Can New Neural Cells Support an Injured Spinal Cord? A spinal cord injury can interrupt the communication pathways that carry movement and sensory signals between the brain and body. Because the spinal cord has a limited ability to repair itself, restoring these damaged connections remains one of regenerative medicine’s biggest challenges. A first-in-human Phase I…
Editing Stem Cells to Change the Course of Disease Sickle cell disease is an inherited blood disorder that causes red blood cells to become rigid and misshapen. These abnormal cells can block blood flow, leading to painful episodes known as vaso-occlusive crises, along with anemia and damage to organs over time. A Phase 3 clinical…
Can Kidney Cells Be Used to Support Kidney Health? Diabetic kidney disease is a serious complication of diabetes that can gradually reduce how well the kidneys filter the blood. Even with today’s medications, some patients continue to lose kidney function over time. A recent Phase II clinical trial explored a regenerative approach called rilparencel, a…
Could PRP Help When Knee Arthritis Becomes Severe? For people living with advanced knee osteoarthritis, everyday activities like walking, climbing stairs, or standing for long periods can become increasingly difficult. As cartilage wears down and inflammation develops, pain and stiffness can make it harder to stay active. A 2026 clinical trial explored whether platelet-rich plasma…
Could PRP Help With More Than Back Pain? Lower back pain can make even simple activities, like sitting at a desk, bending down, or enjoying a walk, uncomfortable. For some people, the problem begins with the spinal discs, which act as cushions between the bones of the spine. When these discs begin to wear down,…
Could Umbilical Cord Blood Help Support Movement? For children with cerebral palsy, everyday movements such as sitting, standing, and walking can require extra effort. Cerebral palsy affects how the brain controls movement and posture, making physical therapy and other supportive treatments an important part of daily life. Researchers are now exploring whether umbilical cord blood…
What If the Benefits of MSCs Aren’t Just About the Cells? Systemic lupus erythematosus (SLE), commonly called lupus, is an autoimmune condition in which the immune system mistakenly attacks healthy tissues. Because lupus can affect different parts of the body, managing inflammation and an overactive immune response is an important part of treatment. A recent…
Could Lost Retinal Cells Be Replaced? Age-related macular degeneration (AMD) is a leading cause of vision loss, affecting the central vision people use for reading, driving, and recognizing faces. In dry AMD, specialized cells in the back of the eye gradually become damaged or lost, contributing to worsening vision over time. A first-in-human clinical trial…
Making More From Umbilical Cord Blood Umbilical cord blood has been used as a source of blood-forming stem cells for decades. These cells can rebuild the blood and immune system after intensive treatment, making cord blood an important transplant option for people with serious blood disorders and cancers. One challenge, however, is that a single…
Looking Beyond Everyday Knee Pain Knee osteoarthritis can turn simple activities like walking, climbing stairs, or getting out of a chair into uncomfortable tasks. While cartilage changes are part of the condition, inflammation inside the joint can also play an important role in pain and stiffness. A recent randomized clinical trial explored whether umbilical cord-derived…
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