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What Are Adult Stem Cells?

What Are Adult Stem Cells?

Stem cells are essential in understanding human development, disease, injury, and potential treatments and cures. However, since the initial research on these critical cells began with embryonic stem cells, many people dismiss the benefits of stem cell research and treatment as controversial. Unfortunately, that dismissal ignores what may be of adult stem cells, which are more commonly used in therapies today. Adult stem cells provide the same benefits as embryonic stem cells but with some limitations. 

What Are Stem Cells?

Stem cells are unique cells found in the human body that are the only cells that can differentiate into new cell types. Depending on the need, stem cells can divide and create brain, muscle, and blood cells, as well as various other specialized cells in the body. This ability earned them the label of the “building blocks of cells.”

Stem cells may also help repair damaged tissues, allowing them to play a critical role in managing condition and injury symptoms.

What Are the Types of Stem Cells?

There are two primary forms of stem cells – embryonic and adult. 

Embryonic Stem Cells

Embryonic stem cells come from a blastocyst, an early-stage embryo before it implants. In the very early days of forming a human, cells reach a blastocyst stage, which occurs about four to five days after fertilization. 

Embryonic stem cells are particularly valuable since they can divide unlimitedly under the right conditions. Since these are the very first cells the body forms to make a human, they can become all types of cells. In addition, they are pluripotent, meaning they can become many types of cells. 

The embryonic stem cells used in research now come from unused embryos donated from in-vitro procedures.

Adult Stem Cells

Adult stem cells have two main types. One type of adult stem cell comes from tissue inside the body, such as bone marrow, fat tissue, or skin tissue. However, the number of stem cells in these tissues is limited, and they can only differentiate into specific types of cells, making them multipotent, not pluripotent. 

Scientists have discovered ways to change adult stem cells in a lab to make them pluripotent, like embryonic stem cells. These are induced pluripotent stem cells, and they still come from adult tissue. 

Stem Cell Therapy

Currently, physicians and scientists may use hematopoietic stem cells (HSCs) or mesenchymal stem cells (MSCs) to help manage conditions. HSCs are adult cells found in the bone marrow. Recently, researchers have found strong evidence that HSCs are pluripotent and may serve as the source of most cells in the body. MSCs are a multipotent cell that can differentiate into different tissues in the body and are found in adipose (fat), umbilical cord, and bone marrow tissues. 

While the early years of stem cell research focused on embryonic stem cells, researchers are now uncovering the capability of adult stem cells and discovering new and exciting ways to help patients with managing their conditions and injuries with these unique cells. To learn more about the services offered at Stemedix, contact us today!

What Is the Most Effective Treatment for Osteoarthritis?

What Is the Most Effective Treatment for Osteoarthritis?

Osteoarthritis is the most common form of arthritis, affecting 32.5 million adults, according to the Centers for Disease Control and Prevention. This condition appears most often in the hands, knees, and hips. It causes the cartilage inside a bone to start to break down, changing the bone itself. There are many treatment options for osteoarthritis, but one of the most promising for managing symptoms and possibly even reducing the condition’s effects is regenerative medicine, also known as stem cell therapy. 

What Is Osteoarthritis?

Osteoarthritis is an incurable and chronic degenerative disease of the joints. With time, the cartilage that works to cushion the ends of the bones begins to wear down. Ligaments and tendons break down, as well, and inflammation increases. 

Some of the most common symptoms of osteoarthritis include the following:

  • Loss of flexibility
  • Joint pain
  • Joint stiffness
  • Joint tenderness
  • Grating sensations
  • Swelling

People who have joint or stress injuries, who have a genetic predisposition to osteoarthritis, or who are obese are at a higher risk of developing this condition. It is also more common in women than in men. 

There are two types of osteoarthritis. The first type is primary osteoarthritis, which affects the fingers, hips, knees, spine, and big toes. 

Secondary osteoarthritis appears with a pre-existing joint abnormality from trauma or injury. It can also stem from inflammatory arthritis, infectious arthritis, metabolic disorders, or genetic joint disorders. 

Regenerative Medicine for Osteoarthritis

Stem cells are cells that are not mature. They can divide and change into different cells with specialized functions. Using adult mesenchymal stem cells instead of embryonic cells is the most common option for osteoarthritis. These stem cells are present in bone marrow, umbilical cord, and fat tissues.

By using stem cells, it is possible to promote the regeneration of cartilage. This regeneration can help reduce pain while also improving joint function. 

