Recently a video went viral in which a man with Parkinson’s disease (PD) tries cannabis for the first time, placing a drop of cannabinoid oil (CBD oil) under his tongue. Within minutes, his symptoms improve significantly: the dyskinesia (involuntary muscle movements) disappears almost entirely, and his voice returns. The significant reaction to the drug begs the question: can cannabis be used to help manage PD?
Clinical Studies on Medical Marijuana for PD
Unfortunately, as the Parkinson’s Foundation points out, the clinical trials on using marijuana for PD have been incredibly varied. Some studies use as few as five participants, and as a result, fail to meet the minimum research standards needed to garner support among the medical community. That hasn’t stopped patients from seeking the treatment themselves, however: 95% of neurologists say their patients have asked for a medical marijuana prescription.
Moreover, groups like The Michael J. Fox Foundation, among others, have called for the reclassification of marijuana, which could make it easier to conduct research. Currently, marijuana is classified as a Schedule I drug by the federal government. Drugs within this category are deemed to have a high potential for abuse and no known acceptable medical applications. To complicate matters further, there is currently a lack of standardized or known doses for CBD, as well as variable concentrations of the active ingredient. Nonetheless, in low doses, CBD appears to be well tolerated, though it poses side effects such as cognitive changes, nausea, and dizziness.
How Does CBD Work?
We know that the chemicals in marijuana react with the brain’s cannabinoid receptors. What researchers are still working to figure out is precisely how CBD effects these receptors. Trials show mixed results: while some patients have experienced improved motor and non-motor symptoms, others did not experience improvement. Limited studies show decreases in psychosis and tremors, as well as improvements in quality of life.
Could Cannabis Be Right for You?
While incorporating any form of cannabis will likely not replace PD medications, it’s possible that patients may experience a reduction in symptoms with CBD use. If you’re considering this treatment, talk to your doctor, who can recommend a treatment regimen based on your needs.
Visit our website for available hemp extract products. Click here
Four out of five people with multiple sclerosis experience muscle spasticity. Muscle spasticity causes increased muscle tone, uncontrollable muscle contractions, and spasms. Like severe muscle cramps, muscle spasticity can be quite painful and is one of the most troubling symptoms of multiple sclerosis. Despite being so common and so troublesome, multiple sclerosis patients with muscle spasticity have few effective treatments options. In many cases, the muscle spasticity continues even after treatment with drugs such as baclofen or tizanidine. Not only are these drugs largely ineffective, in many cases they cause substantial side effects.
Marijuana has long been known to exert a muscle relaxing (anti-spasmodic) effect. As medical marijuana is becoming legal in more jurisdictions, researchers are now carefully studying the effects of the substances within marijuana. One important example is a study conducted by Spanish researchers. In 2010, Spanish drug authorities approved the use of an oral spray that contains a combination of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), two active substances found in marijuana (Cannabis sativa). Spanish authorities approved the use of this drug for multiple sclerosis patients with moderate to severe muscle spasticity who did not benefit from other antispasmodic drugs.
Dr. Lorente Fernández and other Spanish researchers were interested in learning whether this combination of THC and CBD was able to help multiple sclerosis patients with severe muscle spasticity. The scientists found that the combination of substances found in medical marijuana was effective in 80% of patients they examined. What is striking about this finding is that every patient included in this study had failed to find relief from other medical treatments of spasticity. In other words, they had difficulty in treating muscle spasticity. When viewed in those terms, an 80% effectiveness rate is extremely impressive.
Some patients withdrew from treatment because they felt that THC/CBD did not help them within the first 30 days of starting treatment or some experienced dizziness or weakness.
Muscle spasticity is one of the most common, most troubling, and most difficult to treat symptoms of multiple sclerosis. While traditional medical treatments often fail, the substances in medical marijuana may offer hope. This study illustrates that 4 out of 5 multiple sclerosis patients with difficult to treat muscle spasticity achieved relief from a combination of THC and CBD, substances found in medical marijuana.
