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7 of the Best Salad Greens for Your Health

7 of the Best Salad Greens for Your Health

You probably already know that leafy greens are considered the holy grail of nutrition. While they’re low in calories, they’re also rich in the key vitamins and minerals needed to help our body function its best. Yet, a lesser-known aspect of these powerful veggies is that not all are created equal, and in fact, some are far more nutritious than others. Browse through some of the most popular salad greens, ranked from least nutritional to healthiest, below.

#7 Butter Lettuce

While swapping out wraps or bread for butter lettuce is a healthy way to enjoy your favorite sandwich without the carbs, butter lettuce has only small amounts of iron and calcium. It is, however, a good source of vitamin A, which still makes it a strong contender in the realm of salad greens.

#6 Green/Red Leaf Lettuce

Often found in packaged mixed greens, red and green leaf lettuce is well-liked for its mild taste, making it the perfect base for salads with flavorful ingredients. It can also deliver a significant dose of vitamins A and K. Since it’s low in fiber, consider pairing it with some fibrous veggies, including cauliflower, celery, and green peppers.

#5 Romaine

Perhaps the most popular lettuce of all, romaine has a fresh flavor and a rewarding crunch. Although it’s versatile enough to accommodate virtually any toppings, it isn’t quite as nutritional as some of the other types on this list. It does, however, have a high concentration of folic acid, which supports fetal health.

#4 Watercress

Often overlooked here in the U.S., watercress is a popular salad green in Europe. It’s has a higher nutritional value than romaine and leaf lettuce, and delivers nearly the entire daily recommended intake for vitamins A and K. Surprisingly, it’s also a great source of vitamin C.

#3 Swiss Chard

Also, a less popular veggie, swiss chard has similar properties to watercress with lots of vitamins A, C, and K. Yet, it also has iron and calcium, a critical nutrient for supporting bone health. This green from the beet family can be enjoyed raw, but it has less bitterness when cooked. If you don’t find it appealing on its own, consider incorporating it into a soup, omelet, or stir fry.

#2 Spinach

It should come as no surprise that spinach falls so high on the list. Although it has a mild flavor, it provides a wealth of nutrients, including vitamins C and K, as well as fiber and iron. It also has lots of folic acid. While fresh fruit and nuts come together to form a delicious spinach salad, it can also be blended into smoothies without altering the overall taste.

#1 Kale

Often hailed as a “super food,” kale is certainly deserving of its spot as the healthiest salad green. In addition to fulfilling your daily requirements for vitamins A, C, and K, the veggie is a rich source of phytonutrients. These compounds found in plants have powerful benefits, including cancer prevention, heart health, and immune system support.

As you can see, it’s a good idea to switch up your go-to salad every now and then to reap the greatest benefits that greens have to offer.  Whether you’re a longtime kale connoisseur or you’re just starting to broaden your horizons for salad greens, there are many ways a variety of leafy vegetables can help you achieve and maintain your best version of health.

Mesenchymal Stem Cells Exert Therapeutic Effects in Duchenne Muscular Dystrophy

Mesenchymal Stem Cells Exert Therapeutic Effects in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy is a degenerative condition that is hereditary caused by mutations to a gene called dystrophin. The condition affects both skeletal and cardiac muscles, impairing physical mobility and leading to weakened heart and respiratory functioning. Current treatments for Duchenne muscular dystrophy aim to control the symptoms of the condition and enhance the quality of life, but there is no known cure.

Given the need for effective therapies in Duchenne muscular dystrophy and the success of stem cells in treating other degenerative conditions, research has begun to focus on how cell therapies may be able to help Duchenne muscular dystrophy patients. Mesenchymal stem cells have been considered as an approach to this form of therapy.

Much of the research to date has emphasized autologous sources of stem cells that come from the patient themselves – such as from bone marrow or adipose tissues. However, a recent study, published in Biomaterials, investigated the impact of allogeneic mesenchymal stem cells – which comes from someone other than the patient – on Duchenne muscular dystrophy. Specifically, the researchers looked at the therapeutic effects of placenta-derived mesenchymal stem cells.

The scientists found that using placenta-derived mesenchymal stem cells may be able to reduce the amount of scarring and thickening of the connective tissue of the cardiac muscles and diaphragm in Duchenne muscular dystrophy while also minimizing inflammation. These promising findings demonstrate the potential to use stem cells to reverse the pathology of Duchenne muscular dystrophy and not just to address the symptoms. Future research will help to determine if regenerative therapy could have a meaningful impact on the course of this condition.

