Stem Cell Research

Effects of Mesenchymal Stem Cell-Derived Paracrine Signals and Their Delivery Strategies

Mesenchymal stem cells (MSCs) have been widely studied and increasingly recognized as a potential therapeutic with the ability to initiate and support tissue regeneration and remodeling. While over 1100 clinical trials have been conducted to assess the therapeutic benefits of MSCs, there continues to be widespread variation surrounding the potential treatment outcomes associated with these…

Stem Cells for Transverse Myelitis

Patients suffering from uncommon conditions, such as transverse myelitis, often have limited treatment options, since these conditions lack the funding and the research needed to understand the disease and its causes. Here we will discuss stem cells for Transverse Myelitis. Regenerative medicine, also known as regenerative medicine, unlocks a new understanding of conditions and treatments.…

Allogeneic Bone Marrow-Derived Mesenchymal Stem Cell Safety in Idiopathic Parkinson’s Disease

Research has shown neuroinflammation to have a significant role in the pathogenesis of Parkinson’s disease (PD). Much of this same research has also demonstrated mesenchymal stem cells (MSCs), and specifically, allogeneic bone marrow-derived MSCs, can be effectively used as an immunomodulatory therapy for the potential treatment of PD. The goal of Schiess et al.’s study…

Bone Marrow-Derived MSCs to Reduce Neural Damage and Prevent Multiple System Atrophy

Multiple system atrophy (MSA) is a rare, degenerative adult-onset neurological disorder that affects your body's involuntary functions, including blood pressure, breathing, bladder function, and motor control. MSA also demonstrates several symptoms similar to those accompanying Parkinson’s disease, including slow movement, stiff muscles, and loss of balance[1]. Considering the rapid and fatal progression of MSA, there…

Mesenchymal Stem Cells in Multiple Sclerosis: Recent Evidence from Preclinical to Clinical Studies

Multiple sclerosis (MS) is a chronic inflammatory disease that attacks myelin, the protective sheath that covers nerves and causes progressive and serious communication issues between the brain, central nervous system, and the rest of the body[1]. Currently, it's estimated that over 2.3 million people worldwide, and over one million people in the US have a…

Regenerative Medicine or Surgery?

When you live with chronic pain, almost any treatment option that offers relief can be tempting. Undergoing surgery for joint pain is a serious decision. Surgery comes with many risks, including potentially long and painful recovery times, and there is no guarantee that surgical treatments will resolve your pain. Before deciding whether surgery is the…

Can Regenerative Medicine Help Manage Neurodegenerative Conditions?

Neurodegenerative conditions such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) occur when neuron populations begin to diminish. There is currently no cure for these types of diseases, though clinical trials to explore various treatment options are ongoing. In particular, regenerative medicine, also known as regenerative medicine, is being heavily researched…

Safety and Clinical Outcomes In Chronic Ischemic Stroke Patients After Implantation of Mesenchymal Stem Cells

According to the CDC, stroke continues to be a major cause of serious disability for adults. It is also estimated that nearly 800,000 people in the United States have a stroke each year[1]. While 80% of those experiencing a stroke survive for at least one year following the event, more than 70% will continue to…

Evaluating Stem Cells As A Treatment Option For Kidney Disease

Current estimates indicate that kidney disease currently affects over 37 million US adults and over 10% of the global population[1]. Characterized by gradual loss of function, kidney disease generally progresses over time and culminates in the inability to remove waste and excess fluid from the blood[2].   Often demonstrating little to no symptoms in its early…

The Efficacy Of Wharton’s Jelly Mesenchymal Stem Cells For Treating Type 2 Diabetes

According to recent data from the CDC, an estimated 30 million Americans currently have type 2 diabetes mellitus (T2DM), and another 88 million are considered to be prediabetic[1].  Occurring most often as a result of being overweight and/or sedimentary and often resulting in severe kidney, heart, or vision issues, T2DM has demonstrated to be difficult…

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