, more complete healing to help restore function after an injury and have you back on your feet more quickly.
What Is Regenerative Medicine?
Regenerative medicine is an emerging field of care that focuses on amplifying the body’s natural healing abilities to restore damaged or diseased cells and tissues. Treatments such as stem cell therapy and platelet-rich plasma offer a minimally invasive way to expedite healing after an injury.
Stem Cell Therapy
Stem cells lie dormant in the body until there is a need to replace or repair specialized cells. Stem cells can divide infinitely and have the unique capability to differentiate or separate to create specialized cells, such as brain cells or muscle cells.
For example, if you tear a ligament in your knee, stem cells have the capability to differentiate into the cells necessary to repair your injured ligament. Stem cell therapy introduces a high concentration of those cells into the area, accelerating the healing process.
Platelet-Rich Plasma (PRP)
The platelets in your blood serve as the body’s first responders when you experience a wound. While it’s common knowledge that platelets provide necessary clotting to stop you from losing excessive blood from a small cut, they also contain critical growth factors, proteins, and bioactive lipids that foster repair and recovery.
Platelet-rich plasma (PRP) comes from your blood. After a standard blood draw, the sample goes into a centrifuge, where it is separated into PRP, platelet-poor plasma, and red and white blood cells. A physician then can administer the PRP into the injury site to stimulate the healing process and enhance its outcome.
What Conditions Can Benefit from Regenerative Medicine?
Regenerative medicine can help manage a wide range of painful or slow-healing conditions, including:
Sprains and strains
Tendinitis
Pulled muscles
ACL tears
Fractures
Rotator cuff injuries
Fractures
Meniscus tears
Additionally, many sports medicine physicians offer regenerative medicine treatments to speed up surgery recovery or slow the progression of degenerative conditions.
Regenerative medicine provides an option to explore that may potentially allow you to quickly return to normal activities while amplifying your body’s healing process. For those who struggle to slow down as they recuperate, regenerative medicine offers a beneficial solution for a faster, more comprehensive recovery.
Mesenchymal stem cells (MSCs) are multipotent fibroblast-like cells found throughout the body and have been found to have self-renewing and multilinear therapeutic potential by providing new cells for tissue repair by replacing damaged cells.
Thought to stimulate repair and control the immune response through an expression of growth factors and other cytokines, MSCs are at low risk of rejection and repair tissue damage through immunomodulation, not by their ability to differentiate.
While MSCs can be isolated from a number of tissue sources, including bone marrow, peripheral blood, adipose (fat) tissue, umbilical cord blood, and umbilical cord tissue (Wharton’s jelly). MSCs derived from the human umbilical cords (UCMSCs) have been found to have significant advantages over MSCs isolated from other sources. These advantages include higher proliferation and self-renewal capacity and multilineage differentiation capability.
Unlike many sources of MSCs, the umbilical cord is considered medical waste, making the collection of UCMSCs noninvasive and eliminating ethical concerns associated with the collection of MSCs from other sources. These UCMSCs have been developed as effective “off-the-shelf” cell therapy for a number of conditions, including autoimmune diseases, and as a treatment for a number of emergency medical conditions.
This Phase 1 clinical study, designed and conducted by Chin et al., intended to determine the safety and efficacy of intravenous allogeneic infusion of UCMSCs in healthy volunteers and to determine the effective dose at which an immunomodulatory effect is observed. The findings of this study are intended to serve as a guideline and benchmark for future CVL-100 clinical research.
Analyzing the results of this clinical study, the authors report that there was no observed complication resulting from the infusion and no significant adverse event in either dosage group in the 6 months of follow-up. These findings led Chin et al. to conclude that UCMSCs infusion was safe among healthy subjects, results that were consistent with other UCMSC treatment-based studies.
The authors also reported that UCMSCs infusion posed no significant adverse effects in patients with type 2 diabetes. Despite the relatively small sample group of this study (11 subjects), the authors reported demonstrating an initial transient proinflammatory effect followed by a significant and prolonged anti-inflammatory effect.
In addition, Chin et al. report found that high-dose (HD) CLV-1000 infusion provided a significant increase in both hemoglobin level and MCV level that falls within the normal range. Biomarker assessment results also indicated that the HD group demonstrated a significant steady increase of cytokine IL-1RA from baseline up until 6 months of posttreatment. This finding is especially important as IL-1RA is a naturally occurring antagonist to the proinflammatory cytokine 1L-1.
