Mesenchymal Stem Cells

Regenerative Medicine for Stroke Recovery

According to the Centers for Disease Control and Prevention, more than 795,000 people have strokes every year in the United States, and about 610,000 of these are first or new strokes. Recovering from a stroke can be a complex process that involves many types of therapies, and one option that shows promise is stem cell…

Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles Immunomodulatory Effects in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a common multisystemic autoimmune disease that often results in multi-organ damage when left untreated. Currently affecting over 1.5 million Americans, the etiology and pathogenesis of SLE continue to remain unclear.  At present, glucocorticoids and immunosuppressants are the most prescribed course of therapeutic treatment and mostly as a way to manage…

A Review on the Potential of Mesenchymal Stem Cells and Exosomes for Parkinson’s Disease

Parkinson’s disease (PD) is the second most predominant neurodegenerative disorder worldwide, affecting over 10 million people. Characterized by a slow and progressive loss of control of the neurological system as a result of dopamine depletion, symptoms of PD often include tremors, slowed movement, impaired posture and balance, and gradual loss of automatic movements. While PD…

A Review on Mesenchymal Stem Cell in Intrathecal Applications

Stem cells respond to signals released by damaged or diseased tissue by differentiating in an effort to replace these cells.   As researchers continue to learn more about the various applications of stem cells as they relate to the body’s healing process, they’ve discovered two significant issues relating to the process of stem cell application. The first…

A Review of Regenerative Medicine for Erectile Dysfunction Using Stem Cells

Erectile dysfunction (ED) is a disorder that affects the quality of life and the sexual relations of more than half of the male population aged over 40 years. Currently, it’s estimated that his disorder will affect more than 300 million men in the next five years. According to the Mayo Clinic, male sexual arousal is…

Mesenchymal Stem Cell Transplantation in the Management of Autoimmune Diseases

Recent estimates indicate that one in every 10 people is affected by an autoimmune disease.   Autoimmune diseases occur when the normal function of the immune system mistakenly attacks normal and healthy cells within the body; examples of autoimmune diseases include rheumatoid arthritis, type 1 diabetes, and lupus. Currently, there are over 80 known types of…

Mesenchymal Regenerative Medicine: A New Therapeutic Approach for Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a progressive, inflammatory rheumatoid disease that, over time, can result in chronic spinal arthritis and can cause the vertebrae to fuse together. Affecting an estimated 300,000 people in the U.S., AS causes the spine to become less flexible and can result in a hunched posture. There is no current treatment for…

Mesenchymal Stem Cells and Hyaluronic Acid for Articular Cartilage Defects

Articular cartilage primarily consists of chondrocytes and extracellular matrix and has an essential role in the process of joint movement, including lubrication, shock absorption, and conduction.  However, over time, damage to the articular cartilage caused by acute or repetitive trauma or disease of the joints - including osteoarthritis - often results in pain, lack of…

Mesenchymal Stem Cells for Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that causes inflammation to affect many different body systems including the joints, skin, kidneys, blood cells, brain, heart, and lungs. Affecting over 5 million people worldwide, and associated with a wide range of symptoms, SLE is difficult to diagnose. Currently, there is no treatment to prevent or…

Regenerative Medicine Using Mesenchymal Stem Cells

Biomedical applications of mesenchymal stem cells (MSCs) in the field of regenerative medicine continue to evolve. Coupled with the rapid development of molecular biology and transplantation techniques, MSC applications have become a central focus of research surrounding regenerative medicine.  Since being discovered nearly 50 years ago, the understanding of various techniques for MSC extractions and…

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