Stem cells have the capability of replacing damaged cells anywhere in the body. Depending on the tissue that surrounds them, stem cells can become bone, cartilage, tendon, muscles, or fat.

These cells also release anti-inflammatory factors to combat pain and support healing. When injected into the joints, they can potentially improve flexibility and movement. 

Choose Stem Cell Therapy for Osteoarthritis Relief

Although stem cell therapy is a new and alternative option for the treatment of conditions like osteoarthritis, it shows promising results. Stem cell therapy has the ability to reduce symptoms of this degenerative disease, helping you regain movement in the affected joints while reducing pain. If you would like to learn more about how stem cell therapy can help with the treatment of osteoarthritis, contact Stemedix today!

Stem Cell Therapy for Fibromyalgia

Stem Cell Therapy for Fibromyalgia

Fibromyalgia is often misunderstood and misdiagnosed. It’s estimated that up to 2% of adults in the United States suffer from the condition, with women affected almost twice as frequently as men. Here we will learn about Stem Cell Therapy for Fibromyalgia.

What Is Fibromyalgia?

Fibromyalgia is a medical condition where sufferers experience widespread pain throughout their bodies. In addition, they can also endure sleep disturbances, fatigue, and emotional and mental distress.

Patients with fibromyalgia may also be more sensitive to pain, a condition called abnormal pain perception processing. While the origin of fibromyalgia is unknown, experts believe a malfunctioning nervous system may be the cause. 

What Is Stem Cell Therapy?

Stem cell therapy is a form of regenerative medicine aimed at managing the root cause of pain and disease. Stem cells lie dormant throughout the body until they’re activated as part of a healing response. 

Mesenchymal stem cells are different from other cells found in the body, as stem cells are the only cells that can differentiate into specialized cells instead of solely producing more stem cells. 

When stem cells divide, they can create another stem cell and a specialized cell, like a blood cell or a muscle cell. The specialized cell can then heal or replace damaged cells. 

How Can Stem Cell Therapy Treat Fibromyalgia?

Current treatments for patients with fibromyalgia include prescription and over-the-counter medications, stress management techniques, cognitive behavioral therapy, and exercise. While these treatments are often effective, they don’t address the underlying cause of fibromyalgia. 

However, many studies examining stem cells for managing fibromyalgia offer promising results. In addition, stem cell therapy’s potential in managing autoimmune disorders may also provide the key to fibromyalgia treatments. 

Stem cells possess immunoregulatory properties that help to manage the body’s immune response and reduce inflammation. Patients with conditions aggravated by inflammation, especially those in the nervous system, may find relief as the inflammation subsides.

Specifically, stem cell therapy treatments targeting neuroinflammation in the brain may offer the potential to correct signals in the nervous system and reduce abnormal pain perception processing. 

Additionally, stem cells release growth factors or cytokines into their injection points. The growth factors serve as part of the process of replacing damaged cells. Researchers believe that patients with fibromyalgia may have a unique cytokine profile that increases inflammation. 

Explorations in stem cell therapies for fibromyalgia show that the new cytokines may repair and replace the pro-inflammatory cytokines aggravating the condition. 

Fibromyalgia Patients May Soon Find Relief

As studies and trials exploring the benefits of stem cell therapy in managing fibromyalgia continue, patients may soon have a new treatment option that targets the cause of the condition instead of simply managing symptoms. Patients are already beginning to see results in several preliminary treatments. If you would like to learn more about Stem Cell Therapy for Fibromyalgia, contact us today at Stemedix!

How Do You Know If You Have Degenerative Disc Disease?

How Do You Know If You Have Degenerative Disc Disease?

According to the Medical Advisory Secretariat, approximately 40% of people over 40 have degenerative disc disease. It is not easy to know that you have disc disease because its development is gradual and can present with related problems, like herniated discs and spinal stenosis.  To diagnose Degenerative Disc Disease, your doctor can perform a number of procedures and tests. Learn more about them as well as the symptoms that accompany this condition.

Symptoms of Degenerative Disc Disease

Most people’s spinal discs show signs of wear as they age, but not everyone develops degenerative disc disease. People who have this condition experience symptoms like:

  • Numbness and tingling in extremities
  • Pain that worsens when sitting, bending, twisting, or lifting
  • Decreased pain when lying down 
  • Weakness in legs
  • Foot drop (difficulty lifting the front part of the foot)

There can also be periods of severe pain that can last for a few days or even a few months. The pain can affect the buttocks, thighs, lower back, or even the neck, depending on the affected discs. 