 

Reference: Bier et al. 2018. Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy. Biomaterials, 174, 67-78.

Here’s What Everyone Should Know About the Keto Diet

Here’s What Everyone Should Know About the Keto Diet

At one point or another, you’ve probably come across something about the “keto diet,” whether it’s a friend who’s lost weight on it or an article on the newsstand. Indeed, it appears that following ketogenic (keto for short) eating principles is the latest dieting fad which has taken the masses by storm. While it does have the potential to spur significant weight loss, however, it also carries certain risks. Here’s what you need to know before going keto.

What Is the Keto Diet?

At the most basic level, keto is a low-carb, high-fat approach to eating. It bears similarities to the Atkins diet and similar low-carb eating plans. Essentially, it requires dieters to drastically limit their intake of carbohydrates (which are found in everything from breads, pasta, and cereal products to fruit) and to replace them with fat. For those who follow the plan strictly, it means breaking down nutrition as follows:

  • 75% fat
  • 20% protein
  • 5% carbohydrates

The average American diet consists of 50-65% of carbohydrates, so the keto diet requires a major dietary overhaul for most people. By making these changes, you’ll send your body into a different metabolic state known as ketosis.

What is Ketosis?

Ketosis is the process by which the body uses stored fat for energy. This occurs when there isn’t enough glucose to provide energy. As stored fat is burned, a buildup of acids known as ketones develop, which can supply the brain with energy. To determine whether they’ve reached ketosis, many individuals who pursue the diet use urine strips or blood pricks. Eventually, however, most people become able to recognize the feeling of being in ketosis.

Keto Meal Planning

Most variations of the keto diet require a strict, principled approach to eating in which high-fat foods like oils, butter, avocado, cheese, coconut, and nuts are used to satisfy the appetite. Non-starchy vegetables such as broccoli, asparagus, zucchini, peppers, and cucumbers, as well as leafy greens, are also permitted. Meats, eggs, and fish can be consumed regularly as well.

The list of restricted foods spans far and wide, however. Most fruits are not permitted, nor are grains of any type, heavily processed foods, alcohol, and milk, among many other foods and drinks.

Keto Diet Benefits

Weight loss is one of the main drivers that attracts people to the keto diet. More than 20 studies have supported low-carb eating approaches, indicating that reducing carbohydrate intake can help people lose weight. This is likely due to the fact that cutting carbs also requires you to nix simple, refined carbohydrates, which are typically caloric yet have little nutritional value.

It’s also suspected that the keto diet may help to control or prevent certain diseases, including epilepsy, metabolic syndrome, type 2 diabetes, obesity, dementia, Parkinson’s disease, polycystic ovarian syndrome, and certain types of cancer.

Despite its potential benefits, however, further research is still limited, especially in terms of long-term results. There are also certain risks all participants should consider before embarking on this diet.

Keto Diet Risks

One of the most notorious impacts of the diet is the “keto flu.” As the body adapts to this new eating approach, it experiences flu-like symptoms, including headaches and fatigue. Water is also lost early on, which can lead to dehydration – a potentially serious condition. It’s therefore critical to drink plenty of water, especially at first.

The diet is also difficult to stick with. Thus, while you may see results at first, it’s important to ask whether reducing carb intake so drastically is a practical long-term eating style you can maintain.

Additionally, a high-fat diet could lead you to take in too many saturated or trans fats, found in foods like red meat, cheese, butter, and poultry skin. These can cause “bad” cholesterol to spike and put you at risk for developing heart disease. Moreover, eliminating entire food groups can lead to unfavorable byproducts like kidney stones and constipation.

Ultimately, while the keto diet may be right for certain populations, it’s a good idea to have a talk with your doctor before you make the switch. By staying hydrated, limiting saturated and trans fats, and eating a healthy variety of keto-friendly foods, you may be able to find success with this approach.

Stem Cells Show Promise for Helping Alzheimer’s Disease with Neurodegenerative Disease via Multiple Mechanisms

Stem Cells Show Promise for Helping Alzheimer’s Disease with Neurodegenerative Disease via Multiple Mechanisms

Alzheimer’s disease is the most common form of dementia, and though its prevalence is growing, there are currently no medical interventions that are able to reverse or slow the disease. Most current therapies address the symptoms of Alzheimer’s disease rather than the underlying cause of the disease.

Stem cells appear to offer a promising opportunity for treating Alzheimer’s disease and other neurodegenerative disorders, and a recent review published in Current Alzheimer Research has covered research into the ways stem cells can be applied to these disorders. Specifically, the authors of the review discuss the stem cell sources that may offer the potential to treat neurodegenerative diseases and the mechanisms by which these stem cells may confer benefits to this set of patients.