Visit our website for available hemp extract products. Click here
Reference: Lorente Fernández et al. (2014). Clinical experiences with cannabinoids in spasticity management in multiple sclerosis. Neurologia. 2014 Jun;29(5):257-60.
Over 1 million patients worldwide have been treated with adult stem cells and have benefited from them. And nearly 20 000 adult stem cell transplants were performed in the United States in 2014 alone! How is that possible? What are stem cells? What do they do to your body? And why are so many benefiting from them? We take a look at these important questions surrounding the benefits of stem cells, as well as how CBD can help you get the most benefits from stem cells.
What Are Stem Cells?
Stem cells are a very special kind of human cells. They are cells of the body and are therefore somatic cells, found in your bone marrow and fat cells. They are a part of your body’s natural repair process. But why are they so special? Well, they have the ability to develop into many different cell types. This can range from anything from muscle, cartilage and even bone! Stem cells can divide and become differentiated, and are therefore used as a therapy called stem cell therapy. Stem cell therapy involves using a patient’s own stem cells to repair damaged tissues. When an organism grows, the stem cells specialize and take on specific functions, including skin, nerves, blood, muscle, and liver.
Because of their magical transformative powers, they have the potential to treat a number of diseases, including diabetes, Parkinson’s and even cancer. They also have the potential to treat a number of serious injuries, from a damaged knee, to even treating spinal cord injury! Eventually, they may even be used to regenerate entire organs, decreasing the need for organ transplants. Now that we know what stem cells are and how they work, let’s have a look at five of their biggest benefits.
1. Avoid Invasive Surgery and Related Risks
One of the biggest benefits of stem cells and using them in stem cell therapy is that it allows patients who would possibly have required heavy surgery to not have any such invasive surgery. Stem cell therapy uses material already in the patient’s body, which makes it minimally invasive and also cuts out the need for an overly stressful, invasive surgical procedure. Most stem cell therapy is performed as an outpatient procedure, i.e. you can just have it done in the doctor’s office! No need for an overnight hospital stay and those ridiculously high associated medical costs.
Your doctor will first conduct a bone marrow aspiration, in which he removes stem cells from an area of the body, such as the hipbone, through a long needle. These cells are then delivered to the area of injury. Once there they work their magic to create healthy new tissue to replace a damaged muscle, tendon, ligament, cartilage or bone. They become healthy new cells that your body desperately needs.
2. Minimal Procedure & Recovery Time
One of the greatest stem cell benefits is the minimal amount of time involved in the whole therapy, from the actual procedure to the recovery time required afterward. Procedures generally last from two to five hours, depending on the type of cell treatment being performed. After the minor procedure, your activity level may be a bit limited for the first week. This is merely to let the stem cell therapy process to work uninterrupted and without any possible inflammation. After just seven days you should be able to return to your normal activity! Your treatment will include some monitoring after the treatment, to ensure everything is working as it should.
3. Can Offer Pain Relief
Stem cell therapy is highly sought out by patients who experience chronic pain. As it should be! Because of stem cells’ ability to restore and regenerate, being used in pain management is a logical step. The use of stem cell therapy is being studied for a number of chronic pain conditions, particularly pain in the knees, hips, elbows, and back. Stem cell therapy can offer pain relief in the way that it reduces the inflammation which causes chronic pain. It also helps to heal regenerative conditions that lead to pain, such as arthritis. Promising results have been found in research into the use of stem cells to reduce arthritis pain. As every patient and their condition is different, long-lasting pain relief can never be guaranteed by any doctor.
4. No Risk of Rejection
When you receive stem cells from a donor, there’s always the risk that your body will reject them. Because the stems are coming from another person’s body, many complications can arise. The most common complication is called graft-versus-host disease. This is when blood cells formed from the donor’s stem cells believe your own cells are foreign and attack them. On the other hand, harvesting stem cells extracted from your own body to generate new cells and tissues means there is no risk of rejection!
