Spinal Cord Injury

Advancements in Mesenchymal Stem Cell Applications for Traumatic Spinal Cord Injury: A Systematic Clinical Review

Spinal cord injury (SCI) can lead to lasting health challenges, impacting motor, sensory, and autonomic functions. Recovery from such injuries is particularly difficult due to the central nervous system's limited ability to repair itself. As a result, scientists have turned to stem cell therapies, particularly mesenchymal stem cells (MSCs), as a potential solution to help…

Exosome-Facilitated Spinal Cord Injury Repair: Advancing a Therapeutic Modality

CELLTOP Clinical Trial: Phase 1 Findings on Adipose-Derived Regenerative Medicine for Spinal Cord Injury Paralysis

Administration of Adipose-Derived Mesenchymal Stem Cells via Intrathecal Injection for Traumatic Spinal Cord Injury

With over 290,000 people in the United States living with SCI and with roughly 17,000 new cases each year, spinal cord injury (SCI) is a serious condition that significantly impacts the lives of those affected.  Considering the complexity associated with SCI, current treatments for SCI continue to focus mainly on managing symptoms and providing physical…

Mesenchymal Stem Cells for Managing Spinal Cord Injuries

Nerve damage resulting from spinal cord injury (SCI) often leads to temporary or permanent loss of function and contributes to poor quality of life. Most common among males below 30 years of age, SCI recovery has been limited specifically as a result of the low growth capacity of neurons and a lack of nerve growth…

Utilizing Mesenchymal Stem Cells for Spinal Cord Injury Therapy

Spinal cord injuries (SCI) are the most serious complication associated with spinal injuries and often result in permanent damage to the nervous system. With nearly 300,000 people in the United States living with SCI, the inability to treat these injuries has a significant impact on physical, mental, and financial health.  Additionally, while 94% of those…

Phase 1 Clinical Trial Investigating the Use of Autologous Adipose Tissue-Derived Mesenchymal Stem Cells for the Treatment of Traumatic Spinal Cord Injury

With more than 17,000 people in the US sustaining a spinal cord injury (SCI) each year and an estimated combined cost to healthcare and the workforce exceeding $40 billion, the condition has significant personal and socioeconomic implications. In addition, SCIs have limited pharmacological treatment options to support the regeneration of nerve damage. Considering the limited…

Functions of Mesenchymal Stem Cells in Spinal Cord Injuries

Spinal cord injury is one of the most complicated and serious pathological impairments affecting the central nervous system. Since the human body is unable to regenerate and repair the spinal cord after injury, there is a high likelihood of suffering permanent damage and disability. Often compounding the issue of SCI, secondary events occurring after the…

Using Mesenchymal Regenerative Medicine for Traumatic Spinal Cord Injury

Spinal cord injury is a global term used to capture damage to the spinal cord resulting from trauma (typically in the form of car accidents, falls, or work-related injuries) or from disease or degenerative conditions.   Worldwide, it is estimated that up to 500,000 people suffer some type of spinal cord injury (SCI), with most resulting…

A Systematic Review of Mesenchymal Regenerative Medicine in Traumatic Spinal Cord Injury

Spinal cord injury (SCI) is a devastating pathological condition affecting motor, sensory, and autonomic function. Additionally, recovery from a traumatic SCI (TSCI) is challenging due to the central nervous system’s limited capacity to regenerate cells, myelin, and neurological connections.  While traditional therapeutic treatments have proven ineffective in assisting in recovery, mesenchymal stem cells (MSCs) hold…

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