According to data collected so far, stem cells may be both safe and effective in treating neurodegenerative disorders like Alzheimer’s disease, but the mechanism by which they produce benefits for those with these disorders is not entirely clear. There are some data that show that the replacement of degenerated tissue with new proliferative stem cells accounts for stem cell benefits in models of neurodegenerative disorders, while other data show that stem cells can lead to advantageous enhancements in the expression of synaptic proteins.

Evidence from other studies, however, suggest that stem cells help with neurodegenerative disease through the release of neurotrophic factors that lead to paracrine benefits. Additional studies point to modulation of the immune system as the way that stem cells may help those with neurodegenerative disorders.

Future research will help to elucidate the specific mechanisms by which stem cells can provide effective therapy for people with neurodegenerative disorders. It may be the case that a variety of stem cell types used in multiple ways can be helpful for neurodegenerative disease therapy, and research will help to delineate the different ways stem cells can be used and inform the therapies that are developed.

 

Reference: Bali, P, et al. (2017). Potential for stem cells therapy in Alzheimer’s disease: Do neurotrophic factors play a critical role? Current Alzheimer Research, 14(2), 208-220.

Hyperbaric Oxygen Therapy for Alzheimer’s Disease

Hyperbaric Oxygen Therapy for Alzheimer’s Disease

Alzheimer’s disease causes patients to have difficulty recalling memories and performing tasks. Alzheimer’s disease is progressive, which means it gets worse over time. Once Alzheimer’s disease begins, patients either stay the same or get worse. Most people notice symptoms getting worse over a period of 10 years. However, some people with Alzheimer’s disease will get worse very rapidly, over the course of a few years.

Because Alzheimer’s disease is discussed frequently in popular media, many people know that part of the disease process is the accumulation of abnormal proteins in the brain, namely beta-amyloid plaques and tau neurofibrillary tangles. One less well-known effect of Alzheimer’s disease is that it interferes with blood flow in the brain. This decreased blood flow is so common, in fact, that doctors can detect low brain activity using positron emission tomography (PET), which can help make the diagnosis of Alzheimer’s disease.

Between 2002 and 2012, researchers tested 244 treatments for Alzheimer’s disease, and only one medication was approved by the FDA. After all this time, there is still no cure for Alzheimer’s disease. In fact, the drugs used to treat Alzheimer’s disease are mostly ineffective. At best, they slow the progression of the disease for several months to a few years.

This lack of success has prompted several research groups to focus on other treatments for Alzheimer’s disease. One experimental treatment for Alzheimer’s disease is hyperbaric oxygen therapy. In hyperbaric oxygen therapy, patients rest in a specialized chamber while they experience oxygen at a slightly higher pressure than they would in the outside world.

Researchers wanted to determine whether hyperbaric oxygen therapy could improve the symptoms of Alzheimer’s disease, but also whether they could see those brain changes using PET. To do this, Drs. Harch and Fogarty enrolled a woman with rapidly deteriorating Alzheimer’s disease in their clinical study. She was exhibiting the characteristic signs of Alzheimer’s disease and reduced brain activity and blood flow in her brain. They treated her with a series of hyperbaric oxygen therapy treatments (1.15 atmospheres, 40 minutes, 5 days per week over 66 days).

After 21 treatments, the woman had increased energy, her mood was better, she was better able to perform activities of daily living, and she was actually performing crossword puzzles. After 40 hyperbaric oxygen treatments, she had better memory and concentration, she was sleeping better, her appetite had improved, she was able to hold conversations and able to use a computer.

Interestingly, when the researchers performed follow-up PET study after hyperbaric oxygen therapy, blood flow and brain activity improved as much as 38% compared to the PET study before treatment.

Additional clinical studies with larger groups of Alzheimer’s disease patients are needed to determine how effective hyperbaric oxygen therapy is, what pressure to use, and how many treatments are needed, etc. Nonetheless, the impressive changes reported in this case study are promising, and should spark additional clinical research.

Contact a Stemedix Care Coordinator for more information on Regenerative Medince Therapy combined with Hyperbaric Oxygen Therapy (HBOT) for Alzheimer’s Disease.

Reference: Harch et al. (2019). Hyperbaric oxygen therapy for Alzheimer’s dementia with positron emission tomography imaging: a case report. Medical Gas Research. 2019 Jan 9;8(4):181-184.

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