CoQ10, Creatine, and Neuroprotection: What is the Link?

CoQ10, Creatine, and Neuroprotection: What is the Link?

Coenzyme Q10 (CoQ10) is an antioxidant occurring naturally in the body. It is critical to the growth and maintenance of cells and is found to be lower in individuals with conditions such as Parkinson’s disease and Huntington’s disease. Research shows that taking CoQ10 supplements in combination with creatine may benefit individuals with these neurodegenerative conditions – but why?

CoQ10 & Creatine

Both CoQ10 and creatine are commonly found in meat and seafood. The body produces creatine naturally as well, in the kidneys, liver, and pancreas. It is an amino acid located in the brain and muscles, where it is used for energy. Together, both CoQ10 and creatine have neuroprotective effects. When taken in conjunction, they have been shown to improve motor performance and reduce DNA oxidative damage. They work by protecting against dopamine depletion and reducing lipid peroxidation, or the cellular damage caused by free radicals. CoQ10 and creatine have also been shown to reduce the volume of lesions found on the striatum, a part of the brain responsible for many aspects of cognition, including motor and action planning and decision making. In conditions like Parkinson’s disease, this area of the brain is compromised, resulting in symptoms such as tremors and slow movement. With Huntington’s disease, the degeneration of brain cells in this area causes progressive dementia.

How Should I Take CoQ10 & Creatine?

While CoQ10 and creatine can be ingested through food, they are found in minimal amounts in nutritional sources. Thus, eating more meat or seafood alone is unlikely to help you produce more of the antioxidant and amino acid. With that said, findings suggest that they can be taken as supplements as a form of combination therapy to treat neurodegenerative diseases. Moderate daily doses of CoQ10 (500-800 mg) in contrast with high doses (2,700 mg) in particular have been shown to yield mild to moderate improvements in symptoms like fatigue and muscle tone. Creatine has been shown to provide benefits for patients suffering from muscle-related pain. Before taking either CoQ10 or creatine, it is important for patients to discuss proper dosages and potential symptoms with their physicians for their ensured safety.

 

Could Avocado Help to Manage or Prevent Neurodegenerative Diseases?

Could Avocado Help to Manage or Prevent Neurodegenerative Diseases?

Avocados have long been hailed as a food source rich in vital nutrients. Not only is it loaded with almost 20 vitamins, minerals, and phytonutrients, but it also has just 80 calories per serving. Yet, aside from its “superfood” status, could this unique stone fruit hold even more power to boost wellness? Research seems to suggest so.

Phytochemicals in Avocado

According to an article in Advances in Neurobiology, avocados’ high concentration of phytochemicals could play “a pivotal role in the prevention and cure of various neurodegenerative diseases.” Phytochemicals are biologically active compounds found naturally in plant sources, many of which have antioxidants and free radical scavenging effects. Research has also pointed to their ability to improve the functionality of the endothelium or the cells that line the interior of blood vessels. With a host of beneficial properties, they are shown to reduce risks for non-neurodegenerative diseases as well, including cancer, inflammatory conditions, and type 2 diabetes.

How Phytochemicals Benefit Neurodegenerative Diseases

What researchers are now discovering is that in addition to reducing inflammation and attacking free radicals, these phytochemicals also seem to specifically exhibit neuroprotective effects. Overproduction of free radicals can lead to oxidative damage to important biomolecules such as DNA and proteins, which eventually lead to the development of degenerative diseases. Reactive oxygen species resulting from free radical damage can also become active in the brain and neuronal tissue, leading to oxidative stress. Researchers have determined that oxidative stress is a causative agent behind the development of neuronal damage, which is present in neurodegenerative diseases such as Huntington’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and Alzheimer’s disease. Interestingly, studies show that the antioxidants found in avocados are unique, and have been shown to reduce neuronal death.

To maximize the benefits of avocados, the Food and Drug Administration (FDA) updated its daily recommended serving to 1/3 of a medium-sized fruit in 2016. This allows consumers to reap significant nutritional benefits from the antioxidative properties of Vitamin C, vitamin E, and other components without ingesting too many calories from fats. The creamy, fiber-rich fruit is often served atop salads, toast, and even enjoyed raw.

 

What Effects Do Pain Killers Have on Dementia?

What Effects Do Pain Killers Have on Dementia?

For years, medical experts have warned of the medical concerns associated with opioids, including depression, weakened immune system, and digestive issues. Now, however, new research shows that they could be particularly dangerous for dementia patients.