The authors conclude that this study clearly demonstrates a difference in immunomodulatory effect between the high-dose and low-dose treatment groups, with the HD group demonstrating a significantly greater reduction of proinflammatory cytokine TNF-α and an increased level of specific anti-inflammatory cytokines within 6 months and in relation to those in the low dose group. Considering this, Chin et al. conclude that a CLV-100 dosage of two million MSCs per kilogram of body weight represents the optimal dose level for overcoming inflammatory conditions by displaying the best improvement in all parameters tested, absence of side effects, and SAEs.
The data collected in this study also suggests that this is the first study to report a significant reduction of globulin observed over the course of the study. This is important because globulin serves an important role in immunity. Additionally, increases in serum globulins are associated with several immune-mediated diseases, including rheumatoid arthritis, chronic liver disease, diabetes mellitus, and cancer.
Considering these findings, the authors of this study conclude that high doses of allogeneic MSCs could help exert beneficial effects of repair and healing.
Peptides can be beneficial for your general wellness. They exist naturally within your body, but they can also be administered through regenerative treatments.
What are these compounds, and how can they be used in regenerative medicine?
Peptides Are Strings of Amino Acids
Peptides are made of amino acids, the chemical building blocks for proteins. Your body makes and uses many different peptides for different purposes.
Some peptides generate beneficial tissues and compounds, like collagen or creatine. Others work through medications to combat certain health conditions, such as diabetes.
Peptides can boost your health and well-being in many ways when used in regenerative treatments.
Creatine Peptides for Muscle Growth
Creatine peptides may boost muscle growth and strength over time. These muscle-building peptides can be used in treatments that aim to alleviate musculoskeletal pain.
When your muscle fibers break down and are not repaired properly, you can experience pain, discomfort, and loss of mobility. Peptides can reinforce the structure and strength of your muscles to help you regain comfort and mobility.
Collagen Peptides for Skin and Hair Rejuvenation
Many supplements contain collagen peptides, which are believed to enhance the skin barrier. Collagen is a skin fiber that keeps your skin firm, elastic, and resistant to impact. As you get older, your body produces less collagen, and your skin starts to age.
With collagen peptides, your body can repair and reinforce your skin barrier to give you a more youthful appearance. They can also slow the skin aging process by giving your body the building blocks to make more collagen.
Collagen peptides can also enhance your hair health. If you struggle with hair loss and balding, collagen peptides could make a noticeable difference. Collagen fibers add strength and structure to your hair for enhanced growth.
Peptides for Joint Recovery
Joint health is important for mobility, comfort, and quality of life. Certain peptides may aid in joint recovery and regeneration to ease the painful symptoms of some joint problems.
When you lose cushioning around your joints due to tissue degeneration, you might experience pain and stiffness in these areas. Certain peptides may help rebuild these tissues to make movement and functioning easier and more comfortable.
Combined with stem cell therapy, peptides could reduce inflammation around your joints to give you a better quality of life.
Regenerative Medicine: Peptides for Healing and Relief
Regenerative medicine uses the power of peptides and other compounds to potentially manage symptoms and relieve pain. If you struggle with chronic health problems, this could be a game changer for your daily functioning and comfort levels.
There are endless types of medicinal treatments available to treat your health concerns, but one of the more innovative approaches in regenerative medicine. It focuses on using your body’s own materials to stimulate a healing response in your cells, tissues, muscles, and more.
Types of Regenerative Medicine
There are several types of regenerative medicine, but the two most popular treatments are stem cell therapy and PRP injections.
Stem Cell Therapy
Stem cell therapy is a regenerative medicine treatment that uses natural stem cells to produce an intense healing response within the body. When your body’s own stem cells are injected into certain problem areas, they begin to repair damaged cells, nerves, and other tissues. They can also stimulate the growth of new cells and tissues.
PRP Injections
PRP injections are another type of regenerative medicine treatment. PRP refers to “platelet-rich plasma,” which is the portion of your blood that is high in platelets. During PRP therapy, platelet-rich plasma is harvested from your own blood and injected back into specific areas of the body. This can elicit a healing response and new cell growth.
