Lupus

Understanding Lupus

Medical Review: Dr. Gerald Mastaw, MD – Board-Certified PhysicianLast Updated: October 2025 What Is Lupus? Lupus is a chronic autoimmune disease that can affect nearly any organ in the body.When the immune system, which normally protects against infection, starts attacking healthy tissues, widespread inflammation and tissue damage can occur. The most common form is Systemic…

Stem Cell Therapy for Systemic Lupus Erythematosus: A New Frontier in Treatment

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can damage many different parts of the body, including the kidneys, lungs, brain, and blood system. Because it can attack so many organs, it often leads to serious illness and even death.  For many years, doctors have used medications like corticosteroids, cyclophosphamide (CTX), and mycophenolate…

Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles Immunomodulatory Effects in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a common multisystemic autoimmune disease that often results in multi-organ damage when left untreated. Currently affecting over 1.5 million Americans, the etiology and pathogenesis of SLE continue to remain unclear.  At present, glucocorticoids and immunosuppressants are the most prescribed course of therapeutic treatment and mostly as a way to manage…

Mesenchymal Stem Cells for Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that causes inflammation to affect many different body systems including the joints, skin, kidneys, blood cells, brain, heart, and lungs. Affecting over 5 million people worldwide, and associated with a wide range of symptoms, SLE is difficult to diagnose. Currently, there is no treatment to prevent or…

Regenerative Medicine for Lupus

Lupus can be unpredictable, with symptoms that physicians frequently mistake for other illnesses. Since the condition causes the immune system to attack its organs and tissues, it can affect any area in the body, including the skin, kidneys, blood cells, brain, heart, joints, and lungs. While some patients are more likely to develop lupus, the…

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