Lots of symptoms and signs can warn you that you may be at risk of suffering from heart disease, but did you know erectile dysfunction is one of them? Learn more about the connection between cardiovascular issues and erectile dysfunction — and what treatment options you may have.
Understanding How Erections Form
To understand how erectile dysfunction may be a sign of heart disease, it’s first necessary to know how an erection forms.
Erections don’t just depend on the correct functioning of the genitals. Instead, the process relies on a complex set of interactions between your hormones, brain, blood vessels, and muscles throughout the body.
The moment there’s a mental or physical stimulus, the process begins. When you’re aroused, your brain uses your blood vessels and nerves to send signals to the rest of your body. These signals stimulate blood to flow to the penis, letting the erectile chamber expand.
Testosterone levels also play a role since it functions as a vasodilator, opening up your blood vessels.
If there’s any kind of issue in any of these steps, it can result in erection problems. That also includes if your heart isn’t strong enough to pump blood or if there’s plaque buildup in your blood vessels. If either of those things happens, your erectile chamber won’t expand.
Some of the most common signs of erectile dysfunction include:
Being able to get an erection but not maintain it long enough for intercourse.
Only sometimes being able to get an erection before intercourse.
Requiring a lot of stimulation to get or maintain an erection.
Complete inability to get an erection.
It can be normal to have trouble every once in a while, getting an erection, but if it starts occurring regularly, you should visit your doctor to understand what the problem is.
Heart Disease and Erectile Dysfunction: Shared Risk Factors
Heart disease and erectile dysfunction share common risk factors, which is why, many times, one of these issues can point to another.
Shared risk factors of these conditions include:
Age
Diabetes
High blood pressure
Non-active lifestyle
Smoking
High cholesterol
Obesity
Stress
If you have a family history of heart disease or erectile dysfunction, you are also more likely to develop the problem yourself because there are genetic factors at play.
Is Erectile Dysfunction a Heart Disease Warning Sign?
Erectile dysfunction isn’t always a sign of heart disease, but it often is. This is because of the heart’s function in the process of forming an erection.
If the arteries in the body are affected by atherosclerosis, which is when plaque builds and doesn’t allow as much blood to flow, this can lead to problems with blood flow to the penis. Atherosclerosis also increases your chances of having a heart attack.
Because the arteries in the penis are so narrow, erectile dysfunction can be the first sign of plaque buildup.
Another potential connection between erectile dysfunction and heart disease is endothelial dysfunction. This condition is when the blood vessels constrict instead of dilating, and it’s a type of non-obstructive coronary artery disease. Your arteries narrow even though there’s nothing blocking them.
Treating Erectile Dysfunction
If you struggle with erectile dysfunction, your healthcare provider might suggest a number of treatment options depending on the underlying cause of the problem.
If the problem is related to cardiovascular issues, including atherosclerosis, treatments can include lifestyle changes. This can mean becoming more active by adding cardiovascular exercises like walking, swimming, and jogging to your life. Always speak with your doctor before beginning any kind of exercise routine.
Quitting smoking is another step you can take, as is adjusting your diet. You should limit your intake of saturated fats so that you can start lowering your cholesterol levels.
You’ll want to avoid alcohol as well. Alcohol interferes with the messengers in the brain that tell the penis to fill with blood while also reducing the production of testosterone levels. Alcohol is also bad for your heart since it causes high blood pressure, putting more stress on the organ.
Some oral medications that increase blood flow to the penis aren’t a good choice if you also have some types of heart disease, so it’s important to ensure that your doctor identifies what’s causing the erectile dysfunction before prescribing medications.
An option that shows promising results is regenerative medicine. Regenerative medicine options like stem cell therapy provide the chance to treat the underlying cause of erectile dysfunction.
Stem cell therapy relies on stem cells, which have the ability to transform into many other kinds of cells, encouraging the growth of healthier blood vessels so that the penis can receive better blood flow.
One of the most important benefits stem cell therapies offers is that it doesn’t require an invasive procedure.
Another regenerative medicine treatment option is platelet-rich plasma (PRP) therapy. PRP therapy uses a sample of your blood that contains concentrated platelet levels and is full of growth factors.
A PRP injection stimulates blood flow and the growth of new and healthier blood vessels.
