by admin | Aug 15, 2024 | Mesenchymal Stem Cells, Stem Cell Research, Stem Cell Therapy
Liver cirrhosis (LC) is a severe global health problem, contributing to an estimated two million deaths annually. LC results from chronic liver diseases such as hepatitis B and C, alcohol consumption, non-alcoholic fatty liver disease, and autoimmune liver disease. When these diseases progress unchecked, they lead to liver cirrhosis, characterized by inflammation and fibrosis. Most patients with LC die from complications due to a lack of effective treatments and poor patient compliance. While liver transplantation is effective, it is costly and comes with risks like immune rejection and recurrent infections. This has led to an urgent need for alternative treatments for LC.
Mesenchymal stem cells (MSCs) offer a promising alternative due to their ability to renew themselves and differentiate into various cell types. MSCs have gained attention for their potential to treat tissue-damaging diseases due to their low immunogenicity and ability to home to injury sites. Animal studies have shown MSCs to be safe and effective in treating LC, and clinical trials indicate improvements in liver function with no significant adverse effects.
Lu et al.’s study aims to systematically evaluate the efficacy and safety of MSCs for treating liver cirrhosis through a meta-analysis of clinical trials.
As part of this study, the authors analyzed data from PubMed/Medline, Web of Science, EMBASE, and Cochrane Library up through May 2023. Researchers used the PICOS principle for literature screening and assessed the risk of bias. Data from each study’s outcome indicators, such as liver function and adverse events, were then extracted and analyzed using Review Manager 5.4.
Eleven clinical trials met the criteria for this analysis. The pooled data showed significant improvements in primary and secondary liver function indicators. Patients who received MSC infusions had higher albumin (ALB) levels at 2 weeks, 1 month, 3 months, and 6 months, and lower MELD scores at 1 month, 2 months, and 6 months compared to the control group. Hepatic arterial injections were particularly effective in improving these scores. Importantly, none of the studies reported severe adverse effects, indicating the safety of MSC therapy.
Key Findings and Recommendations
Considering the findings of this study, the authors provide a number of key findings and recommendations, including:
- Duration of MSC Therapy: The study found that prolonging MSC treatment enhances its effectiveness in end-stage liver disease, improving symptoms such as appetite loss, mental depression, and jaundice.
- Types of MSCs: MSCs can be derived from various tissues, and their effectiveness may vary. Most studies evaluated used bone marrow-derived MSCs (BM-MSCs), which have shown superior therapeutic effects compared to umbilical cord-derived MSCs (UC-MSCs). However, more research is needed to determine the best type of MSC for treating LC.
- Routes of Administration: Different transplantation methods can impact the efficacy of MSC therapy. The hepatic artery route was found to be the most effective, likely due to better MSC homing to the liver. However, this method has clinical limitations such as high surgical risk. Intravenous administration, while safer, was less effective. The authors call for further research to optimize the administration route.
- Secondary Indicators: While primary indicators like MELD score and ALB levels showed significant improvements, secondary indicators such as ALT, AST, TBIL, and INR did not show significant differences between the MSC and control groups. The authors believe this could be due to variability in disease cause, patient population, and follow-up duration.
- Complications and Prognosis: MSC therapy also showed potential in reducing LC complications, such as portal hypertension and ascites, and decreasing mortality and hepatocellular carcinoma (HCC) incidence. However, more clinical trials are needed to confirm these findings and assess the long-term prognosis of MSC therapy in LC.
Lu et al. conclude that mesenchymal stem cell therapy is a safe and effective treatment for liver cirrhosis, significantly improving liver function without severe adverse effects. However, to fully realize the potential of MSC therapy, a standardized treatment protocol is needed. This includes optimizing the timing, dosage, frequency, and administration route of MSC infusions.
Additionally, MSC-derived exosomes show promise as an alternative treatment strategy. The authors call for further research, including multicenter, large-scale, long-term RCTs, to address these questions and improve the therapeutic outcomes for LC patients.
