Mesenchymal Stem Cells

Mesenchymal stem cells interacting with immune cells in autoimmune disease research
Illustration of mesenchymal stem cells interacting with immune cells.

Mesenchymal Stem Cells and Autoimmune Disease

Autoimmune and autoinflammatory diseases are driven by complex changes in immune regulation. Standard treatments can reduce disease activity, but many conditions remain difficult to control and may require long-term immunosuppression. A peer-reviewed review published in Frontiers in Immunology examines how mesenchymal stem/stromal cells (MSCs) interact with the immune system and why they are being studied…

Why Mesenchymal Stem Cells Have Regenerative Potential

Mesenchymal stem cells have proved to be one of the most promising stem cell types for regenerative medicine. A recent review has compiled information from studies looking specifically at how these stem cells can be used for regenerative cell therapies. According to the authors of this review, as part of the effort to characterize mesenchymal…

Mesenchymal Stem Cells and Neurodegenerative Diseases

As the name suggests, neurodegenerative diseases are a disease of the nervous system in which nerve cells (i.e. neurons) become dysfunctional and die. As more nerve cells die, certain brain functions slow, change or stop. Alzheimer’s disease, Parkinson’s disease, Huntington’s disease and Amyotrophic lateral sclerosis (ALS) are examples of debilitating and even fatal neurodegenerative diseases.…

Biomedical illustration of mesenchymal stem cells modulating inflammation in COPD and lupus research

Literature Review: How Mesenchymal Stem Cells Modulate Systemic Inflammation in COPD and Lupus

Published: August 2026 | Category: Autoimmune & Respiratory Research Reviewed Evidence Reviewed Study 1: A Placebo-Controlled, Randomized Trial of Mesenchymal Stem Cells in COPD Authors: Weiss DJ, Casaburi R, Flannery R, LeRoux-Williams M, Tashkin DP Publication & Date: Chest. 2013;143(6):1590-1598. DOI / Link: https://doi.org/10.1378/chest.12-2094 | PubMed Reviewed Study 2: Effect of Mesenchymal Stromal Cell Infusions…

Umbilical Cord MSC-Derived Exosomes and Spinal Cord Injury: A Promising First Step

Umbilical Cord MSC-Derived Exosomes and Spinal Cord Injury: A Promising First Step

Exploring New Possibilities for Spinal Cord Recovery Spinal cord injuries can have lasting effects on movement, sensation, and independence. Because the spinal cord has a limited ability to repair itself, researchers continue to explore regenerative approaches that may help support recovery. One promising area of research involves exosomes derived from human umbilical cord mesenchymal stem…

MSC-Derived Extracellular Vesicles and Cartilage Repair: A New Look at Osteoarthritis Research

MSC-Derived Extracellular Vesicles and Cartilage Repair: A New Look at Osteoarthritis Research

A Simpler Look at Osteoarthritis Osteoarthritis is a common joint condition that can cause pain, stiffness, swelling, and reduced mobility. It is often thought of as “wear and tear,” but it is more than just aging joints. Osteoarthritis can also involve inflammation, cartilage breakdown, and changes in the joint environment that make healing more difficult.…

Umbilical Cord MSC Exosomes and Disc Health: A New Look at Back Pain Research

Umbilical Cord MSC Exosomes and Disc Health: A New Look at Back Pain Research

Why Disc Degeneration Matters Back pain and neck pain are extremely common, and one major contributor is intervertebral disc degeneration. The intervertebral discs sit between the bones of the spine and help absorb shock, support movement, and keep the spine flexible. Over time, these discs can lose structure, hydration, and strength. When this happens, it…

Placenta-Derived MSCs and Limb Circulation: Early Research in Critical Limb Ischemia

Placenta-Derived MSCs and Limb Circulation: Early Research in Critical Limb Ischemia

When Poor Circulation Becomes Serious Critical limb ischemia, often called CLI, is a severe form of poor blood flow in the legs or feet. It can happen when arteries become blocked or damaged, preventing enough oxygen-rich blood from reaching the tissues. For patients, this can lead to serious symptoms such as: Standard treatments may include…

Umbilical Cord MSCs and Stroke Recovery: Exploring New Support for Neurological Healing

Umbilical Cord MSCs and Stroke Recovery: Exploring New Support for Neurological Healing

Life After an Ischemic Stroke An ischemic stroke happens when blood flow to part of the brain is blocked. Even after the immediate medical emergency is treated, many people continue to live with lasting effects. These may include weakness, changes in movement, trouble with coordination, speech challenges, reduced independence, and lower quality of life. Recovery…

Umbilical Cord MSCs and Transplant Recovery: A New Look at Immune Support

Umbilical Cord MSCs and Transplant Recovery: A New Look at Immune Support

A Challenge After Stem Cell Transplant Stem cell transplants are used to treat certain blood cancers, including acute leukemia. During this type of treatment, healthy blood-forming stem cells from a donor are given to a patient to help rebuild the blood and immune system. When a perfectly matched donor is not available, doctors may use…

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