Getting Help for Erectile Dysfunction
Erectile dysfunction can impact your whole life, affecting your self-esteem and even warning you that there may be other health issues to consider. Turning to your healthcare provider is the best thing you can do to understand what the underlying cause of the problem is and whether it points to issues like cardiovascular disease.
For many men, dealing with erectile dysfunction, with or without heart disease issues, means making lifestyle changes and considering treatment options like regenerative medicine.
Because choices like PRP therapy and stem cell therapy provide the chance to get to the root problem without putting you at risk of side effects, as medication does, it could be the right choice for men who are struggling with both erectile dysfunction and heart problems.
Parkinson’s disease causes nervous system complications. If you know someone who has struggled with this disease, you know how debilitating it can be. Parkinson’s affects mood, memory, cognition, and movement.
Fortunately, science is always advancing, and experts are learning more about Parkinson’s disease. Here are seven ways to help prevent Parkinson’s disease that are backed by scientific research.
1. Do Cardio Regularly
Cardiovascular exercise is linked to many other health benefits, but one of the most notable is reduced risk of Parkinson’s disease. Aerobic exercise, even in mild forms like walking or jogging, boosts your brain health. This improves and protects your memory, concentration, mood, and cognitive abilities as you age.
Cardio has an anti-inflammatory effect on your entire body. This is significant because researchers believe that Parkinson’s is the result of excess inflammation, among other factors. By getting a moderate to high amount of aerobic exercise each week, you can help protect yourself from developing this debilitating disease.
2. Relieve Stress in Healthy Ways
Psychological stress can be just as harmful as physical stress. Between the demands of work, family life, social circles, and hobbies, many modern Americans are more stressed than ever before.
It’s essential to reduce stress to stay healthy throughout your lifetime. Chronic high stress levels can contribute to whole-body inflammation, which is a serious risk factor for Parkinson’s disease.
Stress also reduces the volume of brain matter in areas that control memory, cognition, and movement, which are all negatively affected by Parkinson’s disease. By regularly combating stress, you can protect your brain and reduce your chances of developing this problematic condition.
Some healthy forms of stress relief include:
Exercise
Journaling
Meditation
Yoga
Self-care days
Getting at least eight hours of sleep at night
Spending time outdoors
Engaging in hobbies
These activities help you stay well-adjusted and free of stress, which weighs down your mental and physical health over time. Consider making changes in your life that cut out large sources of stress whenever possible.
3. Fill Your Plate with Veggies
Most people know that vegetables are extremely healthy. If you struggle to get your daily servings of veggies in, this information might make you reconsider your habits.
Vegetables naturally contain antioxidants, which are anti-inflammatory compounds that protect against aging and tissue damage. Filling your plate with vegetables increases your intake of antioxidants, vitamins, and minerals. All of these micronutrients contribute to better brain health and anti-aging.
When it comes to Parkinson’s prevention, this is one of the most effective steps you can take. If taste is an issue, consider adding more flavors to your meals to offset the taste of vegetables. You can also add seasoning and heart-healthy oils to make vegetables taste better.
4. Avoid Pesticides and Other Harsh Chemicals
Modern agriculture has changed a lot as humanity has progressed past the hunter-gatherer days. This means that crop growers are using more chemical pesticides than ever before. The long-term effects of these chemicals on human health are overwhelmingly negative.
Some studies have linked higher rates of Parkinson’s disease with high exposure to pesticides in farmers. The harsh chemicals used in large-scale agriculture are designed to keep bugs away from crops, but they can harm your brain health in the process.
To avoid this problem, shop organic and local whenever possible. Be mindful that many organic products can still contain certain pesticides. It’s best to shop at your local farmer’s markets and small grocery stores rather than chains.
These steps will help you access high-quality produce without exposing yourself to harsh, damaging chemicals.
5. Increase Your Vitamin D Intake
Vitamin D is incredibly important for immunity, mood, bone health, and brain health. Research has shown strong connections between Parkinson’s disease and low vitamin D levels. Now more than ever, getting enough vitamin D in your diet is essential.
You get some vitamin D from sunlight. The sun’s rays boost the amount of vitamin D in your bloodstream through chemical changes.
However, too much sun exposure is linked to skin cancer and other serious health problems. You should always wear sunscreen while spending extended amounts of time outdoors, and this can reduce the amount of vitamin D you get from the sun.