Source: Zhao, Y., Liu, Y., Zhang, W., Li, H., & Wang, L. “Efficacy and safety of mesenchymal stem cells in the treatment of liver cirrhosis: A systematic review and meta-analysis.” Stem Cell Research & Therapy, 2023. https://stemcellres.biomedcentral.com/articles/10.1186/s13287-023-03518-x.
by admin | Aug 3, 2024 | ALS, Mesenchymal Stem Cells, Stem Cell Research, Stem Cell Therapy
Amyotrophic Lateral Sclerosis (ALS) is a degenerative disease that affects motor neurons in the brain and spinal cord, leading to muscle paralysis and death, typically within 3-5 years of onset. Despite two FDA-approved therapies, Riluzole, and Edravarone, which offer limited benefits, there remains no cure for ALS.
Considering this, researchers have turned to Mesenchymal Stem Cells (MSCs), which have shown promise in animal models and preliminary human trials for neurodegenerative diseases, including ALS.
Understanding ALS and MSC Therapy
ALS is characterized by the rapid degeneration of motor neurons, leading to muscle paralysis. The exact cause of ALS is complex and not fully understood. About 10% of cases are familial, while 90% are sporadic. Existing treatments only modestly slow disease progression and extend survival by a few months.
Stem cells, particularly MSCs, have shown potential in neuroprotection and immunomodulation. MSCs can be derived from various sources, including bone marrow, adipose tissue, embryonic tissue, cord blood, reprogrammed mature cells, and perinatal tissue. They support hematopoiesis and produce mesodermal cells. MSCs have demonstrated immunomodulatory and neurotrophic effects in animal models and early human trials.
As part of this study, Petrou et al. aimed to evaluate the safety and efficacy of repeated spinal injections of autologous MSCs in ALS patients. This open-label clinical trial included patients aged 20-70, with definite ALS diagnoses and ALS Functional Rating Scale Revised (ALSFRS-R) scores above 20. The patients received 1-4 intrathecal MSC injections at intervals of 3-6 months, with safety and tolerability as primary endpoints, and efficacy as secondary endpoints.
This trial found no serious adverse events, demonstrating the safety of repeated MSC injections. As evidence, the authors point out that, 15 out of 19 patients showed a reduction in the progression rate of their ALSFRS-R scores by more than 25% between the first and second injections, with an average improvement of 107.1%. Similar improvements were observed between subsequent injections. Thirteen patients experienced a 25% improvement in their progression rate over the entire treatment period, with an average improvement of 47.4%. Seven patients showed clinical improvement after the first transplantation, and five remained improved after the second cycle. These benefits were correlated with the intervals between the injections, suggesting that regular MSC administrations might be crucial for sustained efficacy.
Previous Studies on MSCs in ALS
Several small, open-label clinical trials have suggested that MSC treatment can be beneficial for neurological diseases, including ALS. In a phase I/II trial by the same research group, ALS patients received intrathecal and intravenous MSC injections, which were safe and showed a trend toward disease stabilization over six months. Another phase I/II and IIa trial with Brainstorm® used modified MSCs producing neurotrophic factors (MSC-NTF), showing at least a 25% improvement in disease progression, particularly in the intrathecally treated group.
Additional trials, including a randomized, placebo-controlled phase II study, demonstrated mixed results. While some trials noted improvements in a subgroup of rapid progressors, others did not show significant differences between MSC-treated and placebo groups overall. These studies highlight the need for repeated injections to maintain the benefits of MSC therapy.
Implications From the Current Study
According to Petrou et al., repeated intrathecal injections of MSCs over a longer follow-up period appears to induce significant, but short-term, clinical improvements and slow disease progression in a majority of patients. This study also reaffirmed the safety profile of MSC, with only mild and transient adverse events observed.
