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What Is Macular Degeneration & How Can You Prevent It?

What Is Macular Degeneration & How Can You Prevent It?

Age-related macular degeneration (AMD) is the most common cause of vision loss and affects more than 10 million people across the U.S., which is more than both glaucoma and cataracts combined. The condition is characterized by the deterioration of the central retina, or macula, which focuses on central vision. This important area of the eye enables reading, driving, recognizing faces and colors, and allows us to see objects in detail.

Although AMD is currently incurable, there are ways you can limit your risks, and if diagnosed, potentially control its progression. Discover more about the condition and key prevention strategies below.

What Causes AMD?

While the specific mechanisms behind AMD are still not conclusively known, experts are on the verge of making groundbreaking discoveries in the diagnosis and treatment of the condition. In particular, researchers from the National Institutes of Health (NIH) are exploring gene therapies as a prevention strategy, and have discovered that subtle gene alterations are responsible for 75% of a person’s risk for developing AMD. They have also pinpointed a daily regimen of vitamins and minerals which delays the onset of the more advanced phases of the condition by 25%.

How Can You Reduce Your Risk?

Although the definitive cause for AMD has yet to be discovered, there are known factors which are known to increase risk. For this reason, the following lifestyle modifications may be your best line of defense for preventing AMD:

  • Quit or Avoid Smoking: Research indicates that smoking doubles the risk of AMD, so if you haven’t already quit, make a plan to do so.
  • Control Your Blood Pressure: High blood pressure has body-wide implications, but in the delicate blood vessels in your eyes, its effects are especially pronounced. It is therefore essential for anyone experiencing hypertension to work closely with their doctors on controlling their blood pressure levels.
  • Exercise: Regular exercise has been shown to protect against AMD. In particular, sedentary individuals were four times more likely to get AMD than those who exercised lightly at least 10 hours per week or moderately for 8 hours each week.
  • Eat a Well-Balanced Diet: Based on the NIH’s AERDS study, experts believe high doses of critical nutrients, including vitamin C, vitamin E, beta-carotene, and zinc can slow the progression of both AMD and cataracts. This suggests nutrition may play a pivotal role in maintaining eye health with age, especially for at-risk populations including those with a family history of AMD.
  • Consider Supplements: While diet should be your primary source for vitamins and minerals, even healthy eating patterns leave nutritional gaps. Moreover, participants in the aforementioned AERDS study who benefited from increased vitamin intake were given high doses which would be impossible to obtain through diet alone. If you have been diagnosed with early-stage AMD or face an elevated risk for the disease, consider discussing your supplement options with your doctor.
Umbilical Cord Mesenchymal Stem Cells Show Promise in the Treatment of Multiple Sclerosis

Umbilical Cord Mesenchymal Stem Cells Show Promise in the Treatment of Multiple Sclerosis

A new study has shown that a protocol for treating Multiple Sclerosis with stem cells is safe. According to the researchers, the potential for using stem cells in Multiple Sclerosis therapy warrants further investigation. The results of the study were published in the Journal of Translational Medicine.

Stem cells – and specifically, mesenchymal stem cells, have been increasingly used in the treatment of immune and inflammatory conditions. Based on the success that has been seen in these areas, scientists reasoned that mesenchymal stem cells may also represent a useful approach to treat Multiple Sclerosis, a neurological disease that involves the abnormal attack by the immune system on the myelin sheath that insulates nerves and allows nerve cells to communicate effectively and efficiently with one another.

To test this idea, the scientists used umbilical cord mesenchymal stem cells in 20 Multiple Sclerosis patients. The patients were given intravenous injections of the stem cells each day for seven days. The researchers evaluated the patients – with both neurological testing and nervous system imaging – at baseline, one month after treatment, and one year after treatment. The researchers found that the stem cell treatment improved neurological scores in patients and that lesions in the brain and cervical spinal cord were inactive one year after the stem cell injections. There were no serious adverse side effects associated with the treatment.

Based on these findings, it is possible that stem cells will provide a useful treatment option for those with Multiple Sclerosis. With more research, we will better understand exactly how stem cells can be used to help this population of patients.

 

Reference: Riordan, N.H. et al. (2018). Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis. Journal of Translational Medicine, 16(57), 1-12.

Stem Cell Therapy for Sports & Athletic Injury

WHAT IS Regenerative Medicine for Sports and Athletic Injury Regenerative Medicine also known as Stem Cell Therapy for Sports and Athletic Injury is an alternative option to help manage symptoms. Request Information Packet WHAT IS Regenerative Medicine for Sports and...
Mesenchymal Stem Cell Options for Erectile Dysfunction

Mesenchymal Stem Cell Options for Erectile Dysfunction

Erectile dysfunction is the most common sexual disorder among men. During an erection, blood enters the tissues within the penis and is temporarily trapped there. In erectile dysfunction, however, this process does not occur. A man who suffers from this condition is unable to achieve a penile erection sufficient for sexual intercourse.

