Articular cartilage is the smooth, white cartilage that covers the ends of the bone in diarthrodial joints. Essential for fluid and pain-free movement, articular cartilage protects the bones by reducing friction and absorbing shock. However, articular cartilage is also subject to damage and injury as a result of normal wear and tear or as a…
stem cell therapy for osteoarthritis is the most common form of arthritis, affecting more than 900 million people around the world. Developing when the cartilage that protects your bones wears down, osteoarthritis (OA) most commonly affects the joints of the hand, hips, spine, and knees[1]. While current treatment for OA and related joint damage is…
When it comes to their potential for biomedical applications, mesenchymal stem cells (MSCs) continue to garner support and attention from the global scientific community. Isolated from a variety of sources, including bone marrow, adipose tissue, and umbilical cord tissue, MSCs demonstrate multipotent differentiation in vitro. In other words, they are tissues that are able to…
Characterized by chronic inflammation that obstructs normal airflow from the lungs, chronic obstructive pulmonary disease (COPD) affects an estimated 65 million people and remains the third leading cause of death worldwide. Caused by prolonged exposure to gasses or other harmful particulates, and especially cigarette smoke, COPD is typically characterized by breathing difficulty, cough, mucus (sputum)…
The immunosuppressive ability of mesenchymal stem cells (MSCs) coupled with their potential to serve important therapeutic roles in a wide range of immune disorders have resulted in a significant increase in the number of clinical studies examining the role of cellular therapy in a wide range of applications. Of particular interest is MSCs’ ability to…
In a recent study, researchers discovered a breakthrough against MS, regenerative medicine might be able to help individuals who have stem cell therapy for multiple sclerosis (MS). The study was conducted by Italian researchers and included a group of 210 MS patients suffering from aggressive cases of the neurodegenerative condition. The study spanned over two…
Neurodegenerative diseases affect over 50 million Americans each year and occur as a result of nerve cells in the brain, peripheral nervous system, and the central nervous system slowly and progressively losing function before eventually dying[1]. Although there are over 600 known neurological disorders, the most common neurodegenerative diseases continue to be Alzheimer’s disease (AD),…
Bone marrow is a vital biological resource used to treat people with diseases such as leukemia and lymphoma. In addition, it has been utilized for regenerative medicine, as bone marrow contains a large concentration of these valuable specialty cells. Once harvested, these stem cells can help treat conditions such as autoimmune conditions, orthopedic injuries, and…
Since their discovery in 1960, mesenchymal stem cells (MSCs) have been found to migrate to assist and support the repair of injured tissue. In addition, and more importantly, MSCs have demonstrated therapeutic effects resulting from their ability to modulate various cells found in both the innate and adaptive immune systems. To date, over 900 clinical…
Mesenchymal stem cells are a specific type of stem cell. MSCs have been the subject of many medical studies and extensive research. MSCs are essentially the raw materials that the body uses to generate new tissues. These versatile cells can differentiate or transform into many different forms of cells, including the following: Like many other…
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