Neurodegenerative diseases affect over 50 million Americans each year and occur as a result of nerve cells in the brain, peripheral nervous system, and the central nervous system slowly and progressively losing function before eventually dying[1]. Although there are over 600 known neurological disorders, the most common neurodegenerative diseases continue to be Alzheimer’s disease (AD),…
Bone marrow is a vital biological resource used to treat people with diseases such as leukemia and lymphoma. In addition, it has been utilized for stem cell therapy, as bone marrow contains a large concentration of these valuable specialty cells. Once harvested, these stem cells can help treat conditions such as autoimmune conditions, orthopedic injuries,…
Since their discovery in 1960, mesenchymal stem cells (MSCs) have been found to migrate to assist and support the repair of injured tissue. In addition, and more importantly, MSCs have demonstrated therapeutic effects resulting from their ability to modulate various cells found in both the innate and adaptive immune systems. To date, over 900 clinical…
Mesenchymal stem cells are a specific type of stem cell. MSCs have been the subject of many medical studies and extensive research. MSCs are essentially the raw materials that the body uses to generate new tissues. These versatile cells can differentiate or transform into many different forms of cells, including the following: Like many other…
Over the last decade, the field of stem cell therapy has grown in research and awareness. This growth is thanks to mesenchymal stem cells (MSCs,) the type of cells most commonly explored for their powerful reparative properties. Medical professionals can harvest and concentrate these MSCs from multiple sources, making them more accessible. As a result, stem…
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder that currently affects nearly 6 million people worldwide and is currently the second most common neurological condition, behind only Alzheimer’s. Although the exact cause of PD remains unclear, the condition is characterized by the gradual loss of nerve cells in the brain responsible for producing the neurotransmitter…
With nearly 30 million people in the US affected by osteoarthritis (OA), the condition continues to be among the leading causes of chronic pain and disability. Considering that advances in medical technology have increased overall life expectancy, the number of people living longer and dealing with the effects of OA is expected to increase for…
Human mesenchymal stem cells (hMSCs) are multipotent adult stem cells found in tissue throughout the body, including in the umbilical cord, bone marrow, and adipose tissue. Capable of self-renewing and differentiating into multiple tissues including bone, cartilage, muscle, fat cells, and connective tissue[1], MSCs appear to have a wide range of potential for use as…
It is estimated that over 126 million Americans, or nearly one in two adults, are affected with some form of musculoskeletal disorder, condition, or injury - a number comparable to the percentage of the population currently living with a chronic lung or heart condition[1]. While there are a number of treatment modalities proven to be…
Typically understood to support hematopoiesis and to produce the cells of the mesodermal lineage, mesenchymal stem cells (MSCs) found in bone marrow, fat, and other tissues of the body, have recently been found to contain additional properties that include immunomodulator and neurotrophic effects. Considering earlier studies that have demonstrated favorable effects of MSC treatments in…
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