Multiple sclerosis (MS) is a neurological disorder that can affect all of your body systems. People suffering from MS often report neurological, muscular, and skin problems as the disease progresses. If you have MS, you may develop puzzling skin symptoms and conditions that need to be addressed. 

Your skin is the largest organ in your body, and it may need extra support if you have multiple sclerosis. Learn how MS symptoms and medications can affect your skin in your daily life. 

Why MS Causes Skin Problems

Multiple sclerosis is a neurodegenerative condition that leads to increasing nerve damage over time. As a result, the ways your body experiences pain and physical sensations will change. 

Nerve Degeneration

Some of this is purely neurological. As your nerves experience damage from this condition, they may misfire pain or sensitivity signals within your skin. You could have odd sensations, sensitivity to cold and light touch, and other skin problems. 

Medication Side Effects

Additionally, Multiple sclerosis medications can lead to negative effects on your skin. Some of these prescriptions may irritate or inflame soft tissues in your body. As a result, you may experience infections, lesions, and rashes. 

Common Neurological Skin Symptoms and Problems 

When your nerves aren’t working properly, the way your body senses and responds to external stimuli (like touch) changes. These symptoms are what’s known as neurological skin problems. They don’t directly affect the appearance or texture of your skin, but these issues do impair your daily life. 

Paresthesia

One of the earliest symptoms of Multiple sclerosis is paresthesia. This broad skin sensation can manifest in many different ways. Not everyone who experiences paresthesia has MS, but most MS patients deal with paresthesia at some point. 

Some symptoms of paresthesia include:

  • Numbness
  • Tingling
  • Prickling sensations
  • Burning
  • “Pins and needles” 
  • Tickling sensations
  • Feeling like your skin is “crawling”

These symptoms show up even when nothing is physically touching your skin. Paresthesia is most common in your extremities — fingers, toes, hands, feet, legs, and arms. However, you may experience paresthesia in different spots on your body over time. 

Neuropathic Itch

This skin problem is slightly different from paresthesia. When you develop neuropathic itch, it may feel like nothing will relieve the deep burning itch. Many MS patients struggle with this, and it doesn’t always involve external touches or stimuli. 

Another name for neuropathic itch is pruritus. Even if there’s nothing physical causing the itch, it’s still a real sensation. It can be frustrating when the itch won’t resolve, even if you’ve scratched your skin excessively. 

Skin Sensitivity: Cold, Touch, and More

MS patients experience extreme sensitivity to heat, cold, and touch due to nerve damage. This means even the lightest touch or slightest change in temperature can trigger a strong reaction in your body. 

This makes everyday life difficult for obvious reasons. When you feel extreme pain and aversion to light touch or mild temperatures, it can be difficult to complete tasks and participate in society. 

MS Medication and Skin Problems

Many MS patients have medications prescribed from their physician. However, the side effects aren’t always pleasant, particularly when it comes to your skin. 

There are a wide variety of prescription drugs used to treat MS, so your specific symptoms will depend on what you’re taking. For example, monoclonal antibodies target certain immune cells to reduce the neurodegenerative and inflammatory effects of MS. However, this can irritate your skin and cause other unwanted side effects.  

Here are some of the skin symptoms you may notice after taking MS medications. 

Hives and Rashes

Patchy, itchy spots and raised hives can both stem from MS medications. This is because MS prescriptions deal with your immune system, inflammatory responses, and other bodily processes. These systems can and do interact with your skin, and sometimes, it responds by breaking out in hives or rashes. 

Redness and Flushing

Some oral MS medications cause hot flashes, which make your skin look red and flushed. This is similar to the temporary skin sensations caused by exercise or anxiety. Most flushing sensations go away within 30 minutes of taking your medication, but they can still be a nuisance. 

Skin Lesions

Some injections and infusions that treat MS can lead to skin lesions, which can affect your confidence and comfort. You may notice large or small skin lesions, with some being discolored or bruised. 

Secondary Infections

When you have MS, your immune system constantly works overtime. This can weaken your defenses against secondary infections, like skin infections. 

Scratching weakens your skin barrier, which can allow bacteria to enter your skin matrix and cause infections. If you’re dealing with neuropathic itch, you’re especially at risk. 

Certain MS medications also make you more susceptible to skin infections. Injectable prescriptions carry the risk of exposing bacteria to different layers of your skin. Improper needle use and poor needle hygiene can both result in skin infections. 

You’ll need antibiotic treatments for secondary skin infections, as these are bacterial and won’t go away on their own. Always consult your doctor for help with skin infections. 

Care for Your Body to Reduce Your Skin’s Risk

Having MS is exhausting and can be debilitating. However, practicing physical and emotional self-care whenever possible can be beneficial. Caring for your overall health can reduce the impact MS has on your skin, making it less susceptible to infections and unpleasant symptoms. 

Some forms of self-care for MS patients include:

  • Getting plenty of rest
  • Exercising regularly
  • Journaling
  • Meditating
  • Eating a nutritious diet
  • Doing yoga 
  • Spending time in MS support groups
  • Talk therapy

These are all wonderful strategies for supporting your psychological and physical health when you have MS. 

Be Prepared: Know the Most Common MS-Related Skin Symptoms

You can prepare yourself by learning about what you can expect after an MS diagnosis. MS has many detrimental effects on the body, but you can reduce some of these effects through stress relief and self-care. As you improve your overall well-being, you may notice skin improvements as well. 

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