You should aim to get most of your vitamin D from your diet and supplements. Healthy sources of animal fat naturally contain lots of vitamin D. Opt for meats and dairy products that have “grass-fed” or “free-range” on the labels. These animals and their products are healthier and richer in vitamin D than factory-farmed animals.
If you struggle to get enough vitamin D in your diet, work with your doctor to find an appropriate supplement. Always consult a medical professional before starting a new medication or supplement.
6. Get Plenty of Sleep
Sleep is the most restorative and reparative process your body undergoes. Without enough sleep, your brain health is sure to suffer. Your memory, cognition, mood, and physical performance all rely on an adequate amount of sleep.
Parkinson’s disease is a neurodegenerative disorder, so it makes sense that chronic lack of sleep can raise your chances of developing it.
Healthy adults should get seven to nine hours of sleep every night. Your sleep needs may be slightly different from the recommended range. It’s important to pay attention to how you feel when you wake up.
If you wake up groggy, tired, and sluggish even after eight hours of sleep, chances are you need more. On the other hand, some people can thrive on seven to eight hours of sleep with no problems.
Sleep will protect your brain health and fight inflammation that can lead to Parkinson’s disease. Make getting plenty of shut-eye a strong priority in your life — your brain will thank you later.
7. Drink Coffee or Green Tea
Caffeine seems to have a protective effect against developing Parkinson’s disease. It’s important to get high-quality sources of caffeine. Otherwise, you may notice sleep disturbances and cardiovascular side effects. Avoid sugary, caffeinated beverages like energy drinks and soda.
Green tea and coffee both have antioxidants, which reduce inflammation and promote better brain health. You don’t have to give up your daily fix to fight Parkinson’s — in fact, it may help!
Know the Facts About Parkinson’s Disease
Stay updated on the latest information about Parkinson’s disease to reduce your risk of developing it. If you or a loved one are already struggling with Parkinson’s, therapeutic treatments like stem cell therapy may help. Ultimately, knowledge is power when it comes to fighting neurodegenerative diseases.
With more than 17,000 people in the US sustaining a spinal cord injury (SCI) each year and an estimated combined cost to healthcare and the workforce exceeding $40 billion, the condition has significant personal and socioeconomic implications. In addition, SCIs have limited pharmacological treatment options to support the regeneration of nerve damage.
Considering the limited treatment options for this condition, the field of regenerative medicine, and specifically the use of stem cells, has recently drawn interest as a potential therapeutic treatment option for paralysis resulting from SCIs.
In this report, Bydon et al. summarize findings of the ongoing multidisciplinary phase 1 clinical trial exploring the safety and efficacy of intrathecal autologous adipose tissue-derived (AD) mesenchymal stem cells (MSCs) in patients with blunt, traumatic SCI.
Specifically, as part of this report, the authors describe the outcome of the first patient with C3-4 SCI treated with AD-MSCs. At the time of SCI, neurologic examination revealed complete loss of motor and sensory function below the level of injury; an injury diagnosed as an American Spinal Injury Association (ASIA) grade A SCI.
After undergoing initial treatment, including C2-6 posterior cervical decompression and fusion, improvement in motor and sensory function was demonstrable. However, neurological gains plateaued 6 months after sustaining injury.
Upon enrollment into the CELLTOP clinical trial 9 months after injury, the patient’s neurologic status was found to be ASIA grade C and imaging revealed bilateral myelomalacia at the C3 level and at the C2-6 decompression and fusion. Additionally, an open biopsy of adipose tissue found in the abdominal wall was performed 8 weeks prior to receiving an initial intrathecal injection.
After receiving an intrathecal injection of 100 million autologous AD-MSCs 11 months after injury, the patient was observed for clinical signs of efficacy at 3, 6, 12, and 18 months following injection.
Bydon et al. observed progressive improvement in upper extremity motor scores and considerable improvement in lower extremity scores at 18 months following injection. The patient also demonstrated consistent improvement in ASIA sensory score, including improvements in pinprick and light touch scores at follow-up after 18 months. The authors reported patient improvements in Capabilities of Upper Extremity score, quality of life (as measured by Global Health Score), and in physical and occupational therapy measures. Other than a moderate headache on day 2, no other safety issues or adverse events were reported.