Erectile dysfunction has many causes ranging from neurological conditions to vascular (blood vessel) conditions to psychological conditions. In most men, erectile dysfunction is caused by a problem in blood flow and nitric oxide production, which is why drugs like the Viagra and Cialis are effective for some men because they temporarily reverse these problems.

Results from a review of 54 research studies showed that stem cell-based therapies may be able to reverse these effects on a more permanent basis. For example, mesenchymal stem cells were able to increase the number of enzymes that produce nitric oxide. Likewise, mesenchymal stem cells increased the size of penile tissue in older rats. Indeed, stem cell injections were able to restore erectile function in rats with diabetes.

Based on these laboratory results, researchers have conducted clinical trials using stem cells to treat men with erectile dysfunction. In one such trial, researchers used a person’s own fatty tissue (adipose) to generate stem cells. They then injected those cells into men with erectile dysfunction. Eight out of 11 men treated with stem cells regained erectile function. In another small study, eight men with profound erectile dysfunction in whom oral ED treatments failed received placenta-derived stem cells. Two of the patients were able to achieve and sustain erections six weeks after treatment while an additional patient was able to do so after three months.

Laboratory studies of stem cells in the treatment of erectile dysfunction are extremely promising. The clinical studies in this area are limited, and the results are somewhat less impressive. Nonetheless, as improvements and refinements are made to stem cell technology, this approach could offer hope to men with erectile dysfunction, especially those men who have not been helped by ED drugs.

Reference: Albersen, M. et al. (2013). Stem-cell therapy for erectile dysfunction. Arab Journal of Urology. 2013 Sep; 11(3): 237–244.

 

What is the Arthritis Diet?

What is the Arthritis Diet?

While arthritis is a chronic condition for which there is no cure, certain dietary changes can help to alleviate its symptoms by reducing inflammation, improving bone strength, and boosting the immune system. Following the anti-inflammatory arthritis diet recommended by the Arthritis Foundation Discover could help you control your joint pain and stiffness, along with other therapies. Discover which foods to prioritize, and just as importantly, which to avoid, in honor of National Arthritis Awareness Month this May.

The Anti-Inflammatory Arthritis Diet

Although there is no prescriptive diet recommended for people with arthritis to follow exclusively, the low-inflammatory Mediterranean diet has been shown in numerous studies to reduce pain and increase physical function in certain types of arthritis, including Rheumatoid Arthritis (RA). The Mediterranean diet emphasizes vegetables and fish, along with olive oils and other foods that can help control inflammation. Here are a few foods to consider eating regularly:

  • Fish: Salmon, tuna, sardines, and other cold-water fish have high concentrations of omega-3 fatty acids, which are known for fighting inflammation.
  • Colorful Fruits & Vegetables: Packed with antioxidants which support a healthy immune system and may combat inflammation, heavily pigmented produce like blueberries, blackberries, cherries, spinach, broccoli, and kale are great foods for filling your plate and snacking between meals.
  • Nuts & Seeds: Monounsaturated fats found in pistachios, almonds, pine nuts, and walnuts are excellent for reducing swelling in the joints. Plus, they’re filled with fiber to help keep you full.
  • Beans: Varieties like pinto, black, and garbanzo beans have both antioxidants and anti-inflammatory compounds, along with a high dose of powerful vitamins and minerals.
  • Olive Oil: A perfect addition to salad greens, extra virgin olive oil is minimally processed and a heart-healthy source of fats. It also contains oleocanthal, a compound known for reducing pain and inflammation.

3 Inflammation Triggers to Avoid or Minimize

While eating inflammation-fighting foods can help reduce swelling and pain in the joints, it’s important not to counteract the effects of your healthy dietary choices with foods known to trigger inflammation. Here are a few foods to avoid or have sparingly:

  • Added Sugars: Unlike the natural sugars found in the fruits listed above, processed sugars can spur the release of cytokines, the body’s inflammatory messengers. Avoid any packaged or prepared foods with ingredients ending in “-ose” on the label.
  • Saturated Fats: These fats are known for aggravating arthritis inflammation. Full-fat dairy, red meat, pasta, pizza, and many desserts are high in saturated fat, so try to reduce your consumption of these foods for better arthritis management.
  • Trans Fats: Meat and dairy contain trace amounts of trans fat, but it’s mostly found in foods as a result of a process that adds hydrogen to vegetable oil. Not only does this dangerous fat raise “bad” cholesterol levels, but it can also trigger inflammation. Steer clear of margarine, nondairy creamer, fried foods, and chips and baked goods with trans-fat.

While making dietary modifications to improve arthritis symptoms may seem daunting at first, the changes are worth making. Not only do the suggestions above help to control pain and swelling in the joints, but they can also contribute to a healthier lifestyle overall. If you’re considering an arthritis diet, consider speaking with your doctor about the best dietary choices to benefit your specific condition.

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