The study highlights the potential of MSC therapy in providing neuroprotection and slowing ALS progression. The immunomodulatory effects of MSCs, possibly reducing inflammation in the central nervous system, may also contribute to their therapeutic benefits. However, the small sample size and open-label design are limitations, necessitating larger, controlled trials to confirm these findings.
Future Directions
Petrou et al. concluded that repeated intrathecal injections of autologous MSCs are safe for ALS patients and suggest potential medium-term clinical benefits. However, larger studies are needed to confirm these findings. The consistent observation of safety and indications of efficacy across multiple cycles of treatment is encouraging, indicating that MSC therapy could slow the progression of ALS and improve patients’ quality of life.
The study’s promising results support the continued exploration of MSC therapy for ALS. The authors call for future trials to focus on optimizing the timing and frequency of MSC injections to maximize clinical benefits. Larger, controlled studies are essential to validate these findings and potentially establish MSC therapy as a viable treatment option for ALS. By addressing the unmet needs in neuroprotection and immunomodulation, MSC therapy holds the potential of improving the quality of life and survival for ALS patients.
Source: Panayiota Petrou, Ibrahim Kassis, Nour Eddine Yaghmour, Ariel Ginzberg, Dimitrios Karussis. A phase II clinical trial with repeated intrathecal injections of autologous mesenchymal stem cells in patients with amyotrophic lateral sclerosis. Front. Biosci. (Landmark Ed) 2021, 26(10), 693–706. https://doi.org/10.52586/4980
by Stemedix | Jun 10, 2024 | Back Pain, Chronic Pain, Health Awareness, Pain Management, Regenerative Medicine, Stem Cell Research, Stem Cell Therapy
“Back pain” is a general term that can mean many different things. From nerve pain to strained back muscles, there are various reasons your back might hurt. Dealing with chronic back pain is mentally and physically exhausting, and you deserve relief. The first step in properly managing your chronic back pain is to know what’s behind it. Use this guide to shed some light on the potential root cause of back pain, and available treatments for your comfort.
Why Does Your Back Hurt?
If you’ve experienced severe back pain before, your first question is probably, “Why?” It might feel like you’re willing to do anything to stop the pain.
Unfortunately, there isn’t one universal cause for severe back pain. If you’re struggling with it, it’s time to examine what might be causing it.
Some of the circumstances that can cause chronic back pain include:
- Neurodegenerative disease (like MS or ALS)
- Car accidents
- Sports injuries
- Musculoskeletal problems
- Spinal alignment issues
- Spinal cord infections and diseases
- Orthopedic (bone) problems
- Strained back muscles
- Poor posture
- Neuropathic pain
These are just a few of the debilitating problems you may be dealing with. A qualified healthcare professional can guide you to the proper diagnosis.
Muscular Back Pain
Your back is full of muscles that help you sit, stand, and move around. When one of these muscles’ experiences overuse, stress, or strain, you’ll feel it in major ways.
Movement Injuries
If you twist, sleep, or lift something in the wrong manner, you could end up with a strained back muscle. This will feel different than regular soreness after a back workout.
Sports injuries can affect your back muscles. Especially in contact sports and other intense activities, your back faces many risks each time you play. The more conditioned and flexible you are, the less likely you are to get an overuse or muscle strain injury.
Stress
Psychological stress can also lead to muscular back pain. When you’re stressed, your body tenses up in ways you may not even notice. The muscles in your back may become stiff, strained, or generally uncomfortable as a result.
Lack of Sleep
You also tend to lose sleep when you’re undergoing lots of mental stress. Your body uses sleep as the primary time to repair your muscles and make them stronger. If you aren’t getting enough rest at night or you work the third shift, your back muscles are more prone to pain and injury.
Neurological Back Problems
Your nervous system sends messages to all parts of your body using electrical impulses. The central hub for all of the nerves that extend outward from your body is your spinal cord. Neurological diseases and spinal cord injuries can impair your back in surprising ways.