While further clinical trial is required, the authors conclude that intrathecal AD-MSC administration may be a relatively noninvasive and safe therapeutic option for patients with SCI to improve their neurologic status after reaching a ceiling effect in terms of spontaneous recovery.
Chronic obstructive pulmonary disease affects 16 million adults in the United States, according to the National Heart, Lung, and Blood Institute. COPD refers to two main conditions — chronic bronchitis and emphysema. If you’ve received a COPD diagnosis, it can be tough to know what to expect from the disease as it progresses. For many people, one of the leading questions is whether COPD can be reversed. Learn more about this disease and what kind of treatments offer promising results.
Symptoms of Chronic Obstructive Pulmonary Disease
COPD occurs because of damage to the airways or other parts of the lungs, blocking airflow and making it more difficult to breathe. Both chronic bronchitis and emphysema can lead to the development of COPD.
Chronic bronchitis affects your bronchial tubes, which carry air to and from your lungs. Bronchitis irritates these tubes, leading to the production of mucus that narrows the tube’s opening, making it much harder to breathe.
Usually, hair-like structures called cilia move mucus out of your airways, but the irritation from bronchitis damages the cilia.
Emphysema is a condition that affects the air sacs at the end of the bronchial tubes. These air sacs assist in the transfer of oxygen into your blood and carbon dioxide out. Emphysema destroys the walls of these sacs, making it tough to get a breath.
COPD can cause symptoms that include:
Shortness of breath
Chest heaviness or tightness
Fatigue
Ongoing cough
Whistling or wheezing when you breathe
Cough with mucus
Not everyone who has COPD experiences all of these symptoms.
Causes of COPD
One of the biggest risk factors of COPD is smoking. The majority of people who have COPD smoke or has a history of smoking. If you have a family history of COPD, you are more likely to develop it if you smoke. Smoke irritates the airways, causing inflammation while also damaging the cilia that moves mucus.
If you’ve suffered long-term exposure to other lung irritants, you could also be at risk. Irritants can be chemical fumes, dust, air pollution, smoke from home cooking, and heating fuel. Secondhand smoke can also be a factor.
Your age is also a consideration if you have other risk factors. Most people who have COPD are at least 40.
Infections like tuberculosis and HIV also put you at risk. If you have asthma, you also could experience COPD.
One of the potential genetic causes of COPD is a condition called alpha-1 antitrypsin (AAT) deficiency. If you have this condition, long-term exposure to fumes or smoking can result in lung damage, leading to COPD. AAT deficiency makes it easier to develop the disease earlier in life.
Treatment of COPD: Managing Symptoms
Treating COPD means finding ways of decreasing symptoms. The first thing you have to do is to quit smoking if you’re still engaged in this habit. Continuing to smoke as you deal with COPD will only make the condition worse.
Bronchodilators and steroids are options that can help with symptoms. If you have mild COPD, your doctor may prescribe short-acting bronchodilators that you use only when you experience symptoms. These bronchodilators relax the muscles around the airways.
If you have a more severe case of COPD, you may need to take bronchodilators every day. In some instances, your doctor may prescribe them along with steroids.
Can COPD Be Reversed? For some people, pulmonary rehabilitation is helpful. This option includes exercise training and breathing techniques to help you better manage the symptoms.
Oxygen therapy is another option. You receive supplemental oxygen from tubes that rest in your nose, a face mask, or a tube that goes into your windpipe.
Surgery is generally only done in people with severe COPD that doesn’t respond to other treatment options. There are a few different types of surgeries. Getting a lung transplant is another option, though it is even rarer than surgery.
Slowing the Progression of COPD: Promising Options
Although it’s not yet possible to reverse the conditions, it can be possible to slow down the progression of COPD. The first step is to get an early diagnosis and intervention. If you suspect you have COPD, it’s important to ask your doctor for a spirometry test.
If you have a family history of the condition or have smoked for a long time, it can help to get a test even if you don’t have symptoms.
It can also be helpful to learn both diaphragmatic breathing and pursed-lip breathing. Diaphragmatic breathing stimulates relaxation and increases oxygen saturation while also reducing the amount of air trapped in your lungs. Pursed-lip breathing, on the other hand, offers quick relief for someone experiencing shortness of breath and wheezing.