The Dangers of Painkillers for Dementia Patients

According to research presented at the Alzheimer’s Association International Conference, opioid-based painkillers can triple the side effects of dementia. Individuals taking the drugs experienced more pronounced personality changes, significant increases in confusion and sedation, and lower activity levels throughout the day.

In another study, researchers focused exclusively on known as “Z drugs,” which are currently given to hundreds of thousands of patients with dementia to promote sleep. Drugs under this category included zolpidem, zopiclone, and zaleplon. Findings revealed that patients on these drugs faced an increased risk of bone fracture, which contributes to an increased risk of death in people with dementia.

A Widespread Problem

Alzheimer’s, which is the most common form of dementia, currently affects an estimated 5.7 million Americans. Roughly half of the people living in care homes and suffering from this or another form of dementia experience pain to some degree, which can result from unrelated medical conditions such as arthritis. Unfortunately, as dementia patients face compounding communication challenges, treating their pain can become more difficult.

The study has prompted experts to explore other, non-pharmaceutical means of treating pain and sleep disorders in dementia patients. Alzheimer’s research group leaders believe that the solution lies in finding nondrug interventions to help manage pain and promote quality of life while minimizing serious side effects like those revealed by the study findings. Regenerative therapy may be an option to consider for those battling Alzheimer’s disease or dementia.

How Does Krill Oil Reduce Inflammation?

How Does Krill Oil Reduce Inflammation?

Many chronic conditions, including arthritis, are characterized by chronic inflammation. While inflammation is the body’s natural immune response to healing damage, chronic inflammation takes place even when there is no injury present. It plays a role in a host of diseases, including life-threatening conditions such as heart disease and diabetes.

Researchers suspect chronic inflammation is caused by a combination of contributing factors, including family history and diet. Interestingly, recent findings are suggesting that just as certain agents may promote an inflammatory response, others may also help to block it.

Krill oil, in particular, is one dietary source which may have the ability to neutralize pro-inflammatory activity. The oil is rich in omega-3, a natural compound with anti-inflammatory properties. While other types of fish oil share similar properties, krill oil, in particular, appears to have a greater potential to promote lipid catabolism, a process involved in the breaking down of fat. Because there is a known interplay between lipid catabolism and inflammation, krill oil’s ability to stimulate the process better than other supplements is noteworthy.

Research has shown that krill oil can reduce arthritis pain and intestinal inflammation. Individuals suffering from arthritic pain saw a reduction of inflammation after one month of taking 300 mg of krill oil daily. When taken in combination with hyaluronic acid and astaxanthin, additional anti-inflammatory compounds, arthritis sufferers reported pain levels were reduced by half within three months, and 63% of study participants reported being entirely pain-free.

If you think krill oil supplements could help to alleviate your arthritis pain or minimize inflammation from another chronic condition, speak to your physician. As with any vitamins, it’s a good idea to seek input from medical professionals before taking krill oil or other anti-inflammatory supplements to assess possible interactions and receive guidance on recommended dosages.

Small Changes that Make a Big Difference to Your Health

Small Changes that Make a Big Difference to Your Health

Keep Track of Your Weight

If you are on a quest to losing weight, keeping track of your daily weight may help. A study showed that those who successfully lost weight had been measuring their weight regularly and also had support from others who were trying to lose weight too. Keeping a track of your progress and making changes to your diet can be effective.

Practice Good Oral Health

Gingivitis and gum disease are linked to various problems like diabetes, heart disease, pregnancy complications and even pancreatic cancer. To lower the risk of gum disease, brush your teeth twice a day, floss on a regular basis and make sure to visit the dentist twice every year.

Wear Sunscreen

Wear a sunscreen daily, even in the winters, whether it is raining or snowing. Snow reflects almost 80% of the sun’s harmful rays through the clouds. Sunscreen helps prevent skin cancer and aging.

Eat Fish

Cold water fish like mackerel and salmon are highly rich in omega-3 fatty acids. They can also be found in walnuts and have been proven to reduce the risk of heart disease, stroke and also prevent dementia. Try consuming fish twice a week but if you are not fond of eating fish then you can also try supplements.