Neuropathic Pain
Neuropathy develops when nerves throughout your body become damaged in some way. This is a common symptom of neurodegenerative diseases like MS. When your peripheral nerves are damaged, they can’t communicate with your brain properly, leading to strange sensations and pain.
Neuropathic back pain may feel like numbness, tingling, burning, “pins and needles,” or sharp excruciating pains. If you suffer from a neurological health condition, there’s a solid chance your back pain is related.
Car Accidents and Spine Injuries
Automobile accidents exert a lot of force and impact on your body all at once. When you get into an accident, even if it’s minor, your back and neck muscles can experience whiplash. In extreme cases, car accidents can also cause spinal injuries.
Spinal cord injuries are very serious. Your spinal cord protects your nerves and secures their pathway to your brain. Chronic back pain, numbness, and loss of limb function could indicate an underlying spinal injury.
Herniated Discs and Pinched Nerves
If one of the cartilage discs between your vertebrae becomes dislodged, it can press on the nerves surrounding it. A herniated disc can spell trouble for your mobility, limb functions, and comfort for years.
Vertebral problems can also pinch the nerves in your back, which results in the same thing — long-lasting sharp back pain. Discomfort from a pinched nerve will likely feel sudden, sharp, and breathtaking.
Lifestyle Factors and Back Pain
Certain aspects of your lifestyle may be causing your chronic back pain and soreness. These factors aren’t considered diseases themselves, but they can lead to chronic health problems that become long-term conditions.
The following are risk factors for chronic back pain:
- Obesity
- Poor posture
- Sedentary lifestyle
- Overtraining
- Poor nutrition
- Labor-intensive jobs
- Improper lifting techniques
Whenever possible, you should avoid these risks. Steps like wearing a posture corrector and lifting heavy objects with your leg muscles can help prevent chronic back problems.
Solving Your Pain: Back Treatment Options
You don’t have to live in unbearable pain forever. You have options when it comes to severe back pain treatment. Every person has a different threshold for pain, and you may prefer less invasive, more natural treatments than someone else.
Medication
Pain medication will block your brain from receiving pain signals in your back. Medication is a valid option for people struggling to function due to chronic back problems. However, most medications don’t treat the root cause of your back pain. It’s a good idea to consider other treatments along with medication.
Surgery
Back surgery is intense, invasive, and risky, but for some people, it’s the best and only option. Severe spinal cord injuries and disc herniations may require immediate surgery to correct the problem. After surgery, you’ll likely be instructed to perform back exercises to improve your mobility.
Regenerative Medicine
Regenerative medicine, also known as stem cell therapy, for back pain may offer an innovative and cutting-edge option. By utilizing human-derived stem cells to repair and renew damaged tissues throughout your body, these “blank” cells can form into almost any type of specialized cell, making them a potential effective modality to help manage and heal chronic back pain.
Evaluating Your Options
It may take a few different interventions before you experience back pain relief. What’s important is that you don’t give up. With the proper treatment, you can experience mild to intense relief and continue on with your life. Medicine is always improving, and you have more options than ever before.
by Stemedix | Jun 3, 2024 | Age Management, Hair Regrowth, Health Awareness, PRP, Regenerative Medicine, Stem Cell Research, Stem Cell Therapy
Your hair can be part of your identity. For some people, their hair is a symbol of their spiritual beliefs. Whether you’re focused on beauty and aesthetics or a deeper meaning behind your hair, hair loss can be devastating.
For some people, regenerative medicine is an innovative, research-based solution to hair loss. Learn more about how regenerative hair loss treatments may restore your healthy locks.
How Hair Loss Is Related to Your Well-Being
Losing hair is often a symptom of an underlying health problem. While some people experience hair loss due to genetics or lifestyle choices, others may face lurking medical issues. Here are some of the ways your hair growth (or lack thereof) is related to your physical and mental wellness.