You will also need to avoid environmental triggers. These triggers can include air pollutants, extreme temperature changes, smoke, and strenuous activities.
Additionally, stem cell therapy offers the chance to slow down the progression of COPD. It uses stem cells to stimulate your body to start healing itself. It could speed up your lungs’ ability to heal themselves.
Stem cell therapy can also be helpful in preventing inflammation by assisting you in producing anti-inflammatory molecules.
One of the best things about stem cell therapy and other regenerative medicine options is that it’s minimally invasive and doesn’t require a long recovery process. You also don’t have to worry about side effects or rejections.
Living With COPD: Choosing the Best Treatment Strategies
Once your lungs suffer the kind of damage COPD causes, reversing the condition is usually not an option. However, this doesn’t mean you can’t improve your symptoms and even dramatically slow down the disease’s progression.
Stem cell therapy is an option that offers the chance to help your body heal itself, even if not entirely. A combination of treatments can be the most effective way of dealing with COPD, so make sure to speak with a specialist on your treatment options.
Spinal cord injury is one of the most complicated and serious pathological impairments affecting the central nervous system. Since the human body is unable to regenerate and repair the spinal cord after injury, there is a high likelihood of suffering permanent damage and disability.
Often compounding the issue of SCI, secondary events occurring after the initial injury to the spinal cord significantly reduce cell migration and axonal regrowth and limit repair and regeneration.
Recently, transplantation of mesenchymal stem cells (MSCs) has been shown to promote the repair of injured spinal cord tissues in animal models. However, as Qu and Zhang highlight in this review, there remain many unanswered questions that are essential for improving the effects of this MSC therapy. As such, the authors focus this review on recent information about the behavior and function of MSCs in SCI, the function of biomaterials to direct the behavior of MSCs, and the attempt to emphasize combinational strategies such as tissue engineering for functional improvements of SCI.
There are studies showing that the migratory and homing capacities of MSCs are closely related to their engraftment and regeneration ability. Considering this, the authors highlight the importance of having MSCs migrate and integrate into host spinal cord tissue. Since MSC homing toward injured tissue is not an efficient process, and to ensure a more effective stem cell therapy outcome, it is important that these transplanted cells be introduced in a way that increases the migratory potential of healthy MSCs to the site of injured tissue.
Additionally, while transplanted cells have been identified adjacent to neurons after SCI, the surviving number of grafted and differentiated neurons was too small to be considered to contribute to functional recovery after SCI. However, data suggests that the ability of MSCs to secrete soluble factors or vesicles rather than engrafting and transdifferentiating might serve an important role in SCI repair.
The authors also point to studies that indicate MSC implantation could promote a therapeutic effect and functional recovery in experimental SCI animal models. The authors believe that this is a result of MSCs ability to differentiate into specialized neuronal and glial cell lineages after transplantation. While MSC transplantation has not yet been proven to be an effective and reliable therapy for SCI, additional studies need to be done before the therapy is utilized in clinical applications.
MSCs respond to the local environment in multiple ways and represent the most promising exosomes for neuropathic applications. Qu and Zhang conclude this review by calling for more intensive studies examining the potential benefits of combining MSCs with nerve tissue-engineered scaffolds to direct cell behaviors after SCI, including growth, migration, and differentiation.
In the United States, about 30 million men have some form of erectile dysfunction, according to research conducted by the National Institute of Diabetes and Digestive and Kidney Diseases. Erectile dysfunction can occur in men of any age, though it’s most common in those who are older. Despite this, it’s not a normal part of aging. There are many causes of erectile dysfunction, from emotional to physical. However, most people are unaware of a few risk factors that could affect your chances of developing this condition.
Understanding Erectile Dysfunction
Erectile dysfunction is a condition in which you are not able to get or maintain an erection firm enough for sexual intercourse. It can be a long-term or short-term problem.
There are a few types of erectile dysfunction. One type is vascular erectile dysfunction, which results from issues with the blood vessels that send blood to the penis or the valves that hold blood. This is the most common form of erectile dysfunction.
Neurogenic erectile dysfunction occurs as a result of nerve problems that stop signals from traveling from your brain to your penis. It can occur after trauma, radiation therapy, or conditions like spinal stenosis and multiple sclerosis.
