Using Ozone Therapy to Reduce Oxidative Stress Associated  with Chemotherapy-Induced Peripheral Neuropathy

Using Ozone Therapy to Reduce Oxidative Stress Associated with Chemotherapy-Induced Peripheral Neuropathy

Significant advances in the treatment of cancer have increased the number of cancer survivors while also allowing survivors to live longer and with overall improved quality of life. However, these treatments have also resulted in an increase in the number of survivors now living with their debilitating side effects, the most prominent being chemotherapy-induced peripheral neuropathy (CIPN). 

According to the American Cancer Society, CIPN often occurs when nerves located outside the brain and spinal cord are damaged as a result of chemotherapy treatments[1]. One of the many symptoms associated with CIPN is chronic oxidative stress, which results in a significant increase in free radicals and proinflammatory cytokines throughout the body. Common side effects of CIPN include dysesthesias, pain, anxiety, depression, insomnia, and fatigue.

It’s estimated that up to 85% of cancer patients are treated with neurotoxic chemotherapy, and up to 100% of those treated with platinum-based drugs (such as cisplatin, carboplatin, and oxaliplatin), develop CIPN. Not only does CIPN significantly affect a patient’s quality of life, should it develop during cancer treatment, the condition often interrupts and/or delays scheduled chemotherapy sessions.

This review, authored by Clavo et al., examines current cancer treatments potential mechanisms that could result in CIPN, summarizes current CIPN prophylactic and treatment approaches introduce and describes the role of ozone therapy in modifying oxidative stress and inflammation (with a specific focus on how it relates to CIPN), and summarizes experimental and clinical trials using ozone therapy to address the symptoms of CIPN.

Through the course of their review, the authors conclude that while there are several medications and therapies designed to address the inflammation and oxidative stress associated with CIPN, the results of their effectiveness in achieving the desired and/or intended effect(s) have been inconclusive. As a result, the authors conclude that prophylactic and therapeutic approaches to CIPN continue to be limited in both numbers and efficacy.

Ozone therapy is the process of introducing ozone gas into the body to treat an existing disease or medical condition. According to a study published in Medical Gas Research[2], ozone, when introduced into the body, creates higher concentrations of red blood cells, increases oxygen levels in the body, and produces an anti-inflammatory response. This process, when used to treat CIPN, is thought to be potentially effective in addressing the symptoms of the condition by inducing adaptive responses of tissues within the body.

The authors conclude their review by describing their current research examining the effect of ozone therapy on the analytical and symptomatic evolution of patients with CIPN. Specifically, this research will explore whether or not a relationship exists between the basal levels in oxidative stress parameters, including hyperspectral imagines (HSI), and the quality of life and symptoms self-reported by patients. The authors also call for further research to better understand the role of oxidative stress in CIPN as well as the clinical role of its modulation.

Source:  (2021, March 10). Modulation by Ozone Therapy of Oxidative Stress in … – PubMed. Retrieved from https://pubmed.ncbi.nlm.nih.gov/33802143/


[1] (2019, November 1). What Is Peripheral Neuropathy? – American Cancer Society. Retrieved July 9, 2021, from https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/peripheral-neuropathy/what-is-peripherial-neuropathy.html

[2] (2018, September 25). Clinical utility of ozone therapy for musculoskeletal disorders. Retrieved July 9, 2021, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178642/

The Differences Between Prolotherapy, Prolozone, & PRP

The Differences Between Prolotherapy, Prolozone, & PRP

Many exciting strides are being made in the field of regenerative medicine. With the goal of repairing healing tissue through regeneration, this branch of medicine uses various approaches to treat chronic illnesses, address injuries, and promote overall wellness. Here’s a look into some emerging treatment options.

Prolotherapy

Also known as proliferation therapy or regenerative injection therapy, prolotherapy is a complementary approach used to treat joint and muscle pain. It works by injecting an irritant to the affected area, such as a tendon or ligament, to spur connective tissue growth. The irritant is typically a sugar solution, which triggers the connective tissue to grow and promote healing. Study results have been mixed and research into the treatment is ongoing. For instance, people with osteoarthritis in the knee saw significant improvements after receiving prolotherapy injections, but studies have been small thus far.

