Mesenchymal Stem Cells

February 22, 2024

Phase 1 Clinical Trial Investigating the Use of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Traumatic Spinal Cord Injury

Adipose, Mesenchymal Stem Cells, Spinal Cord Injury, Stem Cell Research

With more than 17,000 people in the US sustaining a spinal cord injury (SCI) each year and an estimated combined cost to healthcare and the workforce exceeding $40 billion, the condition has significant personal and socioeconomic implications. In addition, SCIs have limited pharmacological treatment options to support the regeneration of nerve damage. Considering the limited…

February 15, 2024

The Anti-Inflammatory Effects of Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes on Osteoarthritis Chondrocytes

Exosomes, Extracellular Vesicles, Mesenchymal Stem Cells, Osteoarthritis, Stem Cell Research

Osteoarthritis (OA) is the most common form of arthritis and is estimated to affect nearly 365 million people worldwide. Characterized as an inflammatory disease, OA slowly progresses over time and results in the gradual loss of the protective cartilage found on the ends of the bones. While the specific cause of OA has yet to…

February 8, 2024

Functions of Mesenchymal Stem Cells in Spinal Cord Injuries

Mesenchymal Stem Cells, Spinal Cord Injury, Stem Cell Research

Spinal cord injury is one of the most complicated and serious pathological impairments affecting the central nervous system. Since the human body is unable to regenerate and repair the spinal cord after injury, there is a high likelihood of suffering permanent damage and disability. Often compounding the issue of SCI, secondary events occurring after the…

February 8, 2024

Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis

Mesenchymal Stem Cells, Osteoarthritis, Stem Cell Research

Osteoarthritis (OA) is the most common form of arthritis and occurs as a result of the protective cartilage, found on the ends of the bones, degenerates over time. While OA can occur in any joint, it is most commonly found to occur in the hands, hips, spine, and knee. An estimated 365 million people worldwide…

February 1, 2024

Treating Psoriasis Using Regenerative Medicine

Mesenchymal Stem Cells, Psoriasis, Stem Cell Research

Characterized by scaly white or erythematous plaques, psoriasis is a chronic autoimmune dermatological disease most often appearing on the scalp, genitalia, lumbosacral area, and extensor surfaces of the limbs. Affecting an estimated 125 million people worldwide, the condition most commonly is observed in those between the ages of 15 and 25 years of age. The…

January 31, 2024

Exploring the Potential of Regenerative Medicine in Addressing the Challenges of Pancreatitis

Mesenchymal Stem Cells, Stem Cell Research

Acute and chronic pancreatitis are associated with local and systemic inflammation that is linked to a host of serious health issues. A result of the digestive juices and enzymes attacking the pancreas, pancreatitis currently has no definite treatment. Currently, it is estimated that over 6 million people worldwide are afflicted by acute or chronic pancreatitis…

January 25, 2024

Using Mesenchymal Regenerative Medicine for Traumatic Spinal Cord Injury

Mesenchymal Stem Cells, Spinal Cord Injury, Stem Cell Research

Spinal cord injury is a global term used to capture damage to the spinal cord resulting from trauma (typically in the form of car accidents, falls, or work-related injuries) or from disease or degenerative conditions. Worldwide, it is estimated that up to 500,000 people suffer some type of spinal cord injury (SCI), with most resulting…

January 18, 2024

A Systematic Review of Mesenchymal Regenerative Medicine in Multiple Sclerosis

Mesenchymal Stem Cells, Multiple Sclerosis, Stem Cell Research

Multiple sclerosis (MS) is a progressive autoimmune disease that affects the brain, spinal cord, and central nervous system (CNS). Affecting an estimated 3 million people worldwide, MS is typically characterized by an autoimmune response that results in inflammation, demyelination, and degeneration of axons. Most patients who are diagnosed with MS demonstrate a disease progression characterized…

January 4, 2024

Harnessing Exosomes as Cutting-Edge Drug Delivery Systems for Revolutionary Osteoarthritis Therapy

Exosomes, Mesenchymal Stem Cells, Osteoarthritis, Stem Cell Research

Osteoarthritis (OA) is a chronic joint condition that causes pain and lack of mobility through the progressive degradation of joint cartilage. While there are several current pharmaceutical, physical therapy, and surgical treatments to address the symptoms of OA, researchers are interested in developing new therapeutic treatment approaches to address the relentless progression of the condition.…

December 28, 2023

Assessing The Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stem Cells in Chinese Adults with Type 2 Diabetes

Diabetes, Mesenchymal Stem Cells, Stem Cell Research

Type 2 diabetes mellitus (T2DM) is a serious health condition characterized by progressive deterioration in glycemic control resulting from decreased insulin sensitivity and diminished insulin secretion. Currently, it is estimated that over 462 million people worldwide are affected by T2DM. While diet, physical exercise, and glucose-lowering medications have been shown to improve hyperglycemia, the results…

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