Hormonal erectile dysfunction occurs when you experience testosterone deficiencies, while psychogenic erectile dysfunction involves psychological causes.
Surprising Risk Factors for Erectile Dysfunction
Most men are aware that blood pressure issues, antidepressants, and even drinking alcohol can cause erectile dysfunction. Still, there are some surprising factors that can make your chances of dealing with this problem more likely.
1. Sleep Apnea
Sleep apnea is a condition in which your breathing stops and restarts many times as you sleep. This irregularity leads to poor rest. Scientists have noticed that men who have sleep apnea have a higher risk of developing erectile dysfunction.
The reason is not entirely clear, but it could be because the lack of sleep leads to dips in testosterone levels. Sleep apnea also restricts oxygen. Testosterone and oxygen are both crucial for maintaining healthy erections.
Sleep apnea also leads to fatigue and potentially higher stress levels, all of which impact sexual function. Scientists have found that treating obstructive sleep apnea can also help erectile dysfunction symptoms.
2. High Cholesterol
Having high blood cholesterol levels could also put you at a higher risk of developing erectile dysfunction. Perhaps the most common cause is the narrowing of blood vessels, also called atherosclerosis. High cholesterol levels can make this more likely to occur.
Cholesterol is a fat-like substance in the blood that your cell membranes need and that helps produce certain hormones, bile acids, and vitamin D. At high levels, however, cholesterol builds up in artery walls and causes plaque, which narrows them.
When that occurs, your penis doesn’t receive the amount of blood it needs to get and maintain an erection.
3. Cycling
Although maintaining an active lifestyle tends to help with erectile dysfunction, cycling could be causing more harm than good.
Hard bicycle seats often press on the perineum, which is the area between the scrotum and the anus, causing a compression of blood vessels. The compression makes it more difficult for the penis to get the needed blood flow.
Scientists recommend using a softer seat or taking shorter rides to prevent the problem. Make sure to speak with your doctor about this if you suspect cycling could be causing erectile dysfunction issues.
4. Canned Foods
Perhaps one of the most surprising risk factors of erectile dysfunction is the frequent eating of canned foods. Cans that hold food often contain the chemical bisphenol-A, also called BPA. BPA can affect your hormones, stimulating the production of female sex hormones and suppressing male sex hormones.
5. Certain Medications
Lots of medications have the potential to affect sexual function, especially in men. This is because they can interfere with hormone pathways.
One of these types of medications is selective serotonin reuptake inhibitors (SSRIs). These medications are antidepressants that function by increasing the levels of serotonin in the body, elevating your mood. The problem is that serotonin decreases sex drive.
Blood pressure medications may also affect sexual function. Diuretics or ACE inhibitors decrease the blood flow that reaches the penis, making an erection more difficult to achieve.
Other medications that could affect sexual function are those that treat Parkinson’s disease, antihistamines, and even non-steroidal anti-inflammatory disease. It is always a good idea to speak with your doctor about the side effects of any medications you take and to work with them to find alternatives.
6. Leading a Sedentary Lifestyle
Another factor that can put you at risk of developing erectile dysfunction is leading a sedentary lifestyle. Being sedentary can cause decreased blood flow. Not leading an active life also makes it harder for your heart to function at its best.
Even moderate exercise stimulates your body to produce nitric oxide, which is a short-lasting chemical that keeps your arteries open, including the ones that allow blood to flow into your penis.
A sedentary lifestyle is associated with higher levels of fat in the body. The more fat you have, the more estrogen your body is likely to produce, which means your testosterone levels dip. It can also lead to a higher risk of developing diabetes, which impacts insulin resistance and makes the development of erectile dysfunction more likely.
Treating Erectile Dysfunction
Struggling with erectile dysfunction can affect your self-esteem, moods, and relationships. If you are dealing with this issue, it’s essential to reach out to your doctor for help.
One option that offers the chance to get relief from erectile dysfunction is regenerative medicine. Regenerative medicine treatments like stem cell therapy focus on doing more than just treating the symptoms of the condition: they can help to treat the underlying problem that led to erectile dysfunction issues in the first place.
If you are dealing with erectile dysfunction, consider asking your doctor about regenerative medicine. With these minimally invasive treatments, you could allow your body to start healing itself.
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