Prolozone

Prolozone combines neural therapy, prolotherapy, and ozone therapy by injecting anti-inflammatory medications, ozone, vitamins and minerals, and other proliferative agents to promote healing. It’s believed the injected nutrients could bypass the body’s inflammatory response, thus enabling healing without added inflammation. Noticeable improvements have been reported by patients with osteoarthritis, though as with prolotherapy, most experts agree further research is needed to fully document the treatment’s effects. Other conditions that could respond well to prolozone may include rotator cuff injuries, sciatica, sports injuries, and chronic back pain, among others.

PRP

Platelet rich plasma (PRP) leverages the healing properties within a patient’s own blood, which is put through a centrifuge to isolate the plasma. PRP is concentrated and has growth factors that can help promote healing when re-injected into areas of tissue damage. This alternative option can help manage the symptoms of joint and musculoskeletal pain and can also be used in conjunction with stem cell therapy to drive optimal outcomes.

For more health awareness blogs, please visit https://www.stemedix.com/blog.

A Guide to Medical Ozone Therapy

A Guide to Medical Ozone Therapy

For conditions such as chronic illness, finding a safe and effective treatment regimen can be challenging. Oftentimes, the medications prescribed only help to control symptoms, instead of addressing the disease itself. Moreover, they also tend to come with a host of side effects that may impact the quality of life. While it isn’t a cure-all, many patients have found relief with medical ozone therapy. This alternative therapy is becoming increasingly popular, thanks to its ability to rebalance bodily systems. Find out more about what the treatment entails here. 

What Is Ozone Therapy?

This medical treatment leverages a naturally occurring gas, ozone. Unlike oxygen, which has only two atoms, ozone has three. The extra atom is primed to break off and join other molecules in a process known as oxidation. This extra atom can lend itself to healing when used in medical applications. In fact, it’s been used by practitioners since 1871, when it helped to treat wounds of WWI soldiers. Within the past two decades, however, it’s made significant strides in the medical community.

How Is Ozone Therapy Administered?

Ozone can be administered either as a local or systemic treatment. A local treatment aims to heal an isolated area of the body, such as a sore in the mouth or damaged joint. Systemic treatments, on the other hand, aim to promote healing throughout the whole body. Blood treatments are examples of systemic ozone therapy.

Which Conditions Does Ozone Therapy Treat?

Ozone can be used in the primary medical industry to treat acute infections and chronic illnesses. It’s also used to improve symptoms in joint injures and to prevent or treat infections in the dental industry. Aestheticians use ozone in the cosmetic industry, too, as a means of addressing concerns like wrinkles and cellulite.

When applied systemically, the treatment can be used for many conditions. Some are:

  • Infections
  • Autoimmune diseases
  • Gastrointestinal illness, such as IBS
  • Mold toxicity
  • Lyme’s Disease

Patients with chronic pain and fatigue, heart disease, allergies, and Alzheimer’s disease may also benefit from ozone therapy. When administered locally, ozone helps to treat non-healing wounds, ulcers, and infections.

What Are the Benefits of Ozone Therapy?

Medical Ozone therapy is considered a powerful, effective treatment for several reasons. For instance, it could:

  • Improve circulation
  • Modulate the immune system by powering an underperforming immune system or rebalancing an autoimmune problem
  • Control oxidative stress, a primary cause of disease
  • Enhance oxygenation for overall better physical wellness and healing

In addition to the improvement of their symptoms, many people who undergo ozone therapy also enjoy benefits such as increased endurance, energy, cognitive function, and overall wellbeing, along with decreased pain levels.

Ozone therapy is an alternative therapy poised to rebalance complex bodily systems. If you think the treatment could be right for you, contact a Care Coordinator for a free assessment!

The Anti-Aging Power of Ozone Therapy

The Anti-Aging Power of Ozone Therapy

Ozone therapy is an umbrella term for the medical and aesthetic treatments which implement ozone, a gas with three oxygen atoms instead of two. The powerful agent has been studied for the treatment of numerous conditions and concerns, including age-related factors. Here we are going to talk about the anti-aging power of Ozone Therapy.

The Anti-Aging Power of Ozone Therapy is drawing attention in the anti-aging sphere, thanks to the availability of treatment and its ability to treat the root causes associated with many concerns of aging. For instance, the risk of chronic conditions such as rheumatic disease, diminished immune response, high blood pressure, and certain types of cancer increases as we age. In many cases, these conditions can be traced to a reduced oxygen supply, but increasing the body’s oxygen levels through ozone therapy may help to prevent them. Moreover, ozone therapy offers compelling benefits such as increased energy and overall rejuvenation.

How Does Ozone for Anti-Aging Work?

