by admin | May 30, 2018 | Health Awareness, Multiple Sclerosis
Vitamin D is a naturally-occurring nutrient found in certain foods, and the body can also attain it through sun exposure. Deficiencies in this crucial nutrient can cause bone and muscle pain, and over time, may also be linked with increased risks of cardiovascular disease, cognitive impairment, and certain types of cancer. Additionally, vitamin D aids in calcium regulation and is therefore essential for maintaining healthy bones.
While vitamin D intake has been hailed by medical experts as a means of supporting overall wellness for years, researchers have recently begun to compile even more reason to load up on the vitamin: it could possibly aid in the prevention of Multiple Sclerosis (MS).
The Link Between Vitamin D & MS
One compelling piece of research supporting a connection between MS and vitamin D is the higher concentration of individuals with the disease living in areas that receive less sunshine. Now, further research performed by the University of Oxford shows a “substantial evidence base” linking vitamin D and MS. While the average odds for a UK citizen to develop MS are one in 1,000, the odds for individuals with the gene variant DRB1*150 jump to one in 300. The study’s findings show that vitamin D plays an integral role in the functionality of the DRB1 gene. Thus, maintaining adequate levels of the vitamin could lower a person’s risk of developing MS.
Yet, what does this mean for people who are already living with MS? More than 2.5 million people suffer from the disease worldwide, and it is the most common disabling neurological condition in young adults. It turns out vitamin D may also have beneficial effects on individuals with MS, too. According to additional studies, the nutrient could help alleviate the severity and frequency of symptoms. MS causes the immune system to attack nerve cells’ protective layers, but because vitamin D has a positive effect on a person’s immunity, taking it regularly could aid in symptom management.
A Staggering Deficiency
While the benefits of getting enough vitamin D are clear, a deficiency among a large percentage of the population remains. More than 41% of U.S. adults are deficient, while it’s estimated 1 billion people across the globe have inadequate levels of the vitamin in their blood.
The deficiencies could result from a few factors. For one, many people have become more diligent about limiting exposure to UV rays in an attempt to lower skin cancer risks. Additionally, the vitamin is only found in limited types of food, including spinach, kale, fatty fish like tuna and mackerel, cheese, and egg yolks.
Nonetheless, even individuals with dietary restrictions and safe sun practices can use supplements to increase their intake. While the National Institutes of Health recommends a daily intake of 600 IU for individuals between the ages of 19 and 70, you can consult with your physician before beginning a daily supplement regimen for a precise recommendation.
by admin | May 2, 2018 | Multiple Sclerosis
Multiple Sclerosis (MS) patients can experience exacerbations, also known as flare-ups, and they can vary for each person. Some can be intense while others are mild. Some bring on new symptoms while others may worsen old ones. A true flare-up lasts at least 24 hours and has been 30 days from the previous attack.
These exacerbations are caused by inflammation in the central nervous system which damages the myelin causing disruption in the transmission of nerve impulses resulting in symptoms of MS. Common symptoms experienced during a flare-up may include dizziness, balance problems, numbness, pain, blurred vision, fatigue, and pins and needle sensations. MS patients can treat symptoms which can shorten flare-ups and recover faster, but how can you avoid flare-ups? WebMD offers some helpful tips on how to prevent but each person is an individual who has their own triggers to relapsing attacks.
Take Your Medicines
Ensure you take the prescription medicines given by your physician. These medicines will help prevent you from a possible relapse and from your symptoms from getting worse. If some side effects are seen due to the medicine, talk to your physician for other options.
Maintain Your Health
A bladder infection or a flu are trigger examples to a flare-up. It is important to maintain healthy habits so you can avoid these triggers. Some suggestions are to diligently wash your hands, avoid anyone who is sick, get a flu-shot, and stay hydrated while maintaining a routine to avoid bladder infections.
Quit Smoking
In general, smoking is not good for overall health and it can make MS symptoms worse. Studies have shown that by quitting smoking, you can slow the progression while also preserving cognitive functions. One study conducted by the Menzies Research Institute in Australia showed that persons who smoked the equivalent of two packs per day accumulated three times as much disability as those who smoked less than a pack per day. It is best to consult with your doctor to discuss the best options for you to quit.
Relax
For some, stress can also be a cause for a flare-up. Keep down stress levels by practicing methods such as yoga, meditation, or activities that help you feel relaxed and help you unwind.
Rest
Sleep deprivation is common in people with MS due to symptoms like muscle spasms and pain that can keep one up at night. Some medications can also disrupt the sleep patterns. Consult with your physician to help manage symptoms and discuss changes in medication to help allow for a restful night’s sleep.