Neurological and Physical Examinations

To diagnose degenerative disc disease, your doctor will perform a neurological exam. They will test your reflexes and muscle strength, determine whether there are other nerve changes, and record how your pain spreads. 

They will then observe your posture and perform a physical exam. They will feel your spine to check its alignment and curvature, and they will also feel for muscle spasms. 

Imaging Tests

An exam can contribute a lot of data that can inform a diagnosis, but spinal imaging is crucial to determine a confirmed diagnosis of degenerative disc disease. X-rays allow your doctor to see whether there are any narrowed spinal channels, bone spurs, fractures, or osteoarthritis.

Your doctor may also request a CT scan or an MRI. These tests are more effective than standard X-rays for seeing soft tissues in your spine. With this more advanced imaging, your doctor can see if you have any herniated or bulging discs. 

They can also perform a discogram, a procedure that involves injecting dye into one of your discs. If there is a problem with the disc, it will leak the dye. 

Finally, the doctor may perform a test known as a myelogram. This time, dye is injected into the area around your spinal cord, allowing your doctor to see if you have a spinal cord disorder

Do You Have Degenerative Disc Disease?

If you suspect you may have degenerative disc disease, reach out to professionals to get the right diagnosis. Only then can you find the options for treatment most suitable for alleviating the painful symptoms you feel. Many patients have discovered regenerative medicine, also known as stem cell therapy, as a potential option to help manage their degenerative disc disease. Stem cells have the properties to help repair and replace damaged tissues allowing for a healing cascade to eliminate pain and inflammation. If you have Degenerative Disc Disease and you want to learn more about the options available at stemedix, contact us today!

Can Regenerative Medicine Help Spinal Cord Injuries?

Can Regenerative Medicine Help Spinal Cord Injuries?

When someone sustains a spinal cord injury, they may believe there is little to be done in terms of treatment. In the past, treating spinal cord trauma has been focused on providing support to the patient and accommodating any limited capabilities caused by the injury. Treating spinal cord injuries often involves mobility aids, physical therapy, and daily medications. While these are all essential aspects of spinal trauma care, they do not make any significant improvement to the injury itself.

The Latest Research

New research shows that future treatment of spinal cord injuries could actually focus on resolving the symptoms caused by the injury and restoring certain functions within the spinal cord itself. A recent clinical study shows that there could potentially be a treatment for these kinds of injuries after all. A clinical trial out of Mayo Clinic has taken a look at the effect of regenerative medicine, also known as stem cell therapy, on patients with spinal cord injuries, and the results were promising.

The clinical trial, known as CELLTOP, used intrathecal injections of autologous adipose-derived stem cells to treat patients with traumatic or severe spinal cord damage. They found that when patients received these stem cells, they saw an improvement in certain symptoms associated with their spinal cord injury. This included motor and sensory function, with increased strength in fine muscle movement.

One patient in these trials who had sustained a grade A cervical spine injury was treated with stem cell therapy and saw an improvement in motor and sensory function. Another patient experienced an increase in their fine motor skills, with an improved ability to grip and pinch with his fingers.

How Does Stem Cell Therapy Work to Improve Spinal Cord Injuries? 

While clinical trials are still continuing, research shows the potential link between stem cells and spinal cord trauma. It may be found in how stem cells interact within the spinal cord microenvironment. In these clinical trials, stem cell therapy has been shown to potentially reverse the microenvironment and resolve certain symptoms of spinal cord injury.

When a spinal cord injury occurs, it results in complex pathophysiology. After the initial injury, there are microenvironmental changes that inhibit axonal regeneration. Stem cells can help reduce trophic support to an injured spinal cord’s microenvironment. This modulates the inflammatory response and suppresses cystic changes.

While many spinal cord injuries are still considered traumatic and severe, these CELLTOP clinical trials show promising treatment options in the future. Mayo Clinic is currently continuing this research to find how stem cell therapy can further benefit patients with spinal cord injuries. To learn more about how regenerative medicine can help spinal cord injuries, contact a care coordinator at Stemedix today!

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We'll send your FREE information packet that outlines our entire personalized, stress-free stem cell treatment process!

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We'll send your FREE information packet that outlines our entire personalized, stress-free stem cell treatment process!

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Request Information Packet

We'll send your FREE information packet that outlines our entire personalized, stress-free stem cell treatment process!

Thanks for your interest!

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We'll send your FREE information packet that outlines our entire personalized, stress-free stem cell treatment process!

Thanks for your interest!