Mesenchymal Stem Cells

July 8, 2022

Human mesenchymal stem cells (MSCs) for treatment towards immune- and inflammation-mediated diseases: review of current clinical trials.

Mesenchymal Stem Cells, Stem Cell Research

Human Mesenchymal Stem Cells (hMSCs) are the non-hematopoietic, multipotent stem cells with the capacity to differentiate into mesodermal lineages such as osteocytes, adipocytes, and chondrocytes as well ectodermal (neurocytes) and endodermal lineages (hepatocytes). Until recently, when the immunomodulation properties of MSCs were proven to be clinically relevant, the use of these stem cells was met…

June 24, 2022

Effects of Mesenchymal Stem Cell-Derived Paracrine Signals and Their Delivery Strategies

Exosomes, Mesenchymal Stem Cells, Stem Cell Research

Mesenchymal stem cells (MSCs) have been widely studied and increasingly recognized as a potential therapeutic with the ability to initiate and support tissue regeneration and remodeling. While over 1100 clinical trials have been conducted to assess the therapeutic benefits of MSCs, there continues to be widespread variation surrounding the potential treatment outcomes associated with these…

May 20, 2022

Regenerative Medicine for Multiple Sclerosis

Mesenchymal Stem Cells

Every year, regenerative medicine gains massive traction due to its incredible regenerative and auto-repair properties. More specifically, patients who deal with chronic, incurable conditions such as multiple sclerosis (MS) are closely following any news about this cutting-edge technology. What is a stem cell? A stem cell is a special biological entity that has unlimited differentiation…

May 13, 2022

Bone Marrow-Derived MSCs to Reduce Neural Damage and Prevent Multiple System Atrophy

Mesenchymal Stem Cells, Stem Cell Research

Multiple system atrophy (MSA) is a rare, degenerative adult-onset neurological disorder that affects your body's involuntary functions, including blood pressure, breathing, bladder function, and motor control. MSA also demonstrates several symptoms similar to those accompanying Parkinson’s disease, including slow movement, stiff muscles, and loss of balance[1]. Considering the rapid and fatal progression of MSA, there…

May 6, 2022

Mesenchymal Stem Cells in Multiple Sclerosis: Recent Evidence from Preclinical to Clinical Studies

Mesenchymal Stem Cells, Multiple Sclerosis, Stem Cell Research

Multiple sclerosis (MS) is a chronic inflammatory disease that attacks myelin, the protective sheath that covers nerves and causes progressive and serious communication issues between the brain, central nervous system, and the rest of the body[1]. Currently, it's estimated that over 2.3 million people worldwide, and over one million people in the US have a…

April 11, 2022

Mesenchymal Regenerative Medicine for Parkinson’s Disease

Mesenchymal Stem Cells, Parkinson’s Disease

Regenerative medicine, also known as regenerative medicine, is emerging as a viable treatment for Parkinson’s disease as clinical trials move through the FDA approval process. Patients in clinical trials see positive results from mesenchymal regenerative medicine for Parkinson's Disease. What Is Parkinson’s Disease? Parkinson’s disease is a progressive, neurodegenerative condition. It occurs when dopamine-producing brain…

April 1, 2022

Heterogeneity of Mesenchymal Stem Cells in Cartilage Regeneration

Adipose, Mesenchymal Stem Cells, Musculoskeletal, Wharton’s Jelly

Articular cartilage, found on the surface of most musculoskeletal joints, distributes and transfers forces between bones and joints, provides a smooth surface for joint mobility, and plays an important role in human mobility. However, articular cartilage is also easily susceptible to damage, but difficult to repair itself on its own (primarily due to the fact…

March 25, 2022

Can Regenerative Medicine Help Manage Neurodegenerative Conditions?

Mesenchymal Stem Cells, Neurodegenerative Diseases, Stem Cell Research

Neurodegenerative conditions such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) occur when neuron populations begin to diminish. There is currently no cure for these types of diseases, though clinical trials to explore various treatment options are ongoing. In particular, regenerative medicine, also known as regenerative medicine, is being heavily researched…

March 21, 2022

Stem Cells For Autoimmune Diseases: MSCs

Autoimmune, Mesenchymal Stem Cells

For decades, autoimmune diseases such as Lupus, Rheumatoid Arthritis, and chronic obstructive pulmonary disease (COPD) have posed a major challenge to researchers and healthcare providers. While medical interventions have evolved tremendously in the last few decades, these serious conditions remain notoriously difficult to treat. Here we talk about Stem Cell for Autoimmune Diseases, Specifically Mesenchymal…

January 21, 2022

Safety and Clinical Outcomes In Chronic Ischemic Stroke Patients After Implantation of Mesenchymal Stem Cells

Mesenchymal Stem Cells, Stem Cell Research, Stroke

According to the CDC, stroke continues to be a major cause of serious disability for adults. It is also estimated that nearly 800,000 people in the United States have a stroke each year[1]. While 80% of those experiencing a stroke survive for at least one year following the event, more than 70% will continue to…

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