These tips will hopefully help you in prevention of flare-ups. However, when they do present themselves, it is important to keep your physician updated so they can help treat for faster recovery while also reducing the inflammation. Your doctor may prescribe a steroid to tone down the inflammation, but some patients can be overly sensitive to steroids. They may have side effects like mood changes, weight gain, stomach issues and sleep deprivation. In these cases, your doctor can help with alternatives such as Achtar gel which is injected into muscles to decrease the inflammation.
by admin | Apr 26, 2018 | Health Awareness, Multiple Sclerosis
Maintaining a healthy and nutritious diet is important in managing the symptoms of Multiple Sclerosis (MS). MS occurs when the body’s own immune system attacks the central nervous system. This can lead to potential symptoms such as numbness, fatigue, vision problems, bowel and bladder dysfunction, and movement challenges. Following a healthy diet can help play a significant role in dealing with these symptoms.
The National Multiple Sclerosis Society advises that there is no specific diet that can help cure MS since the symptoms of this condition tend to come and go. This makes it challenging to measure the effectiveness of any specific diet. However, following a diet that is low-fat and rich in fiber can be beneficial in helping with MS symptoms. Healthline has suggested some foods for those with Multiple Sclerosis to avoid or incorporate into a daily diet that may be beneficial.
Avoid Saturated Fats & Add Vitamin D
For good overall health, it is best to reduce fat intake to as low as 15 grams a day. You do not want to eliminate good fats or avoid cutting down in too many foods that contain Vitamin D. Some studies conducted by researchers at the University of Oxford and another conducted at the New Jersey Medical School have suggested that maintaining adequate levels of vitamin D may have a protective effect and lower the risk of developing MS and lessen the frequency and severity of symptoms. Some common foods that contain Vitamin D are liver, cheese, egg yolks and fatty fish like tuna and salmon.
Just Say No to Caffeine and Diet Drinks
Drinks that contain caffeine and aspartame can be a cause of irritation to the bladder. According to the nutritional guidelines provided by researchers, it is best to avoid such drinks especially if you experience bladder related symptoms.
What About Gluten?
A study that was published revealed that MS patients had high sensitivity to gluten. Before switching to a gluten free diet, have this tested to see if you do have an allergy to gluten. Gluten intolerance is a wheat-related disorder. Symptoms, including belly pain and bloating, occur after eating foods that contain gluten, such as, wheat, barley, and rye.
Opt for Fruit Instead of Refined Sugars
There is no evidence today that shows that refined sugar may lead to MS flare-ups, however, it is still suggested to cut back on sweet sugary foods to help manage a healthy weight. Additional intake of calorie rich food and sugar can lead to weight gain which has been linked to MS fatigue. It’s okay to have a slice of birthday cake once in a while but it is highly beneficial if you can choose fruit instead of food that contains refined sugar. Additionally, fruits are rich in fiber to help with constipation which can be a common symptom for MS patients.
Eat Well, Feel Good, and Live Long
Unfortunately, Multiple Sclerosis is a lifelong disease where the types and frequency of symptoms vary for each individual. There are various ways to help manage symptoms in order to have a better quality of life. Having a low-fat, high fiber diet will help provide energy, relief of some symptoms, and prevent additional health problems like heart disease.
by admin | Apr 19, 2018 | Multiple Sclerosis, Stem Cell Research
Multiple sclerosis is a neurodegenerative disease that occurs when the immune system attacks the material that insulates nerve cells. As the immune system breaks down these myelin sheaths that coat the nerves, it becomes progressively more difficult for cells of the nervous system to communicate with one another. A new study on the potential use of stem cells to treat multiple sclerosis has led to promising results.
Because stem cells – and specifically, mesenchymal stem cells have been used to treat other immune conditions and inflammatory conditions successfully, scientists have reasoned that these stem cells may be able to help with multiple sclerosis. In this recent study, published in the Journal of Translational Medicine this year, scientists aimed to determine if umbilical cord mesenchymal stem cells are safe in patients with multiple sclerosis and if they may have any impact on the disease.
The study involved a full year investigation into 20 participants who had multiple sclerosis. The mean age for enrollees was approximately 41 years, and 60% of participants were female. One-quarter of the subjects did not take any medications for their multiple sclerosis over the course of the study. All subjects received seven infusions of stem cells over the course of one week. Their neurological and imaging tests to assess subjects’ neurological status were implemented before the infusions, as well as one month after and one year after the treatment.
The researchers determined that the stem cell regimen was safe, as no patients suffered any serious adverse side effects during the course of treatment. There were some complaints of headaches and fatigue, however. The researchers also concluded that the stem cell therapy was effective in helping the multiple sclerosis patients, as several of their scores improved one month after the treatment. In addition to performance measures, reported quality of life also improved with the treatment. Impressively, inactive lesions were observed in the majority of MRI scans of the brain and spinal cord (83.3%) one year after treatment.