Ordinarily, oxygen has two atoms. When it passes through an electric coil, it separates into three atoms and becomes ozone. When administered to the body, ozone can target and destroy harmful agents such as viruses and bacteria. Once its work is complete, it reverts to oxygen, increasing overall oxygenation. 

Ozone gives the body the nutrients it needs to perform its best, increasing healing activities in the following key ways:

  • Improved circulation and oxygen supply
  • Liver detoxification
  • Reduced uric acid
  • Decreased cholesterol and triglycerides
  • Improved white blood cell activity
  • Improved cellular metabolism

There are several methods to apply ozone therapy, including topically and via injection. If you’re considering this treatment option, be sure to find an experienced clinic that thoroughly assesses your medical history and discusses the potential benefits of the treatment for your specific concern.  Contact a Care Coordinator today for a free assessment!

What Is the Cost of Ozone Therapy?

What Is the Cost of Ozone Therapy?

Ozone therapy is a cutting-edge treatment in which naturally occurring ozone gas is mixed with oxygen to potentially help treat chronic conditions and improve overall wellness. It reduces inflammatory markers which contribute to oxidative stress and impact immunity. For this reason, it also serves as a powerful line of defense against infections and can offer a host of other wellness benefits. Of course, just as you’d do before pursuing any treatment, you might first ask: What is the cost of ozone therapy?

How Much Does Ozone Therapy Cost?

First, it’s important to understand that there are several factors which can impact the cost of ozone treatment. For instance:

  • condition being treated
  • severity of the condition
  • location of the clinic
  • specific processes used

These may all influence the price of ozone therapy. Prices can vary significantly. For example, ozone injections administered for joint pain may cost $30 to $350 per session, whereas intravenous ozone therapy can range from $100 to $1,200. 

Regional differences can also make a tremendous impact on price variations. For instance, while a small clinic in Nebraska might only charge $20 to $30 for a joint injection, an in-demand clinic in a populated city might have more rigorous standards, and could therefore fall on the higher end of the price range. 

Does Insurance Cover Ozone Therapy?

Another consideration for the cost of ozone therapy is the fact that U.S. insurers won’t cover the treatment. While other nations may reimburse patients for the therapy, it is still a fairly new treatment and is thus the patient’s responsibility to pay for out-of-pocket in the U.S. With that being said, many patients are drawn to the benefits of the treatment, including the potential to delay or avoid invasive procedures, and the control of unfavorable symptoms for chronic illnesses. 

Ultimately, price is an important factor to assess when considering ozone therapy, but it’s only one piece of the puzzle. To make an informed decision as to whether or not the treatment is right for you, be sure to screen potential providers to ensure they have stringent measures in place that promote optimal clinical outcomes and take into consideration every patient’s unique circumstances. Contact a Care Coordinator today for a free assessment!

Ozone Therapy for Autoimmune Conditions: What You Should Know

Ozone Therapy for Autoimmune Conditions: What You Should Know

People with autoimmune conditions face significant challenges. Their symptoms may range from uncomfortable to debilitating, and oftentimes, the medications used to control them are ridden with unfavorable side effects. Understandably, these patients often seek alternative treatments to address their pain without further diminishing their quality of life. One such treatment is ozone therapy.

Ozone Therapy for Autoimmune Disease

While ozone therapy is in many ways an innovative treatment, the medical field has been leveraging its capabilities for over a century. In the 1840s, ozone was first used to disinfect hospital rooms. During the first World War, it was used to help clean wounds. Ozone doesn’t require harsh chemicals to kill bacteria; its unique molecular structure (three oxygen atoms instead of two) gives it the ability to seek out and destroy pathogens. The third atom breaks off, oxidizing the phospholipids and lipoproteins of the bacteria or other harmful agent. 

With these unique capabilities, ozone therapy is a powerful option for treating autoimmune conditions such as lupus and Lyme disease. When the ozone runs through a person’s circulatory system, it kickstarts the immune system by triggering the release of key hormones and proteins. In doing so, it helps to regulate the immune response, thereby alleviating symptoms without the need for harsh drugs. 

Although ozone therapy isn’t a cure-all, it does present an option for those seeking an alternative treatment for their autoimmune disease to help improve their quality of life. If your symptoms haven’t subsided through traditional means or you’ve been frustrated by the side effects of medications, this treatment could offer a new alternative worth exploring. Contact a Care Coordinator today for a free assessment!

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