Exercise Daily

It is recommended to include 30 minutes of physical activity daily, to meet this requirement you can break these 30 minutes into smaller intervals. Try to include it in your daily routine by taking the stairs instead of the elevator, parking the car further from the entrance, or taking a walk to a nearby store instead of using the car. Regular exercise has proven to reduce the risk of diabetes, heart disease, cancer and anxiety.

Visit the Doctor Regularly

Visit your doctor regularly for tests that are appropriate to your age, genetic risks, sex and other factors. Many conditions like diabetes and heart disease can be treated successfully if they are diagnosed in early stages.

Keep a Food Diary

If you are trying to reach a healthy weight, keep a food diary to ensure more success. A study conducted on 1700 people showed that those who kept a daily food journal successfully lost almost 20 pounds, which was twice as much as those who did not.

Wash Vegetables and Fruits

Make sure to always wash fruits and vegetable before eating or cooking them. This reduces the chance of ingesting a bacteria or other chemical residue present. Wash them thoroughly even if you plan to peel them so the knife does not transfer any harmful bacteria from the skin.

 

 

 

Why is Magnesium Important?

Why is Magnesium Important?

What is Magnesium?

Magnesium is a mineral required by the body to work efficiently. It aids the body in carrying out almost hundreds of different processes like controlling how our nerves and muscles function. Magnesium keeps the bones strong, maintains good heart health and also keeps the sugar levels in the blood under control. It also maintains the vitality of the body. It is present in various drinks and foods but if your body requires more of it then your doctor can also suggest you take supplements. In this article, we review the benefits and sources of magnesium.

How Much is Required?

Grown men under the age of 31 require 400 to 420 milligrams of magnesium daily. An adult woman requires around 310 milligrams of magnesium and if she is pregnant then another 40 grams is needed. Children can require anywhere from 30 to 410 mg depending on their gender and age.  It is best to talk to their pediatrician to find out how much your child may require according to their need.

Are You Getting the Required Dose?

It is observed that two-thirds of the western world does not have the proper required intake of magnesium, this leads to a variety of health related issues like high blood pressure, diabetes and migraines. People who are older in ages tend to have a higher deficiency of magnesium than others because their bodies expel a large amount of magnesium than normal.

Can You Take Too Much Magnesium?

Healthy individuals can flush out any extra magnesium from the body through their kidneys but still, a very high intake of magnesium can lead to nausea and cramps. Taking magnesium as a supplement, it is best suggested to not take more than 350 mg per day. Be cautious when using antacids and laxatives that contain magnesium to avoid too much intake that may lead to sickness.

Benefits of Magnesium


Stronger Bones

Magnesium is required by the body to produce new bone cells, research also shows that magnesium protects the body against broken bones, bone loss, and osteoporosis. Studies have also revealed that women who have osteoporosis have a very low level of magnesium than normal.

Fights Inflammation

Inflammation is the reaction of the body’s immune system to heal the wounds and fight off viruses. But if the body is always under inflammation then this can lead to issues like diabetes, arthritis and heart diseases. Magnesium helps in the prevention of inflammation.

Protects the Heart

Magnesium aids in pumping the blood. The right amount of magnesium in the blood decreases the chance of a heart disease, stroke, and irregular heartbeat. Magnesium can also help maintain good cholesterol levels in the blood as well as relax the walls of the blood vessels to keep blood pressure under control.

Prevents Migraines

Magnesium can prevent blood vessels from tightening and lowers the pain chemicals in the brain. Low magnesium levels could make you more prone to getting migraines. A recommended dose of 400 to 500 mg of magnesium may help to keep migraines away. But consult with your physician to determine the right level for you.

Lowers Risks of Diabetes

Insulin is the hormone responsible for keeping the blood sugar levels under control. Magnesium aids insulin in working efficiently. Studies reveal that people who took the right amount of magnesium were least likely to develop diabetes or could improve symptoms of those with diabetes.

Food Sources of Magnesium


Nuts and Seeds

An ounce of cashews and almonds can give you almost 80 milligrams of magnesium. Other sources can include pecans, peanuts, flax seeds, pumpkins seeds and sunflower seeds. You can garnish a salad with these nuts and seeds, you will get a healthy amount of fats, antioxidants, and fiber that is heart healthy.

Whole Grains

Regarding nutrition, whole grains outweigh benefits than white bread. They are rich in fiber and magnesium. Just two slices of wheat bread can give you 45 milligrams of magnesium, half cup of oatmeal can give you 30 milligrams and half cup of brown rice contains around 40 milligrams of magnesium.

 

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