Twenty percent of the participants reduced their medication in the follow-up period. These promising results suggest that stem cells may be able to help multiple sclerosis patients and that these types of treatments need to be further explored for their potential to help this set of patients.
by admin | Dec 11, 2017 | Health Awareness, Multiple Sclerosis
Holiday season can be a stressful time especially for those with Multiple Sclerosis (MS). Changes in schedule, travel, and demands of daily routines may add stress that can possibly cause the worsening of symptoms.
Below are some tips offered by health specialists that can help avoid possible disease flares and increase of symptoms.
Set Realistic Expectations
Help set realistic expectations during the merriment that can be easily managed. Avoid activities that are risky and be mindful to not do more activity than what you are normally accustomed to.
Communicate with Family and Friends
Communicate openly on how you are feeling to your friends and family. Some symptoms aren’t visible to them, so it is very important to let them know if you are not doing or feeling well. Don’t hesitate to ask for help.
Pace Yourself
Fatigue can be an impact for those with MS. Help to prioritize your activities during the holiday season. Set a reminder to take a nap or rest to recharge yourself.
Travel Arrangements
Travel may cause disruption in your eating, medication, and sleeping schedules, so plan carefully. Both air and ground travel can also require special type of arrangements to be available, such as easy access to bathroom. Carry a doctor’s letter that shows your need to use injection medicine while traveling on a plane as the Transportation Security Agents (TSA) may require this confirmation.
Challenging Routines
Normal routine disruptions can be expected and may be troublesome for those with a neurological disorder. Consider the possible complications that can arise due to changes in sleeping and eating routines. Family and friends can help maintain lesser disruptions and stress by asking what normal eating and sleeping routines are and try to provide as close to that schedule as possible.
Emotional Outbursts
Holiday season can be, at times, an emotional time for everyone. Due to neurological issues, some MS patients may have emotional outbursts like sudden crying or laughing. Help educate family and friends what may be happening and that it is ok. It is important for them to feel comfortable and know that these emotional outbursts may be involuntary due to extreme reflexes experienced by the patient.
Manage Coordination
Know your physical limitations and be mindful to not overextend yourself. If you love to cook, but due to your condition are unable to stand steady by the stove or struggle with cutting food due to numbness of hands, then try to participate by reading out the recipe to a family member. If in a new environment, it is helpful for family members to remove clutter and other items that may disrupt movements.
Sensitivity to Temperatures
Temperature sensitivity is another common symptom for those battling MS. Friends and family can help to maintain the temperature of the home so it is not too warm nor too cold. Be sure to stay warm if travelling to a colder environment for the holidays.
by admin | Nov 21, 2015 | Multiple Sclerosis, Stem Cell Research, Studies
At 6 months post-treatment, neurological improvement or stabilization was observed from all (99) patients in the study except one.
In their recently published study, Long-term outcomes of autologous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis: physician’s and patient’s perspectives, published in the Annals of Hematology Journal, Shevchenko et al. describe the effects of an autologous hematopoietic stem cell transplantation (AHSCT) with high-dose immunosuppressive therapy (HDIT) on 99 patients with multiple sclerosis. That the stem cell transplantation is autologous means that the stem cells derive from the patient’s own body, and the stem cells being hematopoietic indicates that the stem cells give rise to blood cells.
The idea for this type of therapy for multiple sclerosis has stemmed from the fact that multiple sclerosis is characterized by nervous system inflammation. Because inflammation results from activities of the immune system, it has been thought that targeting the immune system to reduce its activity could improve symptoms of the disease. More specifically, this particular combination therapy, using AHSCT and HDIT, has been aimed at destroying the immune system and rebuilding a separate system from hematopoietic stem cells so that the new immune system functions more favorably in those with multiple sclerosis.
AHSCT and HDIT have been used in the treatment of multiple sclerosis for several years, but the specific way these techniques are able to improve multiple sclerosis is not well understood. Further, there is some debate about both the safety and effectiveness of these treatments. Small sample sizes and homogeneous patient groups have plagued many of the studies performed to address these issues. In the present study, however, the researchers studied patients with different types of multiple sclerosis. This experimental structure allowed the scientists to show that AHSCT and HDIT used in combination can help those with both remitting and progressive multiple sclerosis and that the positive effects on the disease appeared to endure over long-term periods. At 6 months post-treatment, neurological improvement or stabilization was observed from all (99) patients in the study except one. The average follow up time for patients was 62 months, or just over 5 years, and up to and at this point, 47% of patients demonstrated significant improvement jumping at least 0.5 points on the Expanded Disability Status Scale EDSS scale. These results are highly informative for physicians treating patients with multiple sclerosis and are a promising demonstration of the potential for stem cells to improve conditions like multiple sclerosis.
Learn more about stem cell therapy for Multiple Sclerosis.
- Reference
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Shevchenko, J. L., et al. “Long-term outcomes of autologous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis: physician’s and patient’s perspectives.” Annals of hematology 94.7 (2015): 1149.
- Study Abstract
St. Petersburg, Florida