5. Potential to Discover New Treatments
Because of the nature of stem cells, the possibilities for treating new diseases and finding new cures is endless. Stem cell therapy research provides great potential for discovering treatments and cures to a variety of diseases. Advanced research is going as far as limbs and organs being grown in a lab from stem cells, which are then used in transplants. With stem cells, scientists are able to test millions of potential drugs and medicine, without the use of animal or human testers.
How Can CBD Help with Stem Cell Treatment?
We’ve seen how amazing stem cells are. Now let’s have a look at how much more amazing they can be when combined with the effects of CBD! According to results from multiple trials, cannabidiol, or CBD, can help increase the number of stem cells growing within the body. CBD has even shown to positively contribute to the movement of the stem cells within the body. They can then do what they do best – help heal the body and reduce pain.
Nearly 20% of those who went through hematopoietic stem cell transplant (HSCT) used cannabis. Not only was it used to treat their physical and emotional pain, but it was also used in the hope that it will contribute to the replacement of bone marrow that has been destroyed by cancer. Because both CBD and stem cells have been seen to reduce pain, combined the possibilities for better treatments are endless.
How Can I Experience the Benefits of Stem Cells?
You’ve heard about the many benefits of stem cells. You’ve heard how popular it is. And you’ve heard the vast amount of injuries, diseases, and pain that it can treat. Perhaps it’s about time you had a look at it as a treatment for your condition. Whether you’re looking for an alternative treatment to your sports injury, your multiple sclerosis or your chronic fatigue syndrome, we’re here to help you along the way.
Get in touch with us to see if you are a candidate for Stem Cell Therapy. Also, check out our website shop to see available products.
Multiple sclerosis (MS) is a debilitating neurological condition. MS causes nerve cells to become dysfunctional. The symptoms of multiple sclerosis vary from person to person and over time; however, one of the most common symptoms of MS is muscle spasticity. More than 80% of patients with MS have some degree of muscle spasticity.
Muscle spasticity causes increased muscle tone. Affected muscles contract even though the person is not trying to contract them. Patients may also experience uncontrollable muscle jerking and spasms. These muscle contractions can be quite painful and interfere with daily activities. In fact, about one in 20 multiple sclerosis patients with muscle spasticity are completely disabled because of it.
It can be difficult to treat muscle spasticity in patients with multiple sclerosis. Physicians may prescribe baclofen, tizanidine, or dantrolene for muscle spasticity; however, these treatments are only mildly effective and may cause troubling or serious side effects. Baclofen may cause muscle weakness, tizanidine may cause severe dry mouth, and dantrolene is toxic to the liver, for example. Researchers are continuously looking for ways to help multiple sclerosis patients to reduce muscle spasticity.
Cannabinoids are the biologically active chemicals found in the cannabis plant. Cannabinoids have been used successfully for various medical purposes. For example, these agents have been used to treat nausea caused by chemotherapy and to stimulate appetite in patients with cancer. Patients with multiple sclerosis have reported that hemp extract helps relieve symptoms. Moreover, research studies have shown cannabinoids can protect nerve cells against damage. Based on these findings, researchers conducted a clinical trial to study the effect of cannabinoids on muscle spasticity in patients with multiple sclerosis.
A total of 630 patients with multiple sclerosis and muscle spasticity received the hemp extract or placebo for 15 weeks. The researchers then performed a number of objective tests to assess muscle spasticity. Patients who received the cannabinoids had fewer symptoms and less muscle spasticity at the end of the clinical trial compared to patients taking the placebo. The greatest benefit appeared after 40 weeks of treatment. Indeed, patients felt that cannabinoids helped manage their condition. Importantly, no major safety concerns were reported.
These clinical trial results suggest long term cannabinoids treatment is safe and may help people with Multiple Sclerosis control symptoms of muscle spasticity.
Visit our website for available hemp extract products. Click here
Reference: Zajicek et al. (2005). Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up.Journal of Neurology, Neurosurgery, and Psychiatry. 2005 Dec;76(12):1664-9.
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