MSC - Page 25

A Review of Current Mesenchymal Stem Cell Clinical Applications

Human mesenchymal stem cells (hMSCs) are multipotent adult stem cells found in tissue throughout the body, including in the umbilical cord, bone marrow, and adipose tissue. Capable of self-renewing and differentiating into multiple tissues including bone, cartilage, muscle, fat cells, and connective tissue[1], MSCs appear to have a wide range of potential for use as…

A Review of Current Perspectives of Regenerative Medicine in Orthopedic Surgery

It is estimated that over 126 million Americans, or nearly one in two adults, are affected with some form of regenerative medicine for musculoskeletal injuries disorder, condition, or injury - a number comparable to the percentage of the population currently living with a chronic lung or heart condition[1]. While there are a number of treatment…

Examining the Beneficial Effects of Autologous Mesenchymal Stem Cell Transplantation in Active Progressive Multiple Sclerosis

Typically understood to support hematopoiesis and to produce the cells of the mesodermal lineage, mesenchymal stem cells (MSCs) found in bone marrow, fat, and other tissues of the body, have recently been found to contain additional properties that include immunomodulator and neurotrophic effects. Considering earlier studies that have demonstrated favorable effects of MSC treatments in…

Regenerative Medicine Can Help to Treat Rheumatoid Arthritis

There are a number of things that can cause arthritis, a painful condition that causes stiffness in joints. In Rheumatoid Arthritis (RA), the body’s immune system attacks the regenerative medicine for musculoskeletal injuries system, causing inflammation that leads to arthritis pain. Over time, RA can cause a number of problems, including cartilage deterioration, swelling, and excess…

Can Stem Cells Help Manage Chronic Orthopedic Problems?

Orthopedic conditions can present many challenges to patients. Chronic orthopedic problems often result in ongoing pain and discomfort. Traditional medical approaches to injuries and joint-related ailments often require painful surgeries. These invasive procedures can involve difficult and extended recovery times. Common examples of orthopedic problems include: Bursitis Osteoarthritis Rheumatoid arthritis Osteoporosis Pain from injuries Fortunately, many…

Exploring The Role of Stem Cells and Regenerative Medicine In Treating Lung Disease

For patients facing a lung disease, including COPD, current and traditional therapeutic options may not be as effective in managing symptoms or slowing the progression of the condition so researchers have turned their attention to the potential benefits of stem cell therapy for COPD and ex vivo lung bioengineering in hopes of developing new and…

Advancing Stem Cell Treatment for Traumatic Brain Injury

According to the CDC, in 2019, traumatic brain injury (TBI) contributed to nearly 61,000 deaths in the United States alone[1]. While there are several clinical treatments designed to address the neurological dysfunction after sustaining a TBI, including hyperbaric oxygen, brain stimulation, and behavioral therapy, none appear to produce satisfactory or lasting results. In recent years,…

Using Mesenchymal Stem Cells for Musculoskeletal Regeneration in Clinical Applications: Current Status and Perspectives

Research exploring the benefits of mesenchymal stem cells (MSCs) has demonstrated tremendous potential as a regenerative therapy option for the musculoskeletal system. Research into these cell-based regenerative therapies is promising, and they must continue to provide the data necessary to show their therapeutic potential in clinical settings.  In this review, Steinert et al. review and…

Using Mesenchymal Stem Cells As A Therapeutic Strategy for Neurodegenerative Diseases

Neurodegenerative disease is a broad term encompassing a number of chronic, progressive diseases that result in degeneration and or death of neurons; these diseases include stem cell therapy for Parkinson disease’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS) and affect over 50 million Americans each year[1][2]. Since neurons possess a very limited…

Studying the Potential of Human Stem Cells for Treating Glaucoma

Glaucoma is a group of eye conditions that damage the optic nerve and lead to progressive, irreversible loss of vision. With over 80 million people affected by the condition, glaucoma is the second-leading cause of blindness, behind only age-related macular degeneration. Although there are several different risk factors, the most understood and treatable risk factor…

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