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Neurodegenerative Diseases

Can Regenerative Medicine Help Manage Neurodegenerative Conditions?

Neurodegenerative conditions such as Alzheimer’s disease (AD), stem cell therapy for Parkinson disease’s disease (PD), and amyotrophic lateral sclerosis (ALS) occur when neuron populations begin to diminish. There is currently no cure for these types of diseases, though clinical trials to explore various treatment options are ongoing. In particular, regenerative medicine, also known as regenerative…

The Role of Mesenchymal Stem Cells in Counteracting Oxidative Stress-Related Neurodegeneration

Neurodegenerative diseases affect over 50 million Americans each year and occur as a result of nerve cells in the brain, peripheral nervous system, and the central nervous system slowly and progressively losing function before eventually dying[1]. Although there are over 600 known neurological disorders, the most common neurodegenerative diseases continue to be Alzheimer’s disease (AD),…

Can Stem Cells Regrow Brain Tissue?

In neurodegenerative conditions and cases of brain damage such as traumatic brain injury (TBI), the goal of treatment is usually to manage symptoms and prevent or slow the rate of further damage. Yet, ongoing research suggests stem cells could play an important role in creating new neurons, potentially resulting in repair of central nervous system…

Using Mesenchymal Stem Cells As A Therapeutic Strategy for Neurodegenerative Diseases

Neurodegenerative disease is a broad term encompassing a number of chronic, progressive diseases that result in degeneration and or death of neurons; these diseases include stem cell therapy for Parkinson disease’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS) and affect over 50 million Americans each year[1][2]. Since neurons possess a very limited…

Exploring Thymosin β4 as a Restorative/Regenerative Treatment Option for Neurological Injury and Neurodegenerative Diseases

Oligodendrocytes are key neural cells responsible for producing myelin sheaths that wrap around neuronal axons in the central nervous system[1]. Considering that thymosin β4’s (Tβ4) ability to promote neurological recovery in a range of neurological diseases has been well established, Chopp & Zhang (2015) propose oligodendrogenesis as the common link by which Tβ4 supports and…

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