Acute and chronic pancreatitis are associated with local and systemic inflammation that is linked to a host of serious health issues. A result of the digestive juices and enzymes attacking the pancreas, pancreatitis currently has no definite treatment. Currently, it is estimated that over 6 million people worldwide are afflicted by acute or chronic pancreatitis…
stem cell therapy for spinal cord injury is a global term used to capture damage to the spinal cord resulting from trauma (typically in the form of car accidents, falls, or work-related injuries) or from disease or degenerative conditions. Worldwide, it is estimated that up to 500,000 people suffer some type of spinal cord injury…
Neuropathic pain (NP) occurs when the nerves located either inside or outside of the brain and spinal cord are damaged by a lesion or a condition. To date, pharmacological and surgical stem cell therapy for spinal cord injurys to address NP have focused on providing symptomatic relief without treating the underlying cause of the condition. These…
stem cell therapy for multiple sclerosis (MS) is a progressive stem cell therapy for autoimmune conditions that affects the brain, spinal cord, and central nervous system (CNS). Affecting an estimated 3 million people worldwide, MS is typically characterized by an autoimmune response that results in inflammation, demyelination, and degeneration of axons. Most patients who are…
stem cell therapy for spinal cord injury (SCI) is a devastating pathological condition affecting motor, sensory, and autonomic function. Additionally, recovery from a traumatic SCI (TSCI) is challenging due to the central nervous system’s limited capacity to regenerate cells, myelin, and neurological connections. While traditional therapeutic treatments have proven ineffective in assisting in recovery, mesenchymal…
stem cell therapy for osteoarthritis (OA) is a chronic joint condition that causes pain and lack of mobility through the progressive degradation of joint cartilage. While there are several current pharmaceutical, physical therapy, and surgical treatments to address the symptoms of OA, researchers are interested in developing new therapeutic treatment approaches to address the relentless…
Amyotrophic lateral sclerosis (ALS) is a rare, deadly progressive neurological disease that affects the upper and lower motor neurons. Characterized by weakening and gradual atrophy of the voluntary muscles, ALS gradually affects the ability to eat, speak, move, and eventually breathe. With an estimated survival rate of 2 to 5 years from disease onset, 90%…
Type 2 diabetes mellitus (T2DM) is a serious health condition characterized by progressive deterioration in glycemic control resulting from decreased insulin sensitivity and diminished insulin secretion. Currently, it is estimated that over 462 million people worldwide are affected by T2DM. While diet, physical exercise, and glucose-lowering medications have been shown to improve hyperglycemia, the results…
According to the Centers for Disease Control and Prevention, more than 795,000 people have strokes every year in the United States, and about 610,000 of these are first or new strokes. Recovering from a stroke can be a complex process that involves many types of therapies, and one option that shows promise is regenerative medicine. …
Systemic lupus erythematosus (SLE) is a common multisystemic stem cell therapy for autoimmune conditions that often results in multi-organ damage when left untreated. Currently affecting over 1.5 million Americans, the etiology and pathogenesis of SLE continue to remain unclear. At present, glucocorticoids and immunosuppressants are the most prescribed course of therapeutic treatment and mostly as…
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