Cardiovascular diseases continue to be the leading cause of death globally, accounting for nearly 18 million deaths each year with heart attack and stroke accounting for 80% of deaths. Recently, stem-cell-based therapy has demonstrated the potential to regenerate damaged myocardium and to treat a wide range of cardiovascular diseases (CVDs). Specifically, the ability of mesenchymal…
Recent advances in medical accessibility, technology, and treatment have increased the average human life expectancy, while at the same time, increasing the risk for neurodegenerative diseases and other disorders - including stroke. According to the CDC, nearly 800,000 people in the United States suffer a stroke each year, with 87% of these strokes being ischemic…
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Affecting an estimated 15 million people in the United States alone, COPD is characterized by progressively worsening symptoms, including breathing difficulty, cough, mucus (sputum) production, and wheezing, and is most often the result of prolonged exposure to…
Osteoarthritis (OA) is the most common form of arthritis and is estimated to affect over 500 million people worldwide. A result of the progressive deterioration of the protective cartilage that cushions the ends of the bones, OA most commonly affects the hands, knees, hips, and spine and is characterized by pain, stiffness, and loss of…
Neuropathic pain (NP) is a complex, wide-ranging, and often debilitating condition that contributes to chronic pain. Caused by a number of different factors and contributors, the condition most commonly involves disease, chronic condition, or injury to the nervous system. Defined by the International Association for the Study of Pain (IASP) as pain that occurs as a…
Stem cell therapy is a type of regenerative medicine that involves using stem cells to promote the repair, regeneration, or replacement of damaged or diseased cells, tissues, or organs in the body. Stem cells are undifferentiated cells that have the ability to develop into many different types of cells, such as muscle, bone, or cartilage…
Diabetes is one of the most common conditions in the world, affecting more than 37 million people in the United States alone. Diabetes is a chronic condition that affects your body’s ability to process glucose, resulting in high blood sugar levels. An estimated 96 million people have prediabetes, meaning they could soon be diagnosed with…
Multiple sclerosis (MS) is a chronic and progressive neurological disease that affects the central nervous system (CNS), which includes the brain and spinal cord. MS occurs when the immune system mistakenly attacks the myelin, a fatty material that surrounds and protects nerve fibers, causing inflammation and damage to the myelin and the nerve fibers themselves.…
The National Institute of Health estimates that nearly 250,000 people in the United States are currently living with a spinal cord injury (SCI). Most often a result of an accident, SCIs typically result in the loss of neurons and axonal damage resulting in the loss of function. SCIs can be divided into two distinct phases,…
Arthritis is a common condition, and according to the World Health Organization (WHO), it is estimated that over 300 million people worldwide have some form of arthritis. In the United States, the Centers for Disease Control and Prevention (CDC) estimates that over 54 million adults have doctor-diagnosed arthritis, which represents over 23% of the adult…
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