Uses for Regenerative Medicine
Regenerative medicine can be used to treat a variety of concerns, both aesthetic and medical. The following are some of the most common uses for regenerative medicine treatments:
Alzheimer’s Disease
Alzheimer’s is a progressive neurological disease that impacts memory and cognitive skills. It typically occurs in the late 60s and older but can begin at younger ages. Stem cell therapy may be able to treat the symptoms of Alzheimer’s and slow the progression of the disease by directly targeting nerve pathways and repairing damaged brain tissue.
Autoimmune Diseases
Autoimmune diseases like lupus and rheumatoid arthritis can cause chronic pain and impact the way your immune system functions. Regenerative medicine therapy may be a treatment option for certain autoimmune issues, helping stimulate new cell growth and strengthen the immune system.
Signs of Aging
Wrinkles, fine lines, and facial creasing are some of the most common signs of aging. Regenerative medicine, like PRP therapy, can resolve these age-related changes by stimulating new skin cell growth.
Seeking Regenerative Medicine Treatment
You may be a candidate for regenerative medicine treatment if you struggle with anything from chronic pain to hair loss. Many of these treatments are still being researched, and methods are constantly being improved. Speak to your physician about potential regenerative medicine therapy for your concerns.
Contact Us
If you’re interested in learning more about innovative and advanced medical technologies like regenerative medicine treatment, contactStemedix today to learn more about the treatment options we have to offer!
Regenerative medicine, also known as stem cell therapy, uses the body’s natural healing response to promote tissue regeneration and repair. While the field is still developing, its benefits span many applications, from treating chronic illnesses to restoring function after sports injuries.
The most common treatments in regenerative medicine are stem cell therapy and platelet-rich plasma (PRP). Both methodologies start with the patients’ cells, genuinely capitalizing on self-healing and offering surprising benefits.
Alleviating Chronic Pain
Stem cell and PRP therapy introduce healing cells into damaged areas. Those cells can reduce inflammation, build new tissue, and prevent scar tissue from forming.
Patients might see the most benefits from using these therapies to alleviate pain from soft tissue injuries, including sprained ligaments, torn tendons, and strained muscles. In addition, new research shows promise for the treatment of degenerative conditions, such as osteoarthritis and degenerative disc disease.
Reduce the Use of Long-Term Medications
Traditional medical solutions for injuries or chronic pain include pain relievers or corticosteroid injections. Unfortunately, prolonged or excessive use of some medications harms your overall health.
Additionally, corticosteroid injections can cause more damage to your cartilage, tendons, nerves, and joints, despite temporarily alleviating pain symptoms.
Regenerative medicine treatments aim to heal the underlying cause of pain, not temporarily mask symptoms, reducing patients’ reliance on medications for relief.
Improve Healing Speed
Specific tissues and injuries take longer to heal than others. For example, the body’s healing process slows with age, lengthening the recovery period even for minor injuries. In addition, more severe injuries often take longer to heal.
Generally, slow-healing injuries are those that affect tissues with little blood supply, such as tendons or cartilage. Since platelets and stem cells travel through the blood to promote healing, injuries to these tissues take longer to recover.
Supplying damaged tissue with an extra boost of growth factors through PRP or stem cell therapy can help speed up the healing process.
Low Risk of Side Effects
When possible, regenerative treatment start with the patient’s own healing cells. As the treatment comes from the patient, there is little risk of rejection, infection, scarring, or heavy bleeding.
Overall Resilience and Strengthening
The effects of regenerative medicine can support long-term health and resilience. These treatments can potentially continue to strengthen the treated area even after healing as the tissues become more resilient and robust.
Regenerative medicine offers versatile, minimally invasive options to restore damaged tissue for more comprehensive healing. As science continues to develop these treatments, many patients are already enjoying the benefits of regenerative medicine. To learn more about the benefits of regenerative medicine, contact us today!
This website and its contents are not intended to treat, cure, diagnose, or prevent any disease. Stemedix, Inc. shall not be held liable for the medical claims made by patient testimonials or videos. They are not to be viewed as a guarantee for each individual. The efficacy for some products presented have not been confirmed by the Food and Drug Administration (FDA).
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