Stem Cell Therapy

Exosome-Facilitated Spinal Cord Injury Repair: Advancing a Therapeutic Modality

Clinical Evaluation of Exosomes for Treating Low Back Pain: A Comprehensive Review

Low back pain is a widespread issue that affects millions of people worldwide, significantly impacting their daily lives and placing a substantial financial strain on the healthcare system. Existing treatment options for low back pain often provide only temporary relief and come with various limitations. With the increasing interest in regenerative medicine, newer treatments like…

CELLTOP Clinical Trial: Phase 1 Findings on Adipose-Derived Stem Cell Therapy for Spinal Cord Injury Paralysis

Alcoholic Liver Disease (ALD): An Overview and Emerging Treatments

Alcoholic liver disease (ALD) is a serious global health problem that arises from chronic or binge alcohol consumption. As a chronic liver disease, ALD occurs due to alcohol's harmful effects on the liver, which is the first organ to metabolize alcohol. This process leads to the production of harmful byproducts that damage liver cells and…

Adipose-Derived Stem Cells: A Promising New Approach for Treating Secondary-Progressive Multiple Sclerosis

Multiple sclerosis (MS) is a chronic disease that affects the central nervous system, leading to a range of physical and cognitive impairments. There are different types of MS, with the most common being relapsing-remitting MS (RRMS) and secondary progressive MS (SPMS). RRMS is primarily an inflammatory condition, while SPMS involves a progressive decline due to…

Exploring Stem Cell Therapy for Progressive Multiple Sclerosis

Progressive multiple sclerosis (PMS) is a complex, disabling form of multiple sclerosis characterized by the progressive accumulation of central nervous system (CNS) damage. This damage arises from chronic inflammation, demyelination, axonal injury, neuronal degeneration, and gliosis, affecting both white and gray matter in the brain and spinal cord. Despite advancements in MS research, effective reparative…

Evaluating Stem Cell Therapy for Degenerative Disc Disease and Low Back Pain

Back pain is the most common cause of disability worldwide, impacting people of all ages and socioeconomic backgrounds. In North America, it is one of the top reasons people miss work and visit doctors. Studies show that at least 80% of Americans will experience low back pain at some point in their lives, making it…

Clinical Application of Mesenchymal Stem Cells in Autoimmune Conditions

The onset of autoimmune diseases is related to unbalanced immune homeostasis and leads to the injury and failure of several organ specific tissues. Currently estimated to affect 8-10% of the population, these autoimmune diseases are associated with serious impairment, high mortality rate, and significant medical costs. The discovery of stem cells, and specifically mesenchymal stem…

Chondrocyte and Mesenchymal Stem Cell-Based Therapies to Help Manage in Osteoarthritis and Other Orthopedic Conditions 

Osteoarthritis (OA) continues to be the most common form of degenerative joint disease in the United States and around the world.  According to the World Health Organization (WHO), 528 million people worldwide were living with osteoarthritis (OA) in 2019, which is an increase of 113% since 1990. The Global Burden of Disease Study 2021 found…

Advancements in Mesenchymal Stromal Cell Therapy for Cartilage Regeneration in Knee Osteoarthritis

Osteoarthritis (OA) is a prevalent and disabling joint condition that imposes significant health and economic burdens globally. Between 2006 and 2016, the global percentage change in years lived with disability due to OA increased by 31.5%. Knee osteoarthritis (KOA) is the most common form, primarily affecting older adults and those who are obese. Symptoms of…

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