Mesenchymal Stem Cells

What Are Mesenchymal Stem Cells?

Mesenchymal stem cells are a specific type of stem cell. MSCs have been the subject of many medical studies and extensive research. MSCs are essentially the raw materials that the body uses to generate new tissues.  These versatile cells can differentiate or transform into many different forms of cells, including the following: Like many other…

How Do Mesenchymal Stem Cells Repair?

Over the last decade, the field of regenerative medicine has grown in research and awareness. This growth is thanks to mesenchymal stem cells (MSCs,) the type of cells most commonly explored for their powerful reparative properties. Medical professionals can harvest and concentrate these MSCs from multiple sources, making them more accessible. As a result, stem cells…

A Review of Current Mesenchymal Stem Cell Clinical Applications

Human mesenchymal stem cells (hMSCs) are multipotent adult stem cells found in tissue throughout the body, including in the umbilical cord, bone marrow, and adipose tissue. Capable of self-renewing and differentiating into multiple tissues including bone, cartilage, muscle, fat cells, and connective tissue[1], MSCs appear to have a wide range of potential for use as…

A Review of Current Perspectives of Regenerative Medicine in Orthopedic Surgery

It is estimated that over 126 million Americans, or nearly one in two adults, are affected with some form of regenerative medicine for musculoskeletal injuries disorder, condition, or injury - a number comparable to the percentage of the population currently living with a chronic lung or heart condition[1]. While there are a number of treatment…

Advancing Stem Cell Treatment for Traumatic Brain Injury

According to the CDC, in 2019, traumatic brain injury (TBI) contributed to nearly 61,000 deaths in the United States alone[1]. While there are several clinical treatments designed to address the neurological dysfunction after sustaining a TBI, including hyperbaric oxygen, brain stimulation, and behavioral therapy, none appear to produce satisfactory or lasting results. In recent years,…

Using Mesenchymal Stem Cells for Musculoskeletal Regeneration in Clinical Applications: Current Status and Perspectives

Research exploring the benefits of mesenchymal stem cells (MSCs) has demonstrated tremendous potential as a regenerative therapy option for the musculoskeletal system. Research into these cell-based regenerative therapies is promising, and they must continue to provide the data necessary to show their therapeutic potential in clinical settings.  In this review, Steinert et al. review and…

Treating Spinal Cord Injuries with Intravenous Infusion of Auto Serum-Expanded Autologous Mesenchymal Stem Cells

stem cell therapy for spinal cord injury (SCI) continues to be a significant cause of disability. In fact, it is estimated that annual SCIs account for nearly 18,000 injuries in the United States and between 250,000 and 500,000 injuries worldwide[1]. Additionally, an estimated 294,000 people in the United States are currently living with some form…

Treating Autoimmune Disease Through Adult Regenerative Medicine

stem cell therapy for autoimmune conditionss occur as a result of the body’s natural immune system mistakenly attacking and damaging healthy, normal cells and tissue. Currently, an estimated 60 different autoimmune diseases affect between 5 and 8 percent of the U.S. population[1]; making it one of the largest disease burdens faced today. Divided into two…

Mesenchymal Stem Cell-Based Therapy: Potential Benefits For Osteoarthritis

Affecting over 52 million people, or nearly 25% of the adult patients, osteoarthritis (OA) continues to be the leading cause of disability for people in the United States. Occurring as a result of the protective cartilage, or articular cartilage, that cushions the ends of the bones breaking down, OA can occur in any joint, but…

Examining the Safety and Efficacy of Regenerative Medicine Treating Neural Damage in Patients with Multiple Sclerosis

Multiple sclerosis (MS) is a progressive and disabling stem cell therapy for autoimmune conditions that affects the brain and central nervous system.  As MS progresses, the body’s immune system attacks the protective sheath (myelin) that covers nerve fibers resulting in axonal damage and loss that eventually results in paralysis of the limbs; the condition also…

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