Self-Esteem and Confidence
You may feel embarrassed, ashamed, or self-conscious if you start to lose your hair. Both men and women struggle with remaining confident after significant hair loss. Your mental well-being may suffer if you can’t get your hair to grow back on its own.
Some cultures associate losing hair with aging and other stereotypes. This can be devastating for someone going through medical, hormonal, or age-related hair loss. Healthy hair regrowth may help you regain the confidence you lost.
Hormones
Your hormones are chemical messengers that regulate all of your body’s processes. Hair growth is tied to your hormones, and any fluctuations or declines in certain hormones can lead to losing hair. Think about post-pregnancy hair shedding; this happens because your body’s cascade of pregnancy hormones changes.
Hormonal changes as you get older can affect your hair. Age-related hair loss and thinning primarily affect women due to declines in estrogen production, but this problem can affect men as well.
Genetic Baldness
Male-pattern baldness is passed down through families. If you carry the gene for this condition, you may experience very early balding, starting in your 20s or 30s. This can change your appearance and make you feel older than you really are.
There are no ill physical effects from male-pattern baldness besides losing hair. However, you may experience poor mental health as a result of your unwanted early hair loss and thinning.
There is no cure for male-pattern baldness, but you can take steps to treat it. Regenerative medicine is here to intervene and treat hair loss in a natural, science-based way.
ExogroPro: The Latest in Hair Regrowth Science
When you experience hair loss of any kind, you probably have two priorities — prevent further hair loss and replenish your missing hair. ExogroPro, a professional-grade hair loss solution, addresses both of these problems at once.
How It Works: Preventing Further Hair Loss and Regrowing Lost Hair
ExogroPro works to stimulate your hair follicles, causing them to grow healthy hair again. This treatment uses the power of specific exosomes, which carry materials between your cells.
ExogroPro is designed to send signals to your hair follicles that stimulate hair growth. Because of exosomes’ extracellular communication abilities, they may be able to revive “dead” hair follicles on your head.
Because of this treatment’s therapeutic effects on hair follicle health, it may help prevent further hair loss and thinning. By rejuvenating your hair follicles and preventing them from going dormant, ExogroPro offers a possible solution to unwanted lost hair.
The Procedure: What to Expect
The premium patent pending ExogroPro formula is injected into the scalp to deliver exosomes to the hair follicles. These exosomes originate from human stem cells, specifically mesenchymal stem cells. This is just another way we can harness the power of stem cells to regenerate and repair damaged tissues within your body.
After two to six months, you may notice your hair growing back thicker and fuller than before. The results window varies, but one thing is certain — hair regrowth is worth the wait.
The Benefits of Choosing Regenerative Medicine for Hair Growth
With many prescription hair growth drugs on the market, you may be wondering — why choose ExogroPro? Here are the major benefits of choosing regenerative medicine for hair regrowth and thickening.
May Be More Effective Than Traditional Treatments
There are numerous treatments for hair loss, including PRP injections, topical oils, and more. These have varying efficacy and likely won’t give you the results you’re looking for. Prescription-strength hair growth drugs may not work for you either, resulting in frustration and discouragement.
Regenerative medicine harnesses the power of science and innovation. By using human stem cells, we work with the body processes already in place within your system. Exosomes may prove to be more effective and efficient than other hair loss solutions.
Drug-Free Therapy
Exosomes are naturally found in the human body. When you choose ExogroPro, you choose drug-free natural therapy for your hair and scalp.
While prescriptions can be helpful for some people facing hair loss, it’s understandable to want a natural alternative. We work with your natural healing and regrowth processes, not against them.
Dual-Action Treatment: Prevention and Active Regrowth
It’s impressive to consider how ExogroPro not only prevents further lost hair but can revive faulty hair follicles. This dual mechanism is key to getting the full head of hair you’re after. If it works for you, you’ll no longer have to mourn the hair you’ve lost — you could potentially get it back!
Encourages Hair Health
Solving hair loss isn’t just about replacing lost hair. It’s also about growing healthy, strong locks that can withstand damage and remain intact. ExogroPro promotes hair follicle health by improving cellular communications in the injected tissues. What’s more promising than the idea of a full, healthy head of hair after hair loss and thinning?
Combating Hair Loss and Thinning with Medical Science
It’s important to seek evidence-based treatments for your hair loss. No matter what the root cause of your hair problems is, you may find regenerative medicine to be a viable solution.
You don’t have to mourn your lost hair forever. Regenerative medicine is at the forefront of medical innovation and science, which could spell good news for your hair.
by Stemedix | May 27, 2024 | Health Awareness, Neurodegenerative Diseases, Parkinson's Disease, Stem Cell Research, Stem Cell Therapy
Getting any serious medical diagnosis can be frightening and intimidating. You might be unsure of what to do next or how to manage your condition. When it comes to Parkinson’s disease, the future can be even more uncertain since it’s a progressive neurodegenerative condition. It’s important to make a plan for how you’ll proceed after receiving a Parkinson’s diagnosis. You aren’t alone on your journey. Here are some steps you can take after your doctor tells you that you have Parkinson’s disease.
Understanding Your Diagnosis
Before you make an action plan, you should fully understand your Parkinson’s diagnosis. It’s important to know how this disease can affect your physical, mental, and social health in the future.
Parkinson’s Symptoms
Every person with Parkinson’s experiences the disease slightly differently. However, there are some common symptoms to watch out for as the disease progresses.
Common Parkinson’s symptoms include:
- Muscle tremors
- Insomnia
- Muscle stiffness
- Slow movements
- “Shuffle walk”
- Hunched or stooped posture
- Small handwriting
- Sudden soft or low speech
- Mood swings
- Sudden weight loss
- Decreased appetite
- Poor balance and coordination
- Dizziness and fainting
These are just a few of the warning signs and symptoms that Parkinson’s is progressing. Often, motor symptoms are the giveaway that someone has Parkinson’s over other diseases. It’s important to get an official diagnosis from a physician before seeking treatment.
What Causes Parkinson’s Disease?
The cause of Parkinson’s disease is the degeneration of neurons in the brain that produce dopamine. Dopamine is a neurotransmitter that helps control voluntary movements, and without enough of it, your movements become uncoordinated or involuntary.
Researchers don’t yet know the exact cause of Parkinson’s. The disease may have genetic components, but it seems to appear in combination with environmental triggers.
Certain risk factors make it more likely for someone to develop Parkinson’s. These factors include being male or over the age of 60. However, these risk factors aren’t guarantees that someone will develop this disease.
Is There a Cure?
There is currently no cure for Parkinson’s disease. Since it’s a neurodegenerative condition, the neurons that produce dopamine will continue to die off over time. However, modern innovative treatments like stem cell therapy may slow the progression of your symptoms to improve your quality of life.
You can also make lifestyle changes to mitigate some of the movement-related symptoms of Parkinson’s. Exercise and a healthy diet can keep you in good physical and mental shape, giving you a better ability to fight this disease.
Start Tracking Your Symptoms
After you’ve been diagnosed with Parkinson’s disease, you should start tracking your symptoms. Whether you use an app or a paper journal, it’s important to notice trends and patterns in your symptom development. These records will also help your doctor or Parkinson’s specialist come up with the best treatment plan for you.
You can break your symptoms down by category — movement, cognition, speech and swallowing, and other common groups of Parkinson’s symptoms. Then, record the date and severity of each symptom, noting any concerning developments along the way.
It may give you a greater sense of control and autonomy to keep track of what’s happening in your body as the disease progresses.
Piece Together a Treatment Team
Your doctor or Parkinson’s specialist may already have a treatment team for you, but if not, consider taking the steps to make your own. This may mean visiting different offices, seeking alternative therapies, and communicating with other Parkinson’s providers.
The more professionals you have on your side, the more robust and effective your treatments can be. Encourage your treatment team to communicate via medical charting or telephone so everyone can be on the same page. Always report any changes to your treatments to your primary care doctor or Parkinson’s specialist.
Get Plenty of Exercise and Gentle Movement
One of the best ways to slow the progression of Parkinson’s and retain your motor skills is to exercise. Whether you choose low-intensity activities, like walking or gentle stretches, know that you’re making healthy choices for your body.
The more your brain and body connect to produce voluntary movements, the stronger those connections become, which may help delay the onset of more severe movement symptoms. If you’ve never been physically active, now is the time to start.
There are low-impact exercises that don’t put stress and pressure on your joints. These include swimming, cycling, yoga and stretching, and elliptical workouts. Don’t feel like you have to push yourself to the max — any movement at all is healthy for you.
Improve Your Nutrition
The foods you eat play a large role in how you feel. If your diet is full of processed and refined foods, you may experience inflammation, fatigue, and other symptoms.
Eating a well-balanced diet with plenty of fruits and vegetables can keep you in good shape. Fruits and vegetables contain antioxidants, which are natural substances that fight aging and tissue damage.
If your goal is to slow the progression of Parkinson’s, incorporating more of these whole foods into your diet can’t hurt. See a registered dietician if you need help curating a healthy, well-rounded diet after a Parkinson’s diagnosis.
Evaluate and Try Different Treatments
Parkinson’s has no cure, but there are interventions and medical therapies that may help with your symptoms. From prescribed medications to holistic therapies to regenerative medicine, your options are plentiful.
Regenerative medicine, in particular, may offer surprising positive results for your Parkinson’s symptoms. Interventions like stem cell therapy for Parkinson’s may help reverse some of the cellular damage caused by this disease. These treatments get to the root cause of your symptoms and have the potential to improve your quality of life.
Physical therapy and speech therapy can be helpful for many Parkinson’s patients. These interventions help you regain motor control and improve your speech once the disease has started to interfere with these functions.
Staying Hopeful After a Parkinson’s Diagnosis
It’s important for you to have a strong support system, both medically and socially, to get through Parkinson’s disease. While it can be difficult, staying hopeful and cultivating gratitude can keep your mind in a positive place as you fight these symptoms. Never give up on yourself and your health, even if you’ve been diagnosed with a neurodegenerative condition.
by Stemedix | May 20, 2024 | Multiple Sclerosis, Age Management, Health Awareness, Regenerative Medicine, Stem Cell Research, Stem Cell Therapy
Some health conditions don’t yet have definite cures. Multiple sclerosis (MS) is one of them. While there is no known cure, several new treatments are emerging that show great potential in treating MS. Stem cell therapy for multiple sclerosis can be life-changing. If you struggle with debilitating symptoms and everyday life is painful for you, regenerative medicine may be able to help. Here’s everything you need to know about using stem cell treatments to address MS symptoms.
Multiple Sclerosis: Causes and Symptoms
Multiple sclerosis is a complex disease that researchers are still studying. Knowing the potential causes and common symptoms can help you monitor your condition and recognize when to seek treatment.
How MS Develops and What Causes It
Multiple sclerosis is a neurodegenerative disease. Your immune system starts attacking your nervous system, causing damage over time. Specifically, your immune system degrades the protective coating on your nerves. This coating is called the myelin sheath, and it’s essential for proper nerve function.
The faulty immune response in patients with MS is triggered by certain environmental factors that turn on specific genes. In other words, you may be genetically predisposed to MS, and certain environments “switch on” the genes that activate the disease.
Scientists don’t yet know exactly what causes this activation, but it may be related to lifestyle factors. Smokers and people with inflammatory diets are at higher risk for developing this condition.
Common MS Symptoms
You may experience a combination of common MS symptoms. Certain symptoms may flare up and then go away for a while. During flare-ups, you’re more likely to experience pain and discomfort.
The most common symptoms of multiple sclerosis include:
- Numbness and tingling
- Vertigo
- Skin conditions
- Balance problems
- Difficulty with coordination
- Problems swallowing
- Trouble speaking
- Vision disturbances
- Eye pain
- Seizures
- Hearing problems or loss
- Intense nerve pain
Since MS affects your nervous system, it makes sense for it to impair your balance, coordination, and senses. This disease may eventually affect your optic nerve, or the nerves involved in hearing and auditory processing.
How MS Can Progress Without Treatment
You aren’t doomed to a life of pain and suffering if you’ve been diagnosed with MS. However, it can be a progressive neurodegenerative disease if left untreated.
Some patients experience a steady progression in sensory and motor problems because of MS. Others will have periodic flare-ups that go away and come back randomly. You may notice that stress, lack of sleep, and poor nutrition trigger flare-ups for you.
If left completely untreated, the protective coatings on your nerves will start to degrade, and the affected nerves will stop working properly. This is what leads to trouble swallowing, walking, speaking, seeing, and hearing.
Innovative treatments like stem cell therapy may improve your prognosis with MS. Regenerative medicine may help repair some of the nerve damage caused by your immune responses, addressing the root cause of your symptoms.
What Is Stem Cell Therapy for MS?
Stem cells are known for their ability to regenerate and repair tissues in the body. In lab environments, stem cells can be “programmed” to develop into the necessary cells needed for wound healing, tissue regeneration, and reducing inflammation.
These restorative cells can also renew themselves, keeping injured and diseased areas supplied with plenty of stem cells to continue healing and repairing themselves. That’s why stem cell therapy is so potent — once the stem cell repair process starts, it can continue on its own.
Multiple sclerosis leads to nerve and tissue damage over time, and stem cells may be able to reverse some of that damage. By modulating your immune responses, combating inflammation, and replacing damaged tissues, stem cells can significantly improve your MS symptoms.
The Benefits of Stem Cell Therapy for Multiple Sclerosis Patients
You have several options when it comes to MS treatments. There are medications and alternative therapies designed to combat MS symptoms and nerve damage. However, stem cell therapy offers unique advantages you should consider before selecting your treatment(s).
Drug-Free Therapy
Stem cells are not pharmaceutical compounds. They are natural cells every human body produces and keeps around for wound healing and tissue repair. Since this therapy is drug-free, there are fewer risks involved — like medication side effects and allergies.
Some patients choose to take MS medication in conjunction with stem cell therapy. Only you can decide what treatment routes are best for you. However, if you want to go drug-free, stem cell therapy is a potent option for you.
Get Behind the Symptoms
Regenerative medicine does more than just mask your symptoms or cover up pain. It gets to the root causes of your MS challenges, including nerve damage and inflammation. By using stem cells to target areas of damage and discomfort, you may be able to improve your future with this disease.
Innovative Treatments
Regenerative medicine is at the forefront of medical science. Researchers are learning new information about MS and stem cells every year, and you can be a part of this experience. By choosing stem cell therapy, you get to benefit from the latest advancements in natural healing and recovery.
Slower Disease Progression
Since MS can be progressive, it’s important to seek treatment as soon as possible. Stem cell therapy may prevent your symptoms from getting worse and debilitating you, as well as improve your future health outcomes with Multiple Sclerosis. Whether you suffer from periodic flare-ups or progressive degeneration, regenerative medicine can help.
Navigating Your Future With MS
It can be devastating to receive a diagnosis like multiple sclerosis. However, it’s important not to lose hope. As medical science progresses forward, there are new and innovative treatments around every corner.
Regenerative medicine gives you the opportunity to take advantage of the latest advancements in this area of science and research. You can use it in conjunction with other interventions as specified by your physician.
No matter what treatments you choose to battle your MS symptoms, know that you’re never alone